WormBase Tree Display for Expr_pattern: Expr10765
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| Expr10765 | Expression_of | Gene | WBGene00001689 | |
|---|---|---|---|---|
| WBGene00001688 | ||||
| Reflects_endogenous_expression_of | WBGene00001688 | |||
| WBGene00001689 | ||||
| Expression_data | Anatomy_term | WBbt:0008590 | Certain | |
| GO_term | GO:0005818 | |||
| GO:0005938 | ||||
| Subcellular_localization | In early wild-type embryos, GPR-1/2 were localized both on the asters and the cell cortex. The cortical localization of GPR- 1/2 changed with the cell cycle. In one-cell embryos, GPR-1/2 were uniformly present at a low level on the cortex from early prophase to metaphase. The level of cortical localization of GPR-1/2 increased and became weakly enriched at the posterior pole of most embryos during anaphase. In some embryos with enriched posterior staining, GPR-1/2 also appeared to be slightly enriched at the anterior pole of the embryo, compared with lateral regions. GPR-1/2 asymmetry became more pronounced during cytokinesis and interphase of the two-cell stage. In the P1 blastomere during interphase, GPR-1/2 were highly enriched around the posterior pole of the cell, and were present at low levels uniformly around the cortex of AB. As the cell cycle progressed, GPR-1/2 asymmetry in P1 disappeared; GPR-1/2 were uniformly localized around the cortex through out prophase, metaphase and early anaphase. During late anaphase and telophase, GPR-1/2 were once again enriched at the posterior part of the P1 cell. These results indicate that GPR- 1/2 is asymmetrically localized in the P lineage. | |||
| Type | Antibody | |||
| Reference | WBPaper00006289 | |||
| Antibody_info | WBAntibody00000701 |
