WormBase Tree Display for Gene: WBGene00001496

WBGene00001496 SMap: S_parent: Sequence: F25H9
  Identity: Version: 1
    Name: CGC_name: frm-10 Person_evidence: WBPerson204
      Sequence_name: F25H9.5
      Molecular_name: F25H9.5a
        F25H9.5a.1
        CE09662
        F25H9.5b
        CE45332
        F25H9.5b.1
      Other_name: CELE_F25H9.5 Accession_evidence: NDB BX284605
      Public_name: frm-10
    DB_info: Database: AceView gene 5N947
        WormQTL gene WBGene00001496
        WormFlux gene WBGene00001496
        NDB locus_tag CELE_F25H9.5
        Panther gene CAEEL|WormBase=WBGene00001496|UniProtKB=O02254
          family PTHR13283
        NCBI gene 179828
        RefSeq protein NM_001269579.3
            NM_001269578.4
        TREEFAM TREEFAM_ID TF317921
        TrEMBL UniProtAcc O02254
            E1B6U6
        UniProt_GCRP UniProtAcc O02254
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:24 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: frm
    Allele (59)
    RNASeq_FPKM (74)
    GO_annotation: 00008084
      00008085
    Ortholog (28)
    Paralog: WBGene00013955 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
    Structured_description: Concise_description: frm-10 encodes a protein that contains an N-terminal FERM (Band 4.1-ezrin-radixin-moesin) domain; by homology, FRM-10 is predicted to function as a membrane-cytoskeleton linker protein that plays a role in cell adhesion, migration, or organization of cell surface structures; however, as loss of frm-10 activity via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of FRM-10 in C. elegans development and/or behavior is not yet known. Paper_evidence: WBPaper00004651
            WBPaper00005654
          Curator_confirmed: WBPerson1843
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Predicted to be involved in negative regulation of canonical Wnt signaling pathway. Predicted to be located in plasma membrane. Is an ortholog of human FRMD8 (FERM domain containing 8). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: F25H9.5a
      F25H9.5b
    Corresponding_transcript: F25H9.5a.1
      F25H9.5b.1
    Other_sequence: CBC03750_1
      CR02018
      CJC01301_1
      CR09148
      CJC16111_1
      CRC01510_1
      Hbac_isotig05989
      CR11055
    Associated_feature: WBsf647460
      WBsf662027
      WBsf1001824
      WBsf232781
      WBsf232782
  Experimental_info: RNAi_result (11)
    Expr_pattern: Expr1020045
      Expr1030897
      Expr1149479
      Expr2011882
      Expr2030120
    Drives_construct: WBCnstr00036910
    Construct_product: WBCnstr00036910
    Microarray_results (22)
    Expression_cluster: WBPaper00031040:TGF-beta_adult_downregulated
      WBPaper00033065:cyc-1(RNAi)_upregulated
      WBPaper00035269:cde-1_regulated
      WBPaper00037950:all-neurons_L1-larva_expressed
      WBPaper00037950:all-neurons_L2-larva_expressed
      WBPaper00040221:DAF-12_target_ALF4
      WBPaper00044030:nhr-8(hd117)_upregulated
      WBPaper00044736:flat_dev_expression
      WBPaper00045521:Oogenic
      WBPaper00048923:Aging_regulated
      WBPaper00048988:neuron_expressed
      WBPaper00049018:ham-3(RNAi)_downregulated
      WBPaper00050344:AFD-neuron_enriched
      WBPaper00050488:20C_vs_25C_regulated_mir-34(gk437)_adult
      WBPaper00050488:20C_vs_25C_regulated_mir-34(OverExpression)_adult
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050903:mir-35-41(nDf50)_25C_upregulated
      WBPaper00050990:body-muscle_expressed
      WBPaper00050990:GABAergic-neuron_expressed
      WBPaper00050990:hypodermis_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00050990:pharynx_expressed
      WBPaper00051039:ash-2(RNAi)_regulated_intestine
      WBPaper00051311:VGLN-1-interacting
      WBPaper00051404:alg-5(ram2)_downregulated
      WBPaper00053184:sma-2(rax5)_upregulated
      WBPaper00053184:sma-4(rax3)_upregulated
      WBPaper00053295:lin-22(ot267)_downregulated
      WBPaper00053295:lin-22(ot269)_downregulated
      WBPaper00053302:stavudine_24h_regulated
      WBPaper00053302:stavudine_72h_regulated
      WBPaper00053302:zidovudine_72h_regulated
      WBPaper00053388:dauer_regulated_Cluster2
      WBPaper00053599:female_vs_male_upregulated
      WBPaper00053810:nuo-6(qm200)_upregulated
      WBPaper00055354:Rapamycin-Rifampicin_upregulated
      WBPaper00055354:Rifampicin-Psora_upregulated
      WBPaper00055482:pmt-2(RNAi)_upregulated
      WBPaper00055565:AVK_enriched
      WBPaper00055648:germline_expressed
      WBPaper00056161:male_enriched_siRNA
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_upregulated
      WBPaper00056471:S.aureus-4h_upregulated_N2
      WBPaper00056619:CEPsh_enriched
      WBPaper00057288:Cold_upregulated_transcript
      WBPaper00058948:PA14_downregulated
      WBPaper00059356:BAZ-2_SET-6_interacting
      WBPaper00059471:EGL-43_interacting
      WBPaper00059537:ngn-1(ok2200)_upregulated
      WBPaper00059566:wdr-23(mac32)_upregulated
      WBPaper00059763:neuron_expressed
      WBPaper00059987:Wounding_upregulated
      WBPaper00060084:cco-1(RNAi)_upregulated_N2
      WBPaper00060661:sensory-neuron_enriched
      WBPaper00060811:L1_vs_adult_upregulated_neural
      WBPaper00061340:DA_DB
      WBPaper00061439:unc-30(ok613)_downregulated
      WBPaper00061439:unc-30(ok613)_downregulated_P.aeruginosa-infection
      WBPaper00061466:nath-10(icb99)_upregulated
      WBPaper00061527:lst-4_22151-F46F11.6_12556
      WBPaper00061651:AVG_enriched
      WBPaper00061651:AVH_enriched
      WBPaper00061651:DVB_enriched
      WBPaper00061651:PLN_enriched
      WBPaper00061651:RID_enriched
      WBPaper00061651:RMF_enriched
      WBPaper00061651:SIA_enriched
      WBPaper00061651:SIB_enriched
      WBPaper00061651:VB01_enriched
      WBPaper00061651:VB02_enriched
      WBPaper00061902:camt-1(ok515)_regulated_RMG
      WBPaper00062159:hda-2(ok1479)_upregulated
      WBPaper00062325:muscle_depleted_coding-RNA
      WBPaper00062354:H.zoospora_6h_regulated
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_glp-1(e2141)
      WBPaper00064229:B.thuringiensis-Cry5Ba_downregulated
      WBPaper00064539:nhr-114(gk849)_upregulated
      WBPaper00064939:vit-5(RNAi)_upregulated
      WBPaper00065096:Day10_vs_Day1_upregulated
      WBPaper00065120:body-muscle-transcriptome
      WBPaper00065258:anchor-cell_depleted
      WBPaper00065373:Cisplatin_upregulated_WT
      WBPaper00066062:xrep-4(lax137)_upregulated
      WBPaper00066085:sin-3(syb2172)_downregulated
      WBPaper00066085:sin-3(tm1276)_downregulated
      cgc4489_group_4
      WBPaper00025032:cluster_81
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00025141:unc-4::GFP_Expressed_Genes
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00026980:intestine_enriched
      WBPaper00032165:differentially_expressed_with_age_medoid_2
      WBPaper00034739:N2moreDR1350
      WBPaper00034757:up_by_oxidative_stress
      WBPaper00035084:embryo_enriched_AIN-2_IP
      WBPaper00035084:L1_enriched_AIN-2_IP
      WBPaper00035084:L2_enriched_AIN-2_IP
      WBPaper00035084:L3_enriched_AIN-2_IP
      WBPaper00035084:L4_enriched_AIN-2_IP
      WBPaper00035227:heat_shock_regulated
      WBPaper00035905:FBF-1_Associated
      WBPaper00036286:Pattern_F
      WBPaper00038231:Cry5B_1.5-fold_upregulated
      WBPaper00038231:Cry5B_2-fold_upregulated
      WBPaper00040963:Q100_down
      WBPaper00040963:Q200_down
      WBPaper00040963:TA300_down
      WBPaper00040985:AIN-2_L4_intestine
      WBPaper00041370:spg-7(RNAi)_upregulated
      WBPaper00041606:CE_B.thuringiensis-DB27_regulated
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00041939:control_vs_EtBr-exposed_48h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
      WBPaper00041939:EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_51h
      WBPaper00045263:0.1mM-paraquat_upregulated
      WBPaper00045263:isp-1(qm150)_upregulated
      WBPaper00045263:nuo-6(qm200)_upregulated
      WBPaper00045263:ProLongevity-mtROS_upregulated
      WBPaper00047070:N2_starvation_upregulated
      WBPaper00048624:hlh-25(ok1710)_upregulated
      WBPaper00053236:Starvation_regulated_GR1307
      WBPaper00053236:Starvation_regulated_N2
      WBPaper00055899:nitroguanidine_regulated
      [cgc5767]:expression_class_M
      [cgc5767]:expression_class_SM
      [cgc6390]:Cluster_A
      [cgc6390]:Cluster_E
      [cgc6390]:herm_sex-enriched
    Interaction (53)
  Map_info: Map: V Position: 5.34882 Error: 0.000691
    Positive: Positive_clone: F25H9 Inferred_automatically: From CDS info
            From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00024261
    WBPaper00038491
    WBPaper00055090
  Remark: data submitted by [Gobel V]
    Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene