| WBGene00001483 | SMap | S_parent | Sequence | C03C11 |
|---|
| Identity | Version | 1 |
| | Name | CGC_name | fog-3 | Person_evidence | WBPerson261 |
| | | Sequence_name | C03C11.2 |
| | | Molecular_name | C03C11.2 |
| | | | C03C11.2.1 |
| | | | CE07874 |
| | | Other_name | CELE_C03C11.2 | Accession_evidence | NDB | BX284601 |
| | | Public_name | fog-3 |
| | DB_info | Database | AceView | gene | 1K593 |
| | | | WormQTL | gene | WBGene00001483 |
| | | | WormFlux | gene | WBGene00001483 |
| | | | NDB | locus_tag | CELE_C03C11.2 |
| | | | Panther | gene | CAEEL|WormBase=WBGene00001483|UniProtKB=G5EDX7 |
| | | | | family | PTHR17537 |
| | | | NCBI | gene | 172863 |
| | | | RefSeq | protein | NM_060245.6 |
| | | | TrEMBL | UniProtAcc | G5EDX7 |
| | | | UniProt_GCRP | UniProtAcc | G5EDX7 |
| | Species | Caenorhabditis elegans |
| | History | Version_change | 1 | 07 Apr 2004 11:29:24 | WBPerson1971 | Event | Imported | Initial conversion from geneace |
| | Status | Live |
| Gene_info | Biotype | SO:0001217 |
| | Gene_class | fog |
| | Allele (37) |
| | Legacy_information | [C.elegansII] q469 : XX animals transformed into females, XO animals somatically male, make oocytes in germ line. q469/Df similar. No dominant phenotypes. ES3 (adult XX), ME0.OA>10: q441, q443, q470, q520fdi, q502uvp,oz137, oz147. [Ellis and Kimble 1995; RE] |
| | Strain | WBStrain00022550 |
| | | WBStrain00022589 |
| | | WBStrain00022656 |
| | | WBStrain00022661 |
| | | WBStrain00040667 |
| | | WBStrain00004780 |
| | | WBStrain00005668 |
| | | WBStrain00005669 |
| | | WBStrain00048384 |
| | RNASeq_FPKM (74) |
| | GO_annotation (13) |
| | Ortholog (34) |
| | Paralog | WBGene00020380 | Caenorhabditis elegans | From_analysis | WormBase-Compara |
| | Structured_description | Concise_description | fog-3 encodes a protein that has similarity, in its N-terminus, to the vertebrate Tob, BTG1, and BTG2 proteins that function in growth control and/or differentiation; in C. elegans, FOG-3 activity is required in the germ line throughout development for initiation and maintenance of spermatogenesis; fog-3 mRNA is expressed at highest levels in the L3, L4, and young adult stages of development, when spermatogenesis occurs; fog-3 transcription appears to be under the control of TRA-1A, which interacts with predicted TRA-1A binding sites in the fog-3 promoter in vitro. | Paper_evidence | WBPaper00003882 |
| | | | | | WBPaper00004256 |
| | | | | Curator_confirmed | WBPerson1843 |
| | | | | Date_last_updated | 27 Oct 2005 00:00:00 |
| | | Automated_description | Predicted to enable transcription corepressor activity. Involved in cell fate specification; developmental process involved in reproduction; and positive regulation of oocyte development. Located in cytoplasm and nuclear periphery. Expressed in germ line. Is an ortholog of human TOB1 (transducer of ERBB2, 1). | Paper_evidence | WBPaper00065943 |
| | | | | Curator_confirmed | WBPerson324 |
| | | | | | WBPerson37462 |
| | | | | Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase |
| | | | | Date_last_updated | 29 Nov 2023 00:00:00 |
| Molecular_info | Corresponding_CDS | C03C11.2 |
| | Corresponding_transcript | C03C11.2.1 |
| | Other_sequence | AY589605.1 |
| | Associated_feature | WBsf979085 |
| | | WBsf984884 |
| | | WBsf218378 |
| | | WBsf218379 |
| Experimental_info | RNAi_result (11) |
| | Expr_pattern (8) |
| | Drives_construct (15) |
| | Construct_product (16) |
| | Regulate_expr_cluster | WBPaper00048762:FOG-3_associated |
| | | WBPaper00054792:FOG-3_interacting |
| | Microarray_results (19) |
| | Expression_cluster | WBPaper00037950:A-class-motor-neurons_L1-larva_expressed |
| | | WBPaper00037950:all-neurons_L1-larva_expressed |
| | | WBPaper00037950:AVE-neuron_L1-larva_expressed |
| | | WBPaper00037950:bodywall-muscle_L1-larva_expressed |
| | | WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed |
| | | WBPaper00037950:coelomocytes_L1-larva_expressed |
| | | WBPaper00037950:coelomocytes_L2-larva_expressed |
| | | WBPaper00037950:dopaminergic-neurons_L1-larva_expressed |
| | | WBPaper00037950:GABAergic-motor-neurons_L1-larva_expressed |
| | | WBPaper00037950:GABAergic-motor-neurons_L2-larva_expressed |
| | | WBPaper00037950:germline-precursors_blastula-embryo_expressed |
| | | WBPaper00037950:hypodermis_L1-larva_expressed |
| | | WBPaper00037950:intestine_L1-larva_expressed |
| | | WBPaper00037950:pharyngeal-muscle_L1-larva_expressed |
| | | WBPaper00041071:spe-44_upregulated |
| | | WBPaper00042194:nhr-114(RNAi)_upregulated |
| | | WBPaper00042215:wdr-23(tm1817)_upregulated |
| | | WBPaper00042477:rsr-2(RNAi)_upregulated_TilingArray |
| | | WBPaper00044260:nicotinc-acid_upregulated |
| | | WBPaper00044736:flat_dev_expression |
| | | WBPaper00044743:wdr-23_neuron_upregulated |
| | | WBPaper00044760:germline_specific |
| | | WBPaper00045257:bar-1(ga80)_downregulated |
| | | WBPaper00045390:ubc-9(RNAi)_upregulated |
| | | WBPaper00045521:Spermatogenic |
| | | WBPaper00045861:wdr-5(ok1417)_upregulated |
| | | WBPaper00046805:csr-1(RNAi)_upregulated_Set1 |
| | | WBPaper00046805:csr-1(RNAi)_upregulated_Set2 |
| | | WBPaper00048762:FOG-3_associated |
| | | WBPaper00049498:npr-1(ur89)_regulated_1 |
| | | WBPaper00049942:HeatShock_upregulated_hsf-1(RNAi) |
| | | WBPaper00049942:hsf-1(RNAi)_upregulated |
| | | WBPaper00050080:rbr-2(tm3141)_downregulated |
| | | WBPaper00050094:mes-2(bn11)_upregulated |
| | | WBPaper00050231:male_enriched |
| | | WBPaper00050488:adult_vs_dauer_regulated_N2_20C |
| | | WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C |
| | | WBPaper00050726:OsmoticStress_regulated_Food |
| | | WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult |
| | | WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day1-adult |
| | | WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult |
| | | WBPaper00050859:upregulated_pgl-1(ct131)_vs_control_day1-adult |
| | | WBPaper00051265:F4_hrde-1(tm1200)_upregulated |
| | | WBPaper00051265:F4_morc-1(tm6048)_upregulated |
| | | WBPaper00051338:jmjd-5(tm3735)_upregulated_G0 |
| | | WBPaper00052885:hrde-1(tm1200)-emb-4(qm31)_regulated |
| | | WBPaper00053184:sma-4(rax3)_upregulated |
| | | WBPaper00053295:lin-22(icb38)_downregulated |
| | | WBPaper00053321:mes-4(RNAi)_downregulated_fed-L1_Truseq |
| | | WBPaper00053321:PGCs_enriched_NuGen |
| | | WBPaper00053599:female_vs_male_downregulated |
| | | WBPaper00053599:mitosis_vs_meiosis_upregulated |
| | | WBPaper00053810:clk-1(qm30)_downregulated |
| | | WBPaper00053888:drh-3(rrr2)_upregulated |
| | | WBPaper00054493:hpl-2(tm1489)_upregulated |
| | | WBPaper00055013:hmg-3(bar24)_downregulated |
| | | WBPaper00055226:ADR-2_target_adr-1(tm668) |
| | | WBPaper00055226:ADR-2_target_N2 |
| | | WBPaper00055354:Rifampicin_downregulated |
| | | WBPaper00055386:daf-2(e1370)_upregulated |
| | | WBPaper00055482:pmt-2(RNAi)_upregulated |
| | | WBPaper00055648:germline_expressed |
| | | WBPaper00055804:FBF-1-FBF-2-associated_spermatogenic-enriched |
| | | WBPaper00055827:pfd-6(gk493446)_downregulated |
| | | WBPaper00055862:antimycin_damt-1(gk961032)_regulated |
| | | WBPaper00056034:pals-22(jy3)_upregulated |
| | | WBPaper00056034:pals-25(jy9)_upregulated |
| | | WBPaper00056039:ptl-1(ok621)_downregulated |
| | | WBPaper00056161:male_enriched_siRNA |
| | | WBPaper00056167:Cry5B_downregulated |
| | | WBPaper00056290:hsp-6(mg585)_upregulated |
| | | WBPaper00056471:aak-1(tm1944);aak-2(ok524)_upregulated |
| | | WBPaper00056471:flcn-1(ok975)_downregulated |
| | | WBPaper00056997:nmad-1(ok3133)_upregulated_germline_25C |
| | | WBPaper00057196:raga-1(ok386)_downregulated) |
| | | WBPaper00057288:Cold_upregulated_transcript |
| | | WBPaper00057288:iff-1(RNAi)_upregulated_transcript |
| | | WBPaper00058598:mex-1(or286)_downregulated |
| | | WBPaper00058598:sin-3(tm1276)_upregulated |
| | | WBPaper00058711:wdr-5(ok1417)_upregulated |
| | | WBPaper00058725:sftb-1(cer39)_downregulated |
| | | WBPaper00058948:npr-8(ok1439)_downregulated_OP50 |
| | | WBPaper00058948:npr-8(ok1439)_downregulated_PA14 |
| | | WBPaper00058948:PA14_upregulated |
| | | WBPaper00059117:B.subtilis_upregulated |
| | | WBPaper00059421:daf-1(m40);daf-3(mgDf90)_downregulated |
| | | WBPaper00059421:daf-1(m40)_downregulated |
| | | WBPaper00059605:mut-16(pk710)_upregulated |
| | | WBPaper00059605:simr-1(cmp36)_upregulated |
| | | WBPaper00059609:malt-1_ilc-17.1_nfki-1_downregulated |
| | | WBPaper00059728:5ug_cholesterol_upregulated |
| | | WBPaper00059728:20ug_cholesterol_upregulated |
| | | WBPaper00059739:hira-1(gk835598)_downregulated_L4 |
| | | WBPaper00060014:set-2(tm1630)_upregulated |
| | | WBPaper00060358:B.thuringiensis_pathogen_regulated_N2 |
| | | WBPaper00060526:plp-1(ok2155)_upregulated |
| | | WBPaper00060811:L1_vs_adult_downregulated_neural |
| | | WBPaper00060886:spr-5(by101)_upregulated |
| | | WBPaper00060921:tdc-1(n3419)_downregulated |
| | | WBPaper00061203:sin-3(tm1276)_downregulated |
| | | WBPaper00061341:28C_24h_upregulated |
| | | WBPaper00061341:28C_48h_upregulated |
| | | WBPaper00061424:Diet_MYb120_upregulated |
| | | WBPaper00061439:unc-30(ok613)_upregulated |
| | | WBPaper00061478:pie-1(ne4433)_upregulated |
| | | WBPaper00061479:hda-1(ne4752)_upregulated |
| | | WBPaper00061479:mep-1(ne4629)_upregulated |
| | | WBPaper00061479:ubc-9(ne4833)_upregulated |
| | | WBPaper00061527:mlt-9_22518-F33D4.6_14044 |
| | | WBPaper00061613:human-alpha-Synuclein(A53T)_upregulated |
| | | WBPaper00061613:human-amyloid-beta_alpha-Synuclein(A53T)_upregulated |
| | | WBPaper00061653:alh-4(hj221)_downregulated |
| | | WBPaper00061753:csr-1(tor159)_downregulated_25C |
| | | WBPaper00061902:camt-1(ok515)_regulated_RMG |
| | | WBPaper00062156:jmjd-5(zr1234)_upregulated |
| | | WBPaper00062159:hda-2(ok1479)_downregulated |
| | | WBPaper00062325:muscle_depleted_coding-RNA |
| | | WBPaper00062446:nhr-8(hd117)_upregulated |
| | | WBPaper00062585:hlh-26(ok1453)_upregulated_E.faecium |
| | | WBPaper00062672:let-418(n3536)dcp-66(RNAi)_upregulated |
| | | WBPaper00062672:let-418(n3536)_upregulated |
| | | WBPaper00062715:blmp-1(s71)_upregulated |
| | | WBPaper00064088:Day-1-adult_vs_L4_upregulated_fem-3(q20) |
| | | WBPaper00064088:Day-3-adult_vs_L4_upregulated_fem-3(q20) |
| | | WBPaper00064156:lipl-4(overexpress)_upregulated |
| | | WBPaper00064315:mes-3(bn199)_downregulated_PGCs |
| | | WBPaper00064315:mes-4(bn73)_downregulated_PGCs |
| | | WBPaper00064315:mrg-1(qa6200)_downregulated_PGCs |
| | | WBPaper00064509:static-magnetic-field_upregulated |
| | | WBPaper00064539:nhr-114(gk849)_upregulated |
| | | WBPaper00064632:daf-2(e1370)_upregulated_intestine |
| | | WBPaper00064637:cox-5B(RNAi)_upregulated |
| | | WBPaper00064716:paraquat_downregulated |
| | | WBPaper00064769:him-17(me24)_upregulated |
| | | WBPaper00064933:bcf-1(ylf1)_upregulated_transcript |
| | | WBPaper00065005:sams-3(RNAi)_upregulated |
| | | WBPaper00065005:sams-4(RNAi)_upregulated |
| | | WBPaper00065086:JU1400_N.ferruginous_regulated |
| | | WBPaper00065086:N2_N.ferruginous_regulated |
| | | WBPaper00065096:25C_vs_20C_downregulated |
| | | WBPaper00065096:Day10_vs_Day1_downregulated |
| | | WBPaper00065096:npr-8(ok1439)_upregulated_Day1_25C |
| | | WBPaper00065096:npr-8(ok1439)_upregulated_Day10_20C |
| | | WBPaper00065096:npr-8(ok1439)_upregulated_Day10_25C |
| | | WBPaper00065258:anchor-cell_depleted |
| | | WBPaper00065623:144 |
| | | WBPaper00065993:glp-1(e2141)_downregulated |
| | | WBPaper00066038:mip-1(how5)_upregulated |
| | | WBPaper00066062:xrep-4(lax137)_upregulated |
| | | WBPaper00066085:hda-3(ok1991)_upregulated |
| | | WBPaper00066110:Doxorubicin_upregulated_diploid |
| | | WBPaper00066110:tetraploid_vs_diploid_upregulated |
| | | WBPaper00066232:hsf-1(RNAi)_upregulated_WT |
| | | cgc4489_group_15 |
| | | WBPaper00025141:N2_Expressed_Genes |
| | | WBPaper00025141:unc-4::GFP_Expressed_Genes |
| | | WBPaper00035873:dpy-10_regulated |
| | | WBPaper00035873:osm-8_regulated |
| | | WBPaper00035905:FBF-1_Associated |
| | | WBPaper00036286:Pattern_B |
| | | WBPaper00038304:octr-1_regulated |
| | | WBPaper00040823:alg-1(gk214)_upregulated |
| | | WBPaper00041174:environmental |
| | | WBPaper00041174:genotypic |
| | | WBPaper00041174:genotypic_and_environmental |
| | | WBPaper00041939:control_vs_UVC-EtBr-exposed_48h |
| | | WBPaper00041939:control_vs_UVC-EtBr-exposed_51h |
| | | WBPaper00045673:colistin_downregulated |
| | | WBPaper00048989:N2_rapamycin_upregulated |
| | | [cgc5767]:expression_class_M |
| | | [cgc5767]:expression_class_SM |
| | | [cgc6390]:Cluster_D |
| | | [cgc6390]:intrinsic |
| | Interaction (64) |
| | Anatomy_function | WBbtf0506 |
| Map_info | Map | I | Position | 4.49216 | Error | 0.029361 |
| | Well_ordered |
| | Positive | Positive_clone | C03C11 | Person_evidence | WBPerson159 |
| | | | | Author_evidence | Chen P-J |
| | | | | | Singal A |
| | | | | Inferred_automatically | From sequence, transcript, pseudogene data |
| | Mapping_data | Multi_point (22) |
| | | Pos_neg_data (23) |
| Reference (105) |
| Picture | WBPicture0000013095 |
| Method | Gene |
