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WormBase Tree Display for Gene: WBGene00001553

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Name Class

WBGene00001553SMapS_parentSequenceCHROMOSOME_V
IdentityVersion1
NameCGC_namegcy-33Person_evidenceWBPerson655
Sequence_nameF57F5.2
Molecular_nameF57F5.2a
F57F5.2a.1
CE34891
F57F5.2b
CE45798
F57F5.2c
CE20887
F57F5.2b.1
F57F5.2c.1
Other_nameCeGC4Paper_evidenceWBPaper00003629
CELE_F57F5.2Accession_evidenceNDBBX284605
Public_namegcy-33
DB_infoDatabase (12)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:24WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classgcy
Allele (70)
Legacy_information[Yu S] gcy for Guanylyl CYclase. No mutations known. gcy-33::GFP expressed in sensory neuron BAG. Predicted gene F57F5.2
StrainWBStrain00040612
WBStrain00005388
RNASeq_FPKM (74)
GO_annotation (30)
Ortholog (48)
Paralog (36)
Structured_descriptionConcise_descriptiongcy-33 encodes a soluble guanylate cyclase beta subunit; GCY-33 activity is required in the ciliated BAG head sensory neurons to sense decreases in O2 levels and effect corresponding behavioral changes; a gcy-33::GFP reporter is expressed in the BAG neurons; biochemical characterization of chimeric molecules containing the GCY-33 N-terminal H-NOX domain fused to the rat beta1 guanylate cyclase indicate that the GCY-33 H-NOX domain can form complexes with NO, CO, and O2 and that binding can positively regulate catalytic activity of the molecule.Paper_evidenceWBPaper00002839
WBPaper00002846
WBPaper00033008
WBPaper00038328
Curator_confirmedWBPerson1843
Date_last_updated24 Aug 2011 00:00:00
Automated_descriptionEnables carbon monoxide sensor activity; nitric oxide binding activity; and oxygen sensor activity. Involved in chemosensory behavior; response to oxygen levels; and sensory perception of bitter taste. Predicted to be located in cytoplasm. Predicted to be part of guanylate cyclase complex, soluble. Expressed in oxygen sensory neurons.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSF57F5.2a
F57F5.2b
F57F5.2c
Corresponding_CDS_historyF57F5.2:wp106
Corresponding_transcriptF57F5.2a.1
F57F5.2b.1
F57F5.2c.1
Associated_featureWBsf653177
WBsf669442
WBsf982009
WBsf1001500
WBsf1020525
WBsf234607
WBsf234608
Experimental_infoRNAi_resultWBRNAi00033041Inferred_automaticallyRNAi_primary
WBRNAi00048884Inferred_automaticallyRNAi_primary
WBRNAi00082700Inferred_automaticallyRNAi_primary
WBRNAi00015898Inferred_automaticallyRNAi_primary
WBRNAi00082390Inferred_automaticallyRNAi_primary
Expr_patternExpr237
Expr11512
Expr12107
Expr13051
Expr1024799
Expr1030927
Expr1152629
Expr2011994
Expr2030231
Drives_construct (11)
Construct_productWBCnstr00019054
WBCnstr00036867
Microarray_results (22)
Expression_cluster (118)
Interaction (15)
WBProcessWBbiopr:00000118
Map_infoMapVPosition3.57195Error0.001108
PositivePositive_cloneF57F5Person_evidenceWBPerson4049
Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_dataMulti_point4340
Pseudo_map_position
Reference (34)
Remark (2)
MethodGene