WormBase Tree Display for Gene: WBGene00002037
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| WBGene00002037 | SMap | S_parent | Sequence | F46C3 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 3 | |||||||
| Name | CGC_name | hum-4 | |||||||
| Sequence_name | F46C3.3 | ||||||||
| Molecular_name (27) | |||||||||
| Other_name | CELE_F46C3.3 | Accession_evidence | NDB | BX284606 | |||||
| Public_name | hum-4 | ||||||||
| DB_info | Database (12) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:26 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| 2 | 10 Jan 2006 15:12:44 | WBPerson1983 | Event | Split_into | WBGene00044702 | ||||
| 3 | 10 Jan 2006 15:13:24 | WBPerson1983 | Event | Split_into | WBGene00044703 | ||||
| Split_into | WBGene00044702 | ||||||||
| WBGene00044703 | |||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | hum | ||||||||
| Allele (187) | |||||||||
| Legacy_information | NMK. Encodes predicted unconventional myosin, novel, probably class XII.[DU] X 3.33 | ||||||||
| Strain | WBStrain00031484 | ||||||||
| WBStrain00049466 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (20) | |||||||||
| Ortholog (34) | |||||||||
| Paralog (21) | |||||||||
| Structured_description | Concise_description | hum-4 encodes a class XII myosin, an unconventional myosin; HUM-4 binds bovine calmodulin in vitro in a calcium-dependent manner. | Paper_evidence | WBPaper00002905 | |||||
| WBPaper00031011 | |||||||||
| Curator_confirmed | WBPerson48 | ||||||||
| WBPerson1843 | |||||||||
| Date_last_updated | 04 May 2010 00:00:00 | ||||||||
| Automated_description | Enables calmodulin binding activity. Predicted to be involved in actin filament organization and vesicle transport along actin filament. Predicted to be located in several cellular components, including actin cytoskeleton; actin-based cell projection; and vesicle. Predicted to be part of myosin complex. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 3 and sensorineural hearing loss. Is an ortholog of human MYO15A (myosin XVA) and MYO16 (myosin XVI). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0110488 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:7594) | ||||
| DOID:10003 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:7594) | ||||||
| Molecular_info | Corresponding_CDS | F46C3.3a | |||||||
| F46C3.3b | |||||||||
| F46C3.3c | |||||||||
| F46C3.3d | |||||||||
| F46C3.3e | |||||||||
| F46C3.3f | |||||||||
| F46C3.3g | |||||||||
| F46C3.3h | |||||||||
| Corresponding_CDS_history | F46C3.3:wp83 | ||||||||
| F46C3.3:wp153 | |||||||||
| F46C3.3a:wp214 | |||||||||
| F46C3.3a:wp271 | |||||||||
| F46C3.3b:wp214 | |||||||||
| F46C3.3c:wp214 | |||||||||
| F46C3.3d:wp214 | |||||||||
| F46C3.3e:wp214 | |||||||||
| F46C3.3f:wp271 | |||||||||
| Corresponding_transcript (11) | |||||||||
| Other_sequence (14) | |||||||||
| Associated_feature | WBsf671031 | ||||||||
| WBsf671032 | |||||||||
| WBsf671033 | |||||||||
| WBsf671034 | |||||||||
| WBsf671035 | |||||||||
| WBsf1006994 | |||||||||
| WBsf1023866 | |||||||||
| WBsf1023867 | |||||||||
| WBsf237965 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00114836 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00047504 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00000806 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00015073 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr1026094 | ||||||||
| Expr1031192 | |||||||||
| Expr1151341 | |||||||||
| Expr2012646 | |||||||||
| Expr2030882 | |||||||||
| Drives_construct | WBCnstr00036503 | ||||||||
| Construct_product | WBCnstr00036503 | ||||||||
| Microarray_results (28) | |||||||||
| Expression_cluster (168) | |||||||||
| Interaction (19) | |||||||||
| Map_info | Map | X | Position | 3.7349 | Error | 0.029849 | |||
| Positive | Positive_clone | F46C3 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 4427 | |||||||
| 4569 | |||||||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00002905 | ||||||||
| WBPaper00015440 | |||||||||
| WBPaper00022442 | |||||||||
| WBPaper00024261 | |||||||||
| WBPaper00025258 | |||||||||
| WBPaper00031011 | |||||||||
| WBPaper00038491 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00064860 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
