WormBase Tree Display for Gene: WBGene00001996
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WBGene00001996 | SMap | S_parent | Sequence | K01G5 | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 1 | |||||||
Name | CGC_name | hpl-2 | |||||||
Sequence_name | K01G5.2 | ||||||||
Molecular_name | K01G5.2a | ||||||||
K01G5.2a.1 | |||||||||
CE16191 | |||||||||
K01G5.2b | |||||||||
CE25037 | |||||||||
K01G5.2c | |||||||||
CE25038 | |||||||||
K01G5.2b.1 | |||||||||
K01G5.2c.1 | |||||||||
Other_name | CELE_K01G5.2 | Accession_evidence | NDB | BX284603 | |||||
Public_name | hpl-2 | ||||||||
DB_info | Database | AceView | gene | 3L842 | |||||
WormQTL | gene | WBGene00001996 | |||||||
WormFlux | gene | WBGene00001996 | |||||||
NDB | locus_tag | CELE_K01G5.2 | |||||||
Panther | gene | CAEEL|WormBase=WBGene00001996|UniProtKB=Q9U3C6 | |||||||
family | PTHR10503 | ||||||||
NCBI | gene | 176506 | |||||||
RefSeq | protein | NM_001027481.5 | |||||||
NM_001027482.4 | |||||||||
NM_001027483.3 | |||||||||
SwissProt | UniProtAcc | G5EDE2 | |||||||
UniProt_GCRP | UniProtAcc | G5EDE2 | |||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 07 Apr 2004 11:29:26 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | hpl | ||||||||
Allele (56) | |||||||||
Strain (12) | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation (72) | |||||||||
Contained_in_operon | CEOP3701 | ||||||||
Ortholog (11) | |||||||||
Paralog | WBGene00044225 | Caenorhabditis elegans | From_analysis | modENCODE_Pseudogenes | |||||
WBGene00195045 | Caenorhabditis elegans | From_analysis | Panther | ||||||
WormBase-Compara | |||||||||
WBGene00194861 | Caenorhabditis elegans | From_analysis | Panther | ||||||
WormBase-Compara | |||||||||
WBGene00017990 | Caenorhabditis elegans | From_analysis | Panther | ||||||
WBGene00021913 | Caenorhabditis elegans | From_analysis | Panther | ||||||
WormBase-Compara | |||||||||
WBGene00017993 | Caenorhabditis elegans | From_analysis | Panther | ||||||
WormBase-Compara | |||||||||
WBGene00010363 | Caenorhabditis elegans | From_analysis | Panther | ||||||
WormBase-Compara | |||||||||
Structured_description | Concise_description | hpl-2 encodes one of two C. elegans heterochromatin protein 1 (HP1) homologs; hpl-2 activity is required for silencing of transgenes in the germline, germline development, and vulval cell fate specification; in addition, hpl-2 negatively regulates RNA-mediated interference (RNAi); hpl-2 also functions redundantly with hpl-1 in larval, somatic gonad and germline development, and redundantly with hpl-1, lin-13, lin-15A, lin-9, and lin-35 in vulval development; HPL-2 reporter fusion proteins are expressed in nuclei throughout the life cycle with expression also seen in the germline and developing oocytes; in nuclei, HPL-2 fusion proteins are associated with condensed chromatin; HPL-2::RFP foci do not significantly overlap with those of HPL-1. | Paper_evidence | WBPaper00005176 | |||||
WBPaper00026665 | |||||||||
WBPaper00028349 | |||||||||
Curator_confirmed | WBPerson1843 | ||||||||
WBPerson567 | |||||||||
Date_last_updated | 09 May 2007 00:00:00 | ||||||||
Automated_description | Enables H3K27me3 modified histone binding activity and chromatin binding activity. Involved in several processes, including developmental process involved in reproduction; nematode larval development; and regulation of gene expression. Located in nuclear periphery. Expressed in several structures, including AWCL; AWCR; hyp7 syncytium; and vulval precursor cell. | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Molecular_info | Corresponding_CDS (3) | ||||||||
Corresponding_transcript | K01G5.2a.1 | ||||||||
K01G5.2b.1 | |||||||||
K01G5.2c.1 | |||||||||
Other_sequence | AF123573 | ||||||||
AF123574 | |||||||||
MH07860 | |||||||||
Associated_feature | WBsf667411 | ||||||||
WBsf227507 | |||||||||
WBsf227508 | |||||||||
WBsf227509 | |||||||||
WBsf227510 | |||||||||
Gene_product_binds (374) | |||||||||
Transcription_factor | WBTranscriptionFactor001155 | ||||||||
Experimental_info (12) | |||||||||
Map_info | Map | III | Position | 5.23643 | Error | 0.026273 | |||
Positive | Positive_clone | K01G5 | Inferred_automatically | From CDS info | |||||
From sequence, transcript, pseudogene data | |||||||||
Pseudo_map_position | |||||||||
Reference (88) | |||||||||
Remark | Sequence connection from [Couteau F, Muller F, Palladino, F], 02/06/13 krb. | ||||||||
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
Method | Gene |