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WormBase Tree Display for Gene_class: ins

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Name Class

insDescriptionINSulin related
Designating_laboratoryCE
Genes (105)
Old_memberCbn-ins-2
Cre-ins-27
Cbr-ins-32
Cre-ins-1
Cbn-ins-1
Cbr-ins-6
Cbr-ins-6.2
Cre-ins-27.2
Cbr-ins-21
Cbr-ins-21.1
Other_nameilp
RemarkAbout 12 separate insulin genes had been described in three separate papers before a consistant nomenclature first appeared in Pierce et al. 2001. This paper also expanded the family to 37 members. Occasional use of other names has also added some confusion to this gene family. [krb 031031]Paper_evidenceWBPaper00003057
WBPaper00003189
WBPaper00004209
WBPaper00004263
igf-1 became an other_name of ins-18 [030226 ck1]
ilp-1 became an other_name of ins-1 [030226 ck1]
ins-1 became an other name of ins-18 [031031 krb]
Ceinsulin-1 became an other_name of ins-18 [030226 ck1]
ins-2 and Ceinsulin-2 became other names of ins-17 [031031 krb]
There is an ins-2 locus which is an EMBL gene name (not CGC-approved) and became an other-name of ins-17 as their protein sequences are identical. This unofficial ins-2 is not the same as the CGG ins-2 (ZK75.2)Curator_confirmedWBPerson1845
There is an ins-1 locus which is an EMBL gene name (not CGC-approved) and became an other-name of ins-18 as their protein sequences are identical. This unofficial ins-1 is not the same as the CGG ins-1 (F13B12.5)Curator_confirmedWBPerson1845
About 12 separate insulin genes had been described in three separate papers before a consistant nomenclature first appeared in Pierce et al. 2001 (WBPaper00004623). This paper also expanded the family to 37 members. Occasional use of other names has also added some confusion to this gene family. [krb 031031]Paper_evidenceWBPaper00004623