WormBase Tree Display for Gene: WBGene00002090
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| WBGene00002090 | Evidence | Paper_evidence | WBPaper00003057 | ||||||
|---|---|---|---|---|---|---|---|---|---|
| WBPaper00004623 | |||||||||
| SMap | S_parent | Sequence | ZK1251 | ||||||
| Identity | Version | 1 | |||||||
| Name | CGC_name | ins-7 | Person_evidence | WBPerson339 | |||||
| Sequence_name | ZK1251.2 | ||||||||
| Molecular_name | ZK1251.2a | ||||||||
| ZK1251.2a.1 | |||||||||
| CE03849 | |||||||||
| ZK1251.2b | |||||||||
| CE47202 | |||||||||
| ZK1251.2b.1 | |||||||||
| Other_name | CELE_ZK1251.2 | Accession_evidence | NDB | BX284604 | |||||
| Public_name | ins-7 | ||||||||
| DB_info | Database | AceView | gene | 4K446 | |||||
| WormQTL | gene | WBGene00002090 | |||||||
| WormFlux | gene | WBGene00002090 | |||||||
| NDB | locus_tag | CELE_ZK1251.2 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00002090|UniProtKB=Q23430 | |||||||
| family | PTHR33893 | ||||||||
| NCBI | gene | 191688 | |||||||
| RefSeq | protein | NM_001268489.3 | |||||||
| NM_001268488.3 | |||||||||
| SwissProt | UniProtAcc | Q23430 | |||||||
| TrEMBL | UniProtAcc | H9G2S9 | |||||||
| UniProt_GCRP | UniProtAcc | Q23430 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:26 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | ins | ||||||||
| Allele (14) | |||||||||
| Legacy_information | [Ferguson K] ins for INSulin related. No mutants known. | ||||||||
| Strain | WBStrain00032086 | ||||||||
| WBStrain00048368 | |||||||||
| WBStrain00048365 | |||||||||
| WBStrain00048374 | |||||||||
| WBStrain00048360 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00023681 | ||||||||
| 00023682 | |||||||||
| 00023683 | |||||||||
| 00023684 | |||||||||
| 00078437 | |||||||||
| 00110010 | |||||||||
| 00110011 | |||||||||
| Ortholog | WBGene00053993 | Caenorhabditis remanei | From_analysis | OMA | |||||
| WBGene00083908 | Caenorhabditis remanei | From_analysis | OMA | ||||||
| WBGene00140898 | Caenorhabditis brenneri | From_analysis | WormBase-Compara | ||||||
| WBGene00158728 | Caenorhabditis brenneri | From_analysis | WormBase-Compara | ||||||
| CSP40.g8612 | Caenorhabditis tribulationis | From_analysis | WormBase-Compara | ||||||
| Csp11.Scaffold629.g16423 | Caenorhabditis tropicalis | From_analysis | WormBase-Compara | ||||||
| Csp5_scaffold_00132.g5201 | Caenorhabditis sinica | From_analysis | WormBase-Compara | ||||||
| chrIV_pilon.g11377 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| Paralog (19) | |||||||||
| Structured_description | Concise_description | ins-7 encodes an insulin/IGF-1-like peptide; INS-7 is one of 40 insulin-like peptides in C. elegans; INS-7 likely functions as an agonist for the DAF-2 insulin/IGF-1 receptor, as loss of ins-7 activity via RNAi results in: 1) a significantly increased lifespan that is not further extended in long-lived daf-2 mutant animals, and 2) an increased frequency of dauer formation in animals containing an incompletely penetrant daf-2 mutation; an ins-7 promoter fusion is expressed in amphid sensory neurons, labial neurons, the nerve ring, and ventral cord and tail neurons; ins-7 expression is positively regulated by DAF-2-mediated insulin signaling, suggesting that a positive feedback loop involving INS-7 may amplify DAF-2 pathway activity. | Paper_evidence | WBPaper00004623 | |||||
| WBPaper00005976 | |||||||||
| WBPaper00029214 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 13 Dec 2010 00:00:00 | ||||||||
| Automated_description | Predicted to enable hormone activity. Involved in olfactory learning. Predicted to be located in extracellular region and membrane. Expressed in several structures, including distal tip cell; egg-laying apparatus; head muscle; neurons; and somatic nervous system. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | ZK1251.2a | |||||||
| ZK1251.2b | |||||||||
| Corresponding_transcript | ZK1251.2a.1 | ||||||||
| ZK1251.2b.1 | |||||||||
| Associated_feature | WBsf230601 | ||||||||
| Experimental_info | RNAi_result (23) | ||||||||
| Expr_pattern | Expr869 | ||||||||
| Expr7824 | |||||||||
| Expr10634 | |||||||||
| Expr10845 | |||||||||
| Expr11930 | |||||||||
| Expr1014616 | |||||||||
| Expr1162617 | |||||||||
| Expr2012778 | |||||||||
| Expr2031017 | |||||||||
| Drives_construct | WBCnstr00012946 | ||||||||
| WBCnstr00013458 | |||||||||
| WBCnstr00017002 | |||||||||
| WBCnstr00017780 | |||||||||
| WBCnstr00019811 | |||||||||
| WBCnstr00020764 | |||||||||
| WBCnstr00036462 | |||||||||
| Construct_product | WBCnstr00016055 | ||||||||
| WBCnstr00020764 | |||||||||
| WBCnstr00036462 | |||||||||
| Microarray_results (18) | |||||||||
| Expression_cluster (234) | |||||||||
| Interaction (153) | |||||||||
| WBProcess | WBbiopr:00000001 | ||||||||
| WBbiopr:00000008 | |||||||||
| WBbiopr:00000039 | |||||||||
| Map_info | Map | IV | Position | 4.35256 | Error | 0.001133 | |||
| Positive | Positive_clone | ZK1251 | Author_evidence | Ferguson KC | |||||
| Inferred_automatically | From sequence, transcript, pseudogene data | ||||||||
| Mapping_data | Multi_point | 5260 | |||||||
| 5454 | |||||||||
| Pseudo_map_position | |||||||||
| Reference (61) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
