WormBase Tree Display for Gene: WBGene00002037
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WBGene00002037 | SMap | S_parent | Sequence | F46C3 | |||
---|---|---|---|---|---|---|---|
Identity | Version | 3 | |||||
Name | CGC_name | hum-4 | |||||
Sequence_name | F46C3.3 | ||||||
Molecular_name (27) | |||||||
Other_name | CELE_F46C3.3 | Accession_evidence | NDB | BX284606 | |||
Public_name | hum-4 | ||||||
DB_info | Database (12) | ||||||
Species | Caenorhabditis elegans | ||||||
History | Version_change (3) | ||||||
Split_into | WBGene00044702 | ||||||
WBGene00044703 | |||||||
Status | Live | ||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | hum | ||||||
Allele (187) | |||||||
Legacy_information | NMK. Encodes predicted unconventional myosin, novel, probably class XII.[DU] X 3.33 | ||||||
Strain | WBStrain00031484 | ||||||
WBStrain00049466 | |||||||
RNASeq_FPKM (74) | |||||||
GO_annotation (20) | |||||||
Ortholog (34) | |||||||
Paralog (21) | |||||||
Structured_description | Concise_description | hum-4 encodes a class XII myosin, an unconventional myosin; HUM-4 binds bovine calmodulin in vitro in a calcium-dependent manner. | Paper_evidence | WBPaper00002905 | |||
WBPaper00031011 | |||||||
Curator_confirmed | WBPerson48 | ||||||
WBPerson1843 | |||||||
Date_last_updated | 04 May 2010 00:00:00 | ||||||
Automated_description | Enables calmodulin binding activity. Predicted to be involved in actin filament organization and vesicle transport along actin filament. Predicted to be located in several cellular components, including actin cytoskeleton; actin-based cell projection; and vesicle. Predicted to be part of myosin complex. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 3 and sensorineural hearing loss. Is an ortholog of human MYO15A (myosin XVA) and MYO16 (myosin XVI). | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Disease_info | Potential_model | DOID:0110488 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:7594) | ||
DOID:10003 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:7594) | ||||
Molecular_info | Corresponding_CDS | F46C3.3a | |||||
F46C3.3b | |||||||
F46C3.3c | |||||||
F46C3.3d | |||||||
F46C3.3e | |||||||
F46C3.3f | |||||||
F46C3.3g | |||||||
F46C3.3h | |||||||
Corresponding_CDS_history | F46C3.3:wp83 | ||||||
F46C3.3:wp153 | |||||||
F46C3.3a:wp214 | |||||||
F46C3.3a:wp271 | |||||||
F46C3.3b:wp214 | |||||||
F46C3.3c:wp214 | |||||||
F46C3.3d:wp214 | |||||||
F46C3.3e:wp214 | |||||||
F46C3.3f:wp271 | |||||||
Corresponding_transcript (11) | |||||||
Other_sequence (14) | |||||||
Associated_feature | WBsf671031 | ||||||
WBsf671032 | |||||||
WBsf671033 | |||||||
WBsf671034 | |||||||
WBsf671035 | |||||||
WBsf1006994 | |||||||
WBsf1023866 | |||||||
WBsf1023867 | |||||||
WBsf237965 | |||||||
Experimental_info | RNAi_result | WBRNAi00114836 | Inferred_automatically | RNAi_primary | |||
WBRNAi00047504 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00000806 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00015073 | Inferred_automatically | RNAi_primary | |||||
Expr_pattern | Expr1026094 | ||||||
Expr1031192 | |||||||
Expr1151341 | |||||||
Expr2012646 | |||||||
Expr2030882 | |||||||
Drives_construct | WBCnstr00036503 | ||||||
Construct_product | WBCnstr00036503 | ||||||
Microarray_results (28) | |||||||
Expression_cluster (168) | |||||||
Interaction (19) | |||||||
Map_info | Map | X | Position | 3.7349 | Error | 0.029849 | |
Positive | Positive_clone | F46C3 | Inferred_automatically | From sequence, transcript, pseudogene data | |||
Mapping_data | Multi_point | 4427 | |||||
4569 | |||||||
Pseudo_map_position | |||||||
Reference | WBPaper00002905 | ||||||
WBPaper00015440 | |||||||
WBPaper00022442 | |||||||
WBPaper00024261 | |||||||
WBPaper00025258 | |||||||
WBPaper00031011 | |||||||
WBPaper00038491 | |||||||
WBPaper00055090 | |||||||
WBPaper00064860 | |||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||
Method | Gene |