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WormBase Tree Display for Gene: WBGene00001496

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Name Class

WBGene00001496SMapS_parentSequenceF25H9
IdentityVersion1
NameCGC_namefrm-10Person_evidenceWBPerson204
Sequence_nameF25H9.5
Molecular_nameF25H9.5a
F25H9.5a.1
CE09662
F25H9.5b
CE45332
F25H9.5b.1
Other_nameCELE_F25H9.5Accession_evidenceNDBBX284605
Public_namefrm-10
DB_infoDatabaseAceViewgene5N947
WormQTLgeneWBGene00001496
WormFluxgeneWBGene00001496
NDBlocus_tagCELE_F25H9.5
PanthergeneCAEEL|WormBase=WBGene00001496|UniProtKB=O02254
familyPTHR13283
NCBIgene179828
RefSeqproteinNM_001269579.3
NM_001269578.4
TREEFAMTREEFAM_IDTF317921
TrEMBLUniProtAccO02254
E1B6U6
UniProt_GCRPUniProtAccO02254
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:24WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classfrm
Allele (59)
RNASeq_FPKM (74)
GO_annotation00008084
00008085
Ortholog (28)
ParalogWBGene00013955Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
Structured_descriptionConcise_descriptionfrm-10 encodes a protein that contains an N-terminal FERM (Band 4.1-ezrin-radixin-moesin) domain; by homology, FRM-10 is predicted to function as a membrane-cytoskeleton linker protein that plays a role in cell adhesion, migration, or organization of cell surface structures; however, as loss of frm-10 activity via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of FRM-10 in C. elegans development and/or behavior is not yet known.Paper_evidenceWBPaper00004651
WBPaper00005654
Curator_confirmedWBPerson1843
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionPredicted to be involved in negative regulation of canonical Wnt signaling pathway. Predicted to be located in plasma membrane. Is an ortholog of human FRMD8 (FERM domain containing 8).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSF25H9.5a
F25H9.5b
Corresponding_transcriptF25H9.5a.1
F25H9.5b.1
Other_sequenceCBC03750_1
CR02018
CJC01301_1
CR09148
CJC16111_1
CRC01510_1
Hbac_isotig05989
CR11055
Associated_featureWBsf647460
WBsf662027
WBsf1001824
WBsf232781
WBsf232782
Experimental_infoRNAi_result (11)
Expr_patternExpr1020045
Expr1030897
Expr1149479
Expr2011882
Expr2030120
Drives_constructWBCnstr00036910
Construct_productWBCnstr00036910
Microarray_results (22)
Expression_clusterWBPaper00031040:TGF-beta_adult_downregulated
WBPaper00033065:cyc-1(RNAi)_upregulated
WBPaper00035269:cde-1_regulated
WBPaper00037950:all-neurons_L1-larva_expressed
WBPaper00037950:all-neurons_L2-larva_expressed
WBPaper00040221:DAF-12_target_ALF4
WBPaper00044030:nhr-8(hd117)_upregulated
WBPaper00044736:flat_dev_expression
WBPaper00045521:Oogenic
WBPaper00048923:Aging_regulated
WBPaper00048988:neuron_expressed
WBPaper00049018:ham-3(RNAi)_downregulated
WBPaper00050344:AFD-neuron_enriched
WBPaper00050488:20C_vs_25C_regulated_mir-34(gk437)_adult
WBPaper00050488:20C_vs_25C_regulated_mir-34(OverExpression)_adult
WBPaper00050488:adult_vs_dauer_regulated_N2_20C
WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
WBPaper00050903:mir-35-41(nDf50)_25C_upregulated
WBPaper00050990:body-muscle_expressed
WBPaper00050990:GABAergic-neuron_expressed
WBPaper00050990:hypodermis_expressed
WBPaper00050990:intestine_expressed
WBPaper00050990:pharynx_expressed
WBPaper00051039:ash-2(RNAi)_regulated_intestine
WBPaper00051311:VGLN-1-interacting
WBPaper00051404:alg-5(ram2)_downregulated
WBPaper00053184:sma-2(rax5)_upregulated
WBPaper00053184:sma-4(rax3)_upregulated
WBPaper00053295:lin-22(ot267)_downregulated
WBPaper00053295:lin-22(ot269)_downregulated
WBPaper00053302:stavudine_24h_regulated
WBPaper00053302:stavudine_72h_regulated
WBPaper00053302:zidovudine_72h_regulated
WBPaper00053388:dauer_regulated_Cluster2
WBPaper00053599:female_vs_male_upregulated
WBPaper00053810:nuo-6(qm200)_upregulated
WBPaper00055354:Rapamycin-Rifampicin_upregulated
WBPaper00055354:Rifampicin-Psora_upregulated
WBPaper00055482:pmt-2(RNAi)_upregulated
WBPaper00055565:AVK_enriched
WBPaper00055648:germline_expressed
WBPaper00056161:male_enriched_siRNA
WBPaper00056471:aak-1(tm1944);aak-2(ok524)_upregulated
WBPaper00056471:S.aureus-4h_upregulated_N2
WBPaper00056619:CEPsh_enriched
WBPaper00057288:Cold_upregulated_transcript
WBPaper00058948:PA14_downregulated
WBPaper00059356:BAZ-2_SET-6_interacting
WBPaper00059471:EGL-43_interacting
WBPaper00059537:ngn-1(ok2200)_upregulated
WBPaper00059566:wdr-23(mac32)_upregulated
WBPaper00059763:neuron_expressed
WBPaper00059987:Wounding_upregulated
WBPaper00060084:cco-1(RNAi)_upregulated_N2
WBPaper00060661:sensory-neuron_enriched
WBPaper00060811:L1_vs_adult_upregulated_neural
WBPaper00061340:DA_DB
WBPaper00061439:unc-30(ok613)_downregulated
WBPaper00061439:unc-30(ok613)_downregulated_P.aeruginosa-infection
WBPaper00061466:nath-10(icb99)_upregulated
WBPaper00061527:lst-4_22151-F46F11.6_12556
WBPaper00061651:AVG_enriched
WBPaper00061651:AVH_enriched
WBPaper00061651:DVB_enriched
WBPaper00061651:PLN_enriched
WBPaper00061651:RID_enriched
WBPaper00061651:RMF_enriched
WBPaper00061651:SIA_enriched
WBPaper00061651:SIB_enriched
WBPaper00061651:VB01_enriched
WBPaper00061651:VB02_enriched
WBPaper00061902:camt-1(ok515)_regulated_RMG
WBPaper00062159:hda-2(ok1479)_upregulated
WBPaper00062325:muscle_depleted_coding-RNA
WBPaper00062354:H.zoospora_6h_regulated
WBPaper00064088:Day-3-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
WBPaper00064088:Day-3-adult_vs_L4_upregulated_glp-1(e2141)
WBPaper00064229:B.thuringiensis-Cry5Ba_downregulated
WBPaper00064539:nhr-114(gk849)_upregulated
WBPaper00064939:vit-5(RNAi)_upregulated
WBPaper00065096:Day10_vs_Day1_upregulated
WBPaper00065120:body-muscle-transcriptome
WBPaper00065258:anchor-cell_depleted
WBPaper00065373:Cisplatin_upregulated_WT
WBPaper00066062:xrep-4(lax137)_upregulated
WBPaper00066085:sin-3(syb2172)_downregulated
WBPaper00066085:sin-3(tm1276)_downregulated
cgc4489_group_4
WBPaper00025032:cluster_81
WBPaper00025141:N2_Expressed_Genes
WBPaper00025141:unc-4::GFP_Expressed_Genes
WBPaper00026929:sir-2.1_overexpression_regulated
WBPaper00026980:intestine_enriched
WBPaper00032165:differentially_expressed_with_age_medoid_2
WBPaper00034739:N2moreDR1350
WBPaper00034757:up_by_oxidative_stress
WBPaper00035084:embryo_enriched_AIN-2_IP
WBPaper00035084:L1_enriched_AIN-2_IP
WBPaper00035084:L2_enriched_AIN-2_IP
WBPaper00035084:L3_enriched_AIN-2_IP
WBPaper00035084:L4_enriched_AIN-2_IP
WBPaper00035227:heat_shock_regulated
WBPaper00035905:FBF-1_Associated
WBPaper00036286:Pattern_F
WBPaper00038231:Cry5B_1.5-fold_upregulated
WBPaper00038231:Cry5B_2-fold_upregulated
WBPaper00040963:Q100_down
WBPaper00040963:Q200_down
WBPaper00040963:TA300_down
WBPaper00040985:AIN-2_L4_intestine
WBPaper00041370:spg-7(RNAi)_upregulated
WBPaper00041606:CE_B.thuringiensis-DB27_regulated
WBPaper00041606:CE_X.nematophila_regulated
WBPaper00041939:control_vs_EtBr-exposed_48h
WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
WBPaper00041939:EtBr-exposed_vs_UVC-exposed_48h
WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_48h
WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_51h
WBPaper00045263:0.1mM-paraquat_upregulated
WBPaper00045263:isp-1(qm150)_upregulated
WBPaper00045263:nuo-6(qm200)_upregulated
WBPaper00045263:ProLongevity-mtROS_upregulated
WBPaper00047070:N2_starvation_upregulated
WBPaper00048624:hlh-25(ok1710)_upregulated
WBPaper00053236:Starvation_regulated_GR1307
WBPaper00053236:Starvation_regulated_N2
WBPaper00055899:nitroguanidine_regulated
[cgc5767]:expression_class_M
[cgc5767]:expression_class_SM
[cgc6390]:Cluster_A
[cgc6390]:Cluster_E
[cgc6390]:herm_sex-enriched
InteractionWBInteraction000113516
WBInteraction000150540
WBInteraction000151296
WBInteraction000164719
WBInteraction000165288
WBInteraction000198921
WBInteraction000213063
WBInteraction000214505
WBInteraction000221169
WBInteraction000221876
WBInteraction000232758
WBInteraction000237280
WBInteraction000246006
WBInteraction000246367
WBInteraction000251541
WBInteraction000252397
WBInteraction000256378
WBInteraction000259618
WBInteraction000259696
WBInteraction000260695
WBInteraction000266498
WBInteraction000274018
WBInteraction000274080
WBInteraction000274930
WBInteraction000277756
WBInteraction000279729
WBInteraction000282608
WBInteraction000287713
WBInteraction000292366
WBInteraction000297585
WBInteraction000302488
WBInteraction000326541
WBInteraction000351209
WBInteraction000362208
WBInteraction000367506
WBInteraction000373760
WBInteraction000373853
WBInteraction000375236
WBInteraction000379061
WBInteraction000379307
WBInteraction000389903
WBInteraction000390893
WBInteraction000398637
WBInteraction000404024
WBInteraction000405898
WBInteraction000410954
WBInteraction000420348
WBInteraction000425937
WBInteraction000444843
WBInteraction000452854
WBInteraction000455641
WBInteraction000459637
WBInteraction000560364
Map_infoMapVPosition5.34882Error0.000691
PositivePositive_cloneF25H9Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00024261
WBPaper00038491
WBPaper00055090
Remarkdata submitted by [Gobel V]
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene