WormBase Tree Display for Gene: WBGene00001996
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| WBGene00001996 | SMap | S_parent | Sequence | K01G5 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | hpl-2 | |||||||
| Sequence_name | K01G5.2 | ||||||||
| Molecular_name | K01G5.2a | ||||||||
| K01G5.2a.1 | |||||||||
| CE16191 | |||||||||
| K01G5.2b | |||||||||
| CE25037 | |||||||||
| K01G5.2c | |||||||||
| CE25038 | |||||||||
| K01G5.2b.1 | |||||||||
| K01G5.2c.1 | |||||||||
| Other_name | CELE_K01G5.2 | Accession_evidence | NDB | BX284603 | |||||
| Public_name | hpl-2 | ||||||||
| DB_info | Database | AceView | gene | 3L842 | |||||
| WormQTL | gene | WBGene00001996 | |||||||
| WormFlux | gene | WBGene00001996 | |||||||
| NDB | locus_tag | CELE_K01G5.2 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00001996|UniProtKB=Q9U3C6 | |||||||
| family | PTHR10503 | ||||||||
| NCBI | gene | 176506 | |||||||
| RefSeq | protein | NM_001027481.5 | |||||||
| NM_001027482.4 | |||||||||
| NM_001027483.3 | |||||||||
| SwissProt | UniProtAcc | G5EDE2 | |||||||
| UniProt_GCRP | UniProtAcc | G5EDE2 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:26 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | hpl | ||||||||
| Allele (56) | |||||||||
| Strain (12) | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (72) | |||||||||
| Contained_in_operon | CEOP3701 | ||||||||
| Ortholog (11) | |||||||||
| Paralog | WBGene00044225 | Caenorhabditis elegans | From_analysis | modENCODE_Pseudogenes | |||||
| WBGene00195045 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00194861 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00017990 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WBGene00021913 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00017993 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00010363 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | hpl-2 encodes one of two C. elegans heterochromatin protein 1 (HP1) homologs; hpl-2 activity is required for silencing of transgenes in the germline, germline development, and vulval cell fate specification; in addition, hpl-2 negatively regulates RNA-mediated interference (RNAi); hpl-2 also functions redundantly with hpl-1 in larval, somatic gonad and germline development, and redundantly with hpl-1, lin-13, lin-15A, lin-9, and lin-35 in vulval development; HPL-2 reporter fusion proteins are expressed in nuclei throughout the life cycle with expression also seen in the germline and developing oocytes; in nuclei, HPL-2 fusion proteins are associated with condensed chromatin; HPL-2::RFP foci do not significantly overlap with those of HPL-1. | Paper_evidence | WBPaper00005176 | |||||
| WBPaper00026665 | |||||||||
| WBPaper00028349 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 09 May 2007 00:00:00 | ||||||||
| Automated_description | Enables H3K27me3 modified histone binding activity and chromatin binding activity. Involved in several processes, including developmental process involved in reproduction; nematode larval development; and regulation of gene expression. Located in nuclear periphery. Expressed in several structures, including AWCL; AWCR; hyp7 syncytium; and vulval precursor cell. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | K01G5.2a | |||||||
| K01G5.2b | |||||||||
| K01G5.2c | |||||||||
| Corresponding_transcript | K01G5.2a.1 | ||||||||
| K01G5.2b.1 | |||||||||
| K01G5.2c.1 | |||||||||
| Other_sequence | AF123573 | ||||||||
| AF123574 | |||||||||
| MH07860 | |||||||||
| Associated_feature | WBsf667411 | ||||||||
| WBsf227507 | |||||||||
| WBsf227508 | |||||||||
| WBsf227509 | |||||||||
| WBsf227510 | |||||||||
| Gene_product_binds (374) | |||||||||
| Transcription_factor | WBTranscriptionFactor001155 | ||||||||
| Experimental_info (12) | |||||||||
| Map_info | Map | III | Position | 5.23643 | Error | 0.026273 | |||
| Positive | Positive_clone | K01G5 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Pseudo_map_position | |||||||||
| Reference (88) | |||||||||
| Remark | Sequence connection from [Couteau F, Muller F, Palladino, F], 02/06/13 krb. | ||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
