WormBase Tree Display for Gene: WBGene00001519

WBGene00001519 SMap: S_parent: Sequence: CHROMOSOME_V
  Identity: Version: 1
    Name: CGC_name: gar-3 Person_evidence: WBPerson32
      Sequence_name: Y40H4A.1
      Molecular_name: Y40H4A.1a
        Y40H4A.1a.1
        CE27783
        Y40H4A.1b
        CE35800
        Y40H4A.1a.2
        Y40H4A.1a.3
        Y40H4A.1b.1
      Other_name: acm-3
        gar-3a Accession_evidence: EMBL AY221631
        CELE_Y40H4A.1 Accession_evidence: NDB BX284605
      Public_name: gar-3
    DB_info: Database (11)
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:24 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: gar
    Allele: WBVar01463004
      WBVar01872581
      WBVar01872397
      WBVar01872582
      WBVar01463005
      WBVar01872398
      WBVar01872583
      WBVar01872399
      WBVar01463006
      WBVar01872400
      WBVar01872584
      WBVar01463007
      WBVar01463008
      WBVar01872585
      WBVar01872401
      WBVar00253763
      WBVar01872402
      WBVar01463009
      WBVar01872586
      WBVar01872403
      WBVar01872587
      WBVar01463010
      WBVar02151798
      WBVar01463011
      WBVar01872588
      WBVar02137576
      WBVar01872404
      WBVar01872589
      WBVar01463012
      WBVar01872405
      WBVar02137577
      WBVar01872406
      WBVar01872590
      WBVar01872591
      WBVar01872407
      WBVar01872408
      WBVar01872592
      WBVar01872409
      WBVar01872593
      WBVar01872410
      WBVar01497688
      WBVar01872594
      WBVar01872595
      WBVar01872411
      WBVar01872412
      WBVar01872596
      WBVar01872597
      WBVar01872413
      WBVar01872414
      WBVar01872598
      WBVar01872415
      WBVar01872599
      WBVar01872600
      WBVar01872416
      WBVar01872601
      WBVar01872417
      WBVar01872602
      WBVar01872418
      WBVar01872603
      WBVar01872419
      WBVar01872604
      WBVar01872420
      WBVar01872605
      WBVar01872421
      WBVar01872422
      WBVar01872606
      WBVar01872423
      WBVar01872607
      WBVar01872608
      WBVar01872424
      WBVar01872609
      WBVar01872425
      WBVar01872426
      WBVar01872610
      WBVar01872427
      WBVar01872611
      WBVar01872612
      WBVar01872428
      WBVar01872429
      WBVar01872613
      WBVar01872614
      WBVar01872430
      WBVar00297674
      WBVar01872615
      WBVar01872431
      WBVar00297675
      WBVar01872432
      WBVar01872616
      WBVar01872433
      WBVar01872617
      WBVar01872618
      WBVar01872434
      WBVar01872619
      WBVar01872435
      WBVar01872620
      WBVar01872436
      WBVar01872437
      WBVar01872621
      WBVar00253246
      WBVar02054907
      WBVar01872438
      WBVar01872622
      WBVar01872623
      WBVar00260427
      WBVar01872439
      WBVar01872624
      WBVar01872440
      WBVar01872441
      WBVar01872625
      WBVar01872442
      WBVar01872626
      WBVar01872443
      WBVar02031973
      WBVar01872627
      WBVar01872444
      WBVar01872628
      WBVar01872629
      WBVar01872445
      WBVar01872630
      WBVar01872446
      WBVar01872447
      WBVar01872631
      WBVar01872632
      WBVar01872448
      WBVar01872449
      WBVar01872633
      WBVar01872450
      WBVar01872634
      WBVar01872635
      WBVar01872451
      WBVar01872636
      WBVar00216283
      WBVar01872452
      WBVar01872637
      WBVar01872453
      WBVar00088493
      WBVar01872638
      WBVar01872454
      WBVar01872639
      WBVar01872455
      WBVar01872640
      WBVar01872456
      WBVar01872641
      WBVar01872457
      WBVar01872458
      WBVar01872642
      WBVar01872643
      WBVar01872459
      WBVar01872460
      WBVar01872644
      WBVar01872461
      WBVar01872645
      WBVar01872646
      WBVar01872462
      WBVar01872463
      WBVar01872647
      WBVar01872648
      WBVar00264684
      WBVar01872464
      WBVar01872649
      WBVar01872465
      WBVar01872466
      WBVar01872650
      WBVar01872467
      WBVar01872651
      WBVar00016420
      WBVar01872468
      WBVar01590459
      WBVar00145712
      WBVar01872652
      WBVar01872653
      WBVar01872469
      WBVar01872654
      WBVar01872470
      WBVar01872655
      WBVar00016425
      WBVar01872471
      WBVar01872472
      WBVar01872656
      WBVar00016430
      WBVar01872473
      WBVar01872657
      WBVar01975473
      WBVar01872474
      WBVar01975474
      WBVar01872658
      WBVar01975475
      WBVar01872475
      WBVar01872659
      WBVar01872660
      WBVar01975476
      WBVar01872476
      WBVar01710419
      WBVar00016435
      WBVar01872661
      WBVar01975477
      WBVar01872477
      WBVar01872662
      WBVar01872478
      WBVar01872479
      WBVar00016440
      WBVar01872663
      WBVar01068392
      WBVar01872480
      WBVar01872664
      WBVar01068393
      WBVar01872481
      WBVar01872665
      WBVar00016445
      WBVar01068394
      WBVar01872482
      WBVar01494816
      WBVar01872666
      WBVar01068395
      WBVar01872667
      WBVar01872483
      WBVar01068396
      WBVar01872668
      WBVar01872484
      WBVar01490218
      WBVar01872669
      WBVar01872485
      WBVar00016450
      WBVar01068397
      WBVar01068398
      WBVar01872486
      WBVar01872670
      WBVar01068399
      WBVar01872487
      WBVar01872671
      WBVar00016455
      WBVar01872672
      WBVar01068400
      WBVar01872488
      WBVar02115722
      WBVar01872673
      WBVar01068401
      WBVar01872489
      WBVar01872490
      WBVar01872674
      WBVar02115723
      WBVar01068402
      WBVar01872491
      WBVar02115724
      WBVar01872675
      WBVar01068403
      WBVar00016460
      WBVar02115725
      WBVar01872676
      WBVar01872492
      WBVar01068404
      WBVar01872677
      WBVar01872493
      WBVar02115726
      WBVar01068405
      WBVar01068406
      WBVar00016465
      WBVar02115727
      WBVar01872494
      WBVar01872678
      WBVar01872679
      WBVar01068407
      WBVar02115728
      WBVar02078909
      WBVar01872495
      WBVar01068408
      WBVar01872680
      WBVar02115729
      WBVar00277709
      WBVar01872496
      WBVar01872497
      WBVar01872681
      WBVar00016470
      WBVar02115730
      WBVar01068409
      WBVar01068410
      WBVar01872498
      WBVar01872682
      WBVar02115731
      WBVar01872499
      WBVar01872683
      WBVar01068411
      WBVar02115732
      WBVar00145744
      WBVar01872684
      WBVar01068412
      WBVar01872500
      WBVar00016475
      WBVar02115733
      WBVar01068413
      WBVar02115734
      WBVar01872685
      WBVar01872501
      WBVar02079288
      WBVar01499621
      WBVar01872502
      WBVar01068414
      WBVar01872686
      WBVar02115735
      WBVar01872503
      WBVar02115736
      WBVar00016480
      WBVar01068415
      WBVar01872687
      WBVar01872688
      WBVar02115737
      WBVar00265276
      WBVar01068416
      WBVar01872504
      WBVar00265277
      WBVar01872689
      WBVar01068417
      WBVar02115738
      WBVar01872505
      WBVar01068418
      WBVar00016485
      WBVar02115739
      WBVar01872506
      WBVar01872690
      WBVar01068419
      WBVar01872507
      WBVar02062365
      WBVar01872691
      WBVar02115740
      WBVar02062366
      WBVar00016490
      WBVar01872508
      WBVar01068420
      WBVar01872692
      WBVar02115741
      WBVar02062367
      WBVar02115742
      WBVar01872509
      WBVar01068421
      WBVar01872693
      WBVar01872694
      WBVar02062368
      WBVar01872510
      WBVar01068422
      WBVar02115743
      WBVar01872511
      WBVar02062369
      WBVar00016495
      WBVar01068423
      WBVar02115744
      WBVar01872695
      WBVar01872696
      WBVar02115745
      WBVar01872512
      WBVar01068424
      WBVar02062370
      WBVar01068425
      WBVar00016500
      WBVar02115746
      WBVar01872513
      WBVar02062371
      WBVar01068426
      WBVar02115747
      WBVar01872514
      WBVar02062372
      WBVar02062373
      WBVar01872515
      WBVar02115748
      WBVar01068427
      WBVar02062374
      WBVar01872516
      WBVar02115749
      WBVar01068428
      WBVar02062375
      WBVar01872517
      WBVar02115750
      WBVar01068429
      WBVar01872518
      WBVar02062376
      WBVar01068430
      WBVar02115751
      WBVar02062377
      WBVar01068431
      WBVar01872519
      WBVar02115752
      WBVar01068432
      WBVar01872520
      WBVar02062378
      WBVar01068433
      WBVar02062379
      WBVar01872521
      WBVar01068434
      WBVar01872522
      WBVar02062380
      WBVar01872523
      WBVar01068435
      WBVar02062381
      WBVar01872524
      WBVar01068436
      WBVar02062382
      WBVar01872525
      WBVar01068437
      WBVar02062383
      WBVar02062384
      WBVar01872526
      WBVar01068438
      WBVar02062385
      WBVar01872527
      WBVar01068439
      WBVar02062386
      WBVar01872528
      WBVar01068440
      WBVar02062387
      WBVar01872529
      WBVar01068441
      WBVar02156621
      WBVar01872530
      WBVar02062388
      WBVar01068442
      WBVar01872531
      WBVar01068443
      WBVar02062389
      WBVar01068444
      WBVar02062390
      WBVar01872532
      WBVar01068445
      WBVar01872533
      WBVar01068446
      WBVar01872534
      WBVar01068447
      WBVar01872535
      WBVar00477190
      WBVar01872536
      WBVar00477191
      WBVar01068448
      WBVar01872537
      WBVar00477192
      WBVar01068449
      WBVar00477193
      WBVar01068450
      WBVar01872538
      WBVar01498921
      WBVar00477194
      WBVar01068451
      WBVar01498922
      WBVar01872539
      WBVar01068452
      WBVar00477195
      WBVar01872540
      WBVar02090929
      WBVar01500212
      WBVar00477196
      WBVar01800131
      WBVar01068453
      WBVar01872541
      WBVar01500213
      WBVar01872542
      WBVar01068454
      WBVar00477197
      WBVar01775385
      WBVar01744468
      WBVar01068455
      WBVar01775386
      WBVar00477198
      WBVar01872543
      WBVar00477199
      WBVar01775387
      WBVar01872544
      WBVar01068456
      WBVar01872545
      WBVar01068457
      WBVar00477200
      WBVar01775388
      WBVar02024628
      WBVar01068458
      WBVar00477201
      WBVar01775389
      WBVar01872546
      WBVar01872547
      WBVar00477202
      WBVar01068459
      WBVar01499299
      WBVar01872548
      WBVar01068460
      WBVar00477203
      WBVar00477204
      WBVar01068461
      WBVar01872549
      WBVar01068462
      WBVar01843066
      WBVar01872550
      WBVar00477205
      WBVar01872551
      WBVar01068463
      WBVar01843067
      WBVar00477206
      WBVar00477207
      WBVar01068464
      WBVar01843068
      WBVar01872552
      WBVar00477208
      WBVar01068465
      WBVar01843069
      WBVar01872553
      WBVar01872554
      WBVar00477209
      WBVar01068466
      WBVar01843070
      WBVar01068467
      WBVar01872555
      WBVar00477210
      WBVar01872556
      WBVar00477211
      WBVar01068468
      WBVar01872557
      WBVar00477212
      WBVar01068469
      WBVar01872558
      WBVar00477213
      WBVar01068470
      WBVar01872375
      WBVar00477214
      WBVar01872559
      WBVar02124257
      WBVar01068471
      WBVar01872560
      WBVar00477215
      WBVar01872376
      WBVar01068472
      WBVar01872377
      WBVar00477216
      WBVar01068473
      WBVar01872561
      WBVar01068474
      WBVar01872562
      WBVar00477217
      WBVar01872378
      WBVar01872379
      WBVar01068475
      WBVar01872563
      WBVar01872564
      WBVar01068476
      WBVar01872380
      WBVar01499316
      WBVar01068477
      WBVar01872381
      WBVar01872565
      WBVar01872382
      WBVar01872566
      WBVar01068478
      WBVar01872567
      WBVar01872383
      WBVar01068479
      WBVar01872568
      WBVar01068480
      WBVar01872384
      WBVar01462992
      WBVar01068481
      WBVar01872569
      WBVar01872385
      WBVar01462993
      WBVar01068482
      WBVar01872386
      WBVar01872570
      WBVar01872571
      WBVar01872387
      WBVar01068483
      WBVar01462994
      WBVar01462995
      WBVar01872572
      WBVar01872388
      WBVar01068484
      WBVar01872389
      WBVar01462996
      WBVar01872573
      WBVar01068485
      WBVar01462997
      WBVar01872390
      WBVar01872574
      WBVar01462998
      WBVar01872575
      WBVar01872391
      WBVar01872392
      WBVar01462999
      WBVar01872576
      WBVar01872577
      WBVar01872393
      WBVar01463000
      WBVar01463001
      WBVar01872394
      WBVar01872578
      WBVar01872579
      WBVar01872395
      WBVar01463002
      WBVar01499698
      WBVar01463003
      WBVar01872396
      WBVar00275109
      WBVar01872580
    Strain: WBStrain00022220
      WBStrain00035957
      WBStrain00035965
      WBStrain00022221
      WBStrain00022222
      WBStrain00052083
    RNASeq_FPKM (74)
    GO_annotation (32)
    Ortholog (57)
    Paralog (17)
    Structured_description: Concise_description: gar-3 encodes a G protein-linked muscarinic acetylcholine receptor; GAR-3 activity is required for regulation of membrane potential and excitation-contraction coupling in pharyngeal muscle and thus, for normal feeding behavior; in regulating pharyngeal pumping, GAR-3 likely acts upstream of GPB-2, a G-protein beta-subunit; GAR-3 also acts cell-autonomously in motor neurons to recruit the SPHK-1 sphingosine kinase to presynaptic acetylcholine release sites; a gar-3::gfp reporter fusion is expressed in the I3 pharyngeal neuron, extrapharyngeal neurons, and in pharyngeal muscles, where expression is highest in the terminal bulb. Paper_evidence: WBPaper00003864
            WBPaper00024250
            WBPaper00041106
          Curator_confirmed: WBPerson1843
          Date_last_updated: 24 Oct 2013 00:00:00
      Automated_description: Enables G protein-coupled acetylcholine receptor activity. Involved in several processes, including G protein-coupled acetylcholine receptor signaling pathway; positive regulation of acetylcholine secretion, neurotransmission; and positive regulation of protein localization to synapse. Located in plasma membrane. Expressed in body wall musculature; linker cell; neurons; non-striated muscle; and somatic nervous system. Human ortholog(s) of this gene implicated in several diseases, including Chagas disease; autoimmune disease of the nervous system (multiple); and lung disease (multiple). Is an ortholog of human CHRM1 (cholinergic receptor muscarinic 1); CHRM3 (cholinergic receptor muscarinic 3); and CHRM5 (cholinergic receptor muscarinic 5). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model (13)
  Molecular_info: Corresponding_CDS: Y40H4A.1a
      Y40H4A.1b
    Corresponding_CDS_history: Y40H4A.1:wp51
    Corresponding_transcript: Y40H4A.1a.1
      Y40H4A.1a.2
      Y40H4A.1a.3
      Y40H4A.1b.1
    Other_sequence (40)
    Associated_feature (16)
  Experimental_info: RNAi_result: WBRNAi00027900 Inferred_automatically: RNAi_primary
      WBRNAi00056336 Inferred_automatically: RNAi_primary
      WBRNAi00092909 Inferred_automatically: RNAi_primary
      WBRNAi00012332 Inferred_automatically: RNAi_primary
      WBRNAi00108394 Inferred_automatically: RNAi_primary
      WBRNAi00020457 Inferred_automatically: RNAi_primary
    Expr_pattern (12)
    Drives_construct: WBCnstr00011074
      WBCnstr00013244
      WBCnstr00013245
      WBCnstr00018255
      WBCnstr00019493
      WBCnstr00036892
    Construct_product: WBCnstr00001301
      WBCnstr00013245
      WBCnstr00018107
      WBCnstr00018108
      WBCnstr00018255
      WBCnstr00036892
    Microarray_results (29)
    Expression_cluster (178)
    Interaction (18)
  Map_info: Map: V Position: 6.49683 Error: 0.009424
    Positive: Positive_clone: Y40H4A Inferred_automatically: From CDS info
            From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 4335
        4959
        5533
    Pseudo_map_position
  Reference (56)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene