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WormBase Tree Display for Gene: WBGene00001565

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Name Class

WBGene00001565EvidenceCGC_data_submission
SMapS_parentSequenceC14B9
IdentityVersion1
NameCGC_namegei-8Person_evidenceWBPerson1796
Sequence_nameC14B9.6
Molecular_nameC14B9.6a
C14B9.6a.1
CE42991
C14B9.6c
CE48463
C14B9.6c.1
Other_namepqn-12
CELE_C14B9.6Accession_evidenceNDBBX284603
Public_namegei-8
DB_infoDatabaseAceViewgene3J202
WormQTLgeneWBGene00001565
WormFluxgeneWBGene00001565
NDBlocus_tagCELE_C14B9.6
PanthergeneCAEEL|WormBase=WBGene00001565|UniProtKB=P34333
familyPTHR13992
NCBIgene176145
RefSeqproteinNM_171207.9
NM_066372.8
SwissProtUniProtAccP34333
UniProt_GCRPUniProtAccP34333
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:24WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classgei
Allele (118)
StrainWBStrain00036421
WBStrain00036659
RNASeq_FPKM (74)
GO_annotation00041711
00041712
00041713
00041714
00041715
00041716
00041717
Ortholog (23)
Structured_descriptionConcise_descriptiongei-8 encodes a novel protein highly similar to C. briggsae BP:CBP04038 that contains a glutamine/asparagine (Q/N)-rich ('prion') domain (by the algorithm of Michelitsch and Weissman) and two myb-like DNA-binding domains; interacts with GEX-3 in yeast two-hybrid assays.Paper_evidenceWBPaper00005068
WBPaper00005194
WBPaper00012788
WBPaper00012830
WBPaper00012882
WBPaper00012897
WBPaper00013003
Curator_confirmedWBPerson48
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionPredicted to enable DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in several structures, including anal depressor muscle; egg-laying apparatus; germ line; somatic nervous system; and tail ganglion. Human ortholog(s) of this gene implicated in Huntington's disease. Is an ortholog of human NCOR1 (nuclear receptor corepressor 1).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:12858Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:7672)
Molecular_infoCorresponding_CDSC14B9.6a
C14B9.6c
Corresponding_CDS_historyC14B9.6a:wp126
C14B9.6a:wp194
C14B9.6b:wp126
C14B9.6b:wp194
C14B9.6b:wp238
C14B9.6c:wp126
C14B9.6c:wp194
C14B9.6c:wp238
Corresponding_transcriptC14B9.6a.1
C14B9.6c.1
Other_sequenceCJC01035_1
Oden_isotig08996
Associated_featureWBsf667130
WBsf667131
WBsf667132
WBsf667133
WBsf717939
WBsf993243
WBsf993244
WBsf1015359
WBsf227081
Transcription_factorWBTranscriptionFactor000765
Experimental_infoRNAi_result (15)
Expr_pattern (9)
Drives_constructWBCnstr00017732
WBCnstr00017733
WBCnstr00017734
WBCnstr00036857
Construct_productWBCnstr00016611
WBCnstr00021812
WBCnstr00036857
Regulate_expr_clusterWBPaper00042128:gei-8(ok1671)_downregulated
WBPaper00042128:gei-8(ok1671)_upregulated
Microarray_results (37)
Expression_clusterWBPaper00033065:cyc-1(RNAi)_downregulated
WBPaper00036375:enriched_in_PVD_OLL
WBPaper00037055:DAF-16_binding_DNA
WBPaper00037950:AVA-neuron_L1-larva_expressed
WBPaper00037950:GABAergic-motor-neurons_L1-larva_expressed
WBPaper00037950:intestine_L1-larva_expressed
WBPaper00040221:DAF-12_target_ALF4
WBPaper00044426:rotenone_24h_downregulated
WBPaper00044616:alg-3-4_downregulated_gene
WBPaper00044736:flat_dev_expression
WBPaper00045420:fertilization_downregulated_transcript
WBPaper00045521:Spermatogenic
WBPaper00046497:B.thuringiensis_0.1mix_downregulated_12h
WBPaper00046497:B.thuringiensis_0.5mix_downregulated_12h
WBPaper00048988:neuron_expressed
WBPaper00049545:jmjd-3.1(+)_upregulated
WBPaper00049545:rgef-1p-jmjd-1.2(+)_upregulated
WBPaper00049920:Glucose-Diet_downregulated_hyl-2(tm2031)
WBPaper00049942:hsf-1(RNAi)_upregulated
WBPaper00050015:ifg-1(RNAi)_upregulated
WBPaper00050094:mes-2(bn11)_upregulated
WBPaper00050094:mes-6(bn66)_upregulated
WBPaper00050344:ASER-neuron_enriched
WBPaper00050488:adult_vs_dauer_regulated_N2_20C
WBPaper00050488:N2_vs_mir-34(OverExpression)_regulated_dauer_20C
WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
WBPaper00050859:upregulated_pgl-1(ct131)_vs_control_day1-adult
WBPaper00050990:arcade_intestinal-valve_expressed
WBPaper00050990:GABAergic-neuron_expressed
WBPaper00050990:hypodermis_expressed
WBPaper00051039:germline_enriched
WBPaper00051265:F4_hrde-1(tm1200)_upregulated
WBPaper00051265:F4_morc-1(tm6048)_upregulated
WBPaper00051558:fog-2(q71)_regulated
WBPaper00053321:embryo-to-L1_upregulated_nos-1(gv5)nos-2(RNAi)_SMARTseq
WBPaper00053321:lin-15B(RNAi)_downregulated_starved-L1_Truseq
WBPaper00053321:nos-1(gv5)nos-2(RNAi)_upregulated_fed-L1_Truseq
WBPaper00053321:nos-1(gv5)nos-2(RNAi)_upregulated_L1_SMARTseq
WBPaper00053321:nos-1(gv5)nos-2(RNAi)_upregulated_starved-L1_Truseq
WBPaper00053321:PGCs_depleted_NuGen
WBPaper00053599:mitosis_vs_meiosis_downregulated
WBPaper00053599:oocyte_vs_mitosis_downregulated
WBPaper00053810:daf-2(e1370)_upregulated
WBPaper00055334:DLC-1_interacting
WBPaper00055354:Rifampicin-Allantoin_downregulated
WBPaper00055648:sperm_expressed
WBPaper00055804:FBF-1-FBF-2-associated_spermatogenic-enriched
WBPaper00055862:antimycin_damt-1(gk961032)_regulated
WBPaper00055971:nhl-2(ok818)_20C_upregulated
WBPaper00055971:nhl-2(ok818)_25C_upregulated
WBPaper00056161:male_enriched_siRNA
WBPaper00056218:daf-16(mu86)_upregulated_Day7
WBPaper00056471:aak-1(tm1944);aak-2(ok524)_upregulated
WBPaper00056471:S.aureus-4h_upregulated_N2
WBPaper00056855:his-72(uge40)_upregulated
WBPaper00057288:iff-1(RNAi)_downregulated_transcript
WBPaper00058725:sftb-1(cer6)_downregulated
WBPaper00058969:RIS_enriched
WBPaper00059027:neuron-synapses_depleted
WBPaper00059356:BAZ-2_SET-6_interacting
WBPaper00059440:GLP-1_represseded
WBPaper00059440:LAG-1_repressed_48hr-auxin
WBPaper00059471:EGL-43_interacting
WBPaper00060100:SiNP_upregulated_mRNA
WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
WBPaper00060661:sensory-neuron_enriched
WBPaper00060811:L1_vs_adult_upregulated_neural
WBPaper00061340:Z1_Z4
WBPaper00061439:unc-30(ok613)_downregulated
WBPaper00061478:SUMO-conjugated_protein
WBPaper00061527:npp-8_4355-afd-1_4796
WBPaper00061527:pkn-1_20439-tbc-12_11015
WBPaper00061527:utx-1_2886-swan-1_2192
WBPaper00062193:skn-1(RNAi)_downregulated
WBPaper00064088:Day-1-adult_vs_L4_upregulated_fem-3(q20)
WBPaper00064088:Day-3-adult_vs_L4_upregulated_fem-3(q20)
WBPaper00064107:lin-35(n745)_downregulated
WBPaper00064315:mes-3(bn199)_upregulated_EGCs
WBPaper00064315:mes-4(bn73)_upregulated_EGCs
WBPaper00064315:mrg-1(qa6200)_upregulated_PGCs
WBPaper00065975:P-body_vs_WholeAnimal_enriched
WBPaper00066085:hda-3(ok1991)_upregulated
cgc4386_cluster_6_5
WBPaper00025141:N2_Expressed_Genes
WBPaper00025141:unc-4::GFP_Expressed_Genes
WBPaper00026929:Resveratrol_regulated_daf-16
WBPaper00026929:sir-2.1_overexpression_regulated
WBPaper00030985:Photorhabdus_luminescens_downregulated
WBPaper00031003:24hr_muscle_depleted
WBPaper00031003:hlh_1_enriched
WBPaper00031003:total_muscle_depleted
WBPaper00031252:AIN-1_IP_enriched
WBPaper00031832:slr-2_regulated
WBPaper00032948:StarveUp2
WBPaper00034661:AgNPs_downregulated
WBPaper00034739:N2lessDR1350
WBPaper00035084:L3_enriched_AIN-2_IP
WBPaper00037695:WC_5-day
WBPaper00040210:Chlorpyrifos_Diazinon_24C_regulated
WBPaper00040603:tdp-1(lf)_up_vs_N2_FC_1.2
WBPaper00040821:Au-NP_regulated
WBPaper00040858:eQTL_age_regulated_aging
WBPaper00040858:eQTL_age_regulated_developing
WBPaper00040858:eQTL_regulated_old
WBPaper00040963:Q100_down
WBPaper00040963:Q200_down
WBPaper00040985:AIN-2_asynchronous_muscle
WBPaper00041002:HQ_3d_0.2mM_Down
WBPaper00041002:HQ_3d_2.0mM_Down
WBPaper00041606:CE_X.nematophila_regulated
WBPaper00041939:control_vs_UVC-EtBr-exposed_24h
WBPaper00041939:EtBr-exposed_vs_UVC-exposed_48h
WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_24h
WBPaper00042274:tbx-2(bx59)_downregulated
WBPaper00042331:a-SWCNTs_downregulated
WBPaper00042548:miRISC_enriched
WBPaper00045263:0.1mM-paraquat_upregulated
WBPaper00045960:L4-lethargus_downregulated
WBPaper00048989:eat-2(ad465)_rapamycin_downregulated
WBPaper00053236:Starvation_regulated_N2
[cgc5767]:expression_class_E
[cgc5767]:expression_class_E_pi(143_min)
[cgc5767]:expression_class_SE
[cgc5767]:expression_class_SE_pi(143_min)
Interaction (34)
Map_infoMapIIIPosition-0.376759Error0.000149
PositivePositive_cloneC14B9Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
Reference (11)
RemarkSequence connection from [Qadota H, Kaibuchi K]
The pqn-12 gene was merged into this gene following advice from [Hodgkin J]. gei-8 was previously attached to C14B9.5 but this sequence was then merged into C14B9.6 to create a splice variant and this change has led to the two gene names being merged. [020621 krb]
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene