WormBase Tree Display for Gene: WBGene00001688
expand all nodes | collapse all nodes | view schema
| WBGene00001688 | Evidence | CGC_data_submission | |||||||
|---|---|---|---|---|---|---|---|---|---|
| SMap | S_parent | Sequence | F22B7 | ||||||
| Identity | Version | 1 | |||||||
| Name | CGC_name | gpr-1 | Person_evidence | WBPerson732 | |||||
| Sequence_name | F22B7.13 | ||||||||
| Molecular_name | F22B7.13 | ||||||||
| F22B7.13.1 | |||||||||
| CE24910 | |||||||||
| Other_name | ags-3.2 | ||||||||
| lap-2/ags-3.2 | Paper_evidence | WBPaper00010166 | |||||||
| CELE_F22B7.13 | Accession_evidence | NDB | BX284603 | ||||||
| Public_name | gpr-1 | ||||||||
| DB_info | Database | AceView | gene | 3J719 | |||||
| WormQTL | gene | WBGene00001688 | |||||||
| WormFlux | gene | WBGene00001688 | |||||||
| NDB | locus_tag | CELE_F22B7.13 | |||||||
| NCBI | gene | 176210 | |||||||
| RefSeq | protein | NM_066499.5 | |||||||
| SwissProt | UniProtAcc | Q95QJ7 | |||||||
| TREEFAM | TREEFAM_ID | TF318159 | |||||||
| UniProt_GCRP | UniProtAcc | Q95QJ7 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:25 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | gpr | ||||||||
| Allele (26) | |||||||||
| Strain | WBStrain00036782 | ||||||||
| WBStrain00007343 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (15) | |||||||||
| Contained_in_operon | CEOP3875 | ||||||||
| Ortholog (20) | |||||||||
| Paralog | WBGene00001689 | Caenorhabditis elegans | From_analysis | TreeFam | |||||
| Inparanoid_8 | |||||||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | gpr-1 encodes an extremely similar (97% identity) paralog of GPR-2; GPR-1(and GPR-2) proteins have two N-terminal tetratricopeptide-like motifs anda C-terminal GoLoco/GPR (G protein regulatory) motif, the latter of whichhas also been found in mammalian AGS3 and Drosophila Pins; GPR-1 isrequired for normally asymmetrical cleavage of one-cell embryos; GPR-1 andGPR-2 form a high molecular weight (~700 kDa) complex that includes LIN-5;GPR-1 binds GDP-bound GOA-1 via a GoLoco/GPR motif, and depends on RIC-8for this binding; GPR-1/2, GOA-1, and LIN-5 colocalize at the cortex ofearly embryos; cortical enrichment of GPR-1 requires LIN-5, PAR-2, PAR-3,and LET-99; the asymmetric distribution of GPR-1/2 and LET-99 in EMS cellsis dependent on MES-1/SRC-1 signaling; GPR-1/2 is co-immunoprecipitatedwith RIC-8 and GPA-16. | Paper_evidence | WBPaper00005878 | |||||
| WBPaper00005918 | |||||||||
| WBPaper00005945 | |||||||||
| WBPaper00006289 | |||||||||
| WBPaper00024244 | |||||||||
| WBPaper00024481 | |||||||||
| WBPaper00026807 | |||||||||
| Curator_confirmed | WBPerson567 | ||||||||
| Date_last_updated | 06 Sep 2006 00:00:00 | ||||||||
| Automated_description | Enables G-protein alpha-subunit binding activity and GDP-dissociation inhibitor activity. Predicted to be involved in cell division. Located in aster and cell cortex. Expressed in P lineage cell. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | F22B7.13 | |||||||
| Corresponding_transcript | F22B7.13.1 | ||||||||
| Other_sequence | CJC06602_1 | ||||||||
| CBC04217_1 | |||||||||
| Associated_feature | WBsf225448 | ||||||||
| Experimental_info | RNAi_result (55) | ||||||||
| Expr_pattern | Expr2564 | ||||||||
| Expr10765 | |||||||||
| Expr1031007 | |||||||||
| Expr1149216 | |||||||||
| Expr2012213 | |||||||||
| Expr2030449 | |||||||||
| Drives_construct | WBCnstr00036768 | ||||||||
| Construct_product | WBCnstr00007804 | ||||||||
| WBCnstr00007805 | |||||||||
| WBCnstr00010003 | |||||||||
| WBCnstr00036768 | |||||||||
| Antibody | WBAntibody00000624 | ||||||||
| WBAntibody00000631 | |||||||||
| WBAntibody00000632 | |||||||||
| WBAntibody00000783 | |||||||||
| WBAntibody00001312 | |||||||||
| WBAntibody00001392 | |||||||||
| Microarray_results (17) | |||||||||
| Expression_cluster (123) | |||||||||
| Interaction (82) | |||||||||
| WBProcess | WBbiopr:00000017 | ||||||||
| Map_info | Map | III | Position | -0.210379 | Error | 0.001277 | |||
| Positive | Positive_clone | F22B7 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference (69) | |||||||||
| Remark | Sequence connection from [Ahringer JA] | ||||||||
| Gene renamed from ags-3.2 to gpr-1 following advice from [Hodgkin J], [020808 krb] | |||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
