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WormBase Tree Display for Gene: WBGene00001553

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Name Class

WBGene00001553SMapS_parentSequenceCHROMOSOME_V
IdentityVersion1
NameCGC_namegcy-33Person_evidenceWBPerson655
Sequence_nameF57F5.2
Molecular_nameF57F5.2a
F57F5.2a.1
CE34891
F57F5.2b
CE45798
F57F5.2c
CE20887
F57F5.2b.1
F57F5.2c.1
Other_nameCeGC4Paper_evidenceWBPaper00003629
CELE_F57F5.2Accession_evidenceNDBBX284605
Public_namegcy-33
DB_infoDatabase (12)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:24WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classgcy
Allele (70)
Legacy_information[Yu S] gcy for Guanylyl CYclase. No mutations known. gcy-33::GFP expressed in sensory neuron BAG. Predicted gene F57F5.2
StrainWBStrain00040612
WBStrain00005388
RNASeq_FPKM (74)
GO_annotation (30)
Ortholog (48)
Paralog (36)
Structured_descriptionConcise_descriptiongcy-33 encodes a soluble guanylate cyclase beta subunit; GCY-33 activity is required in the ciliated BAG head sensory neurons to sense decreases in O2 levels and effect corresponding behavioral changes; a gcy-33::GFP reporter is expressed in the BAG neurons; biochemical characterization of chimeric molecules containing the GCY-33 N-terminal H-NOX domain fused to the rat beta1 guanylate cyclase indicate that the GCY-33 H-NOX domain can form complexes with NO, CO, and O2 and that binding can positively regulate catalytic activity of the molecule.Paper_evidenceWBPaper00002839
WBPaper00002846
WBPaper00033008
WBPaper00038328
Curator_confirmedWBPerson1843
Date_last_updated24 Aug 2011 00:00:00
Automated_descriptionEnables carbon monoxide sensor activity; nitric oxide binding activity; and oxygen sensor activity. Involved in chemosensory behavior; response to oxygen levels; and sensory perception of bitter taste. Predicted to be located in cytoplasm. Predicted to be part of guanylate cyclase complex, soluble. Expressed in oxygen sensory neurons.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSF57F5.2a
F57F5.2b
F57F5.2c
Corresponding_CDS_historyF57F5.2:wp106
Corresponding_transcriptF57F5.2a.1
F57F5.2b.1
F57F5.2c.1
Associated_featureWBsf653177
WBsf669442
WBsf982009
WBsf1001500
WBsf1020525
WBsf234607
WBsf234608
Experimental_infoRNAi_resultWBRNAi00033041Inferred_automaticallyRNAi_primary
WBRNAi00048884Inferred_automaticallyRNAi_primary
WBRNAi00082700Inferred_automaticallyRNAi_primary
WBRNAi00015898Inferred_automaticallyRNAi_primary
WBRNAi00082390Inferred_automaticallyRNAi_primary
Expr_patternExpr237
Expr11512
Expr12107
Expr13051
Expr1024799
Expr1030927
Expr1152629
Expr2011994
Expr2030231
Drives_construct (11)
Construct_productWBCnstr00019054
WBCnstr00036867
Microarray_results (22)
Expression_cluster (118)
Interaction (15)
WBProcessWBbiopr:00000118
Map_infoMapVPosition3.57195Error0.001108
PositivePositive_cloneF57F5Person_evidenceWBPerson4049
Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_dataMulti_point4340
Pseudo_map_position
Reference (34)
RemarkData extracted from Yu et al. (1997)
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene