WormBase Tree Display for Gene: WBGene00001085
expand all nodes | collapse all nodes | view schema
WBGene00001085 | SMap | S_parent | Sequence | C25G4 | |||
---|---|---|---|---|---|---|---|
Identity (6) | |||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | dpy | ||||||
Reference_allele | WBVar00089317 | ||||||
Allele (97) | |||||||
Legacy_information | n199mat : XX daughters of n199/+ mothers are maternally rescued weak dumpy phenotype with protruding vulva (ES2) 4% Him; XX daughters of n199/n199 mothers are severely dumpy and Him (2% of brood) or die as embryos or young larvae (98% of XX brood). XO n199 animals are non-dumpy almost wildtype males (ME3). Similar or slightly stronger phenotypes in n199/Df. NA3 (n198 (resembles n199) y6 (weaker phenotypes). | ||||||
See also n198, n199, y6 | |||||||
[C.elegansII] n199mat : XX daughters of n199/+ mothers are maternally rescued weak dumpy phenotype with protruding vulva (ES2) 4% Him; XX daughters of n199/n199 mothers are severely dumpy and Him (2% of brood) or die as embryos or young larvae (98% of XX brood). XO n199 animals are non-dumpy almost wildtype males (ME3). Similar or slightly stronger phenotypes in n199/Df. OA3: n198 (resembles n199), y6 (weaker phenotypes), y65. Cloned: encodes predicted 1263 aa novel protein; antibody staining indicates DPY-26 associated with X chromosomes in XX, diffuse nuclear in XO. [Plenefisch et al. 1989; TY] | |||||||
Strain | WBStrain00004455 | ||||||
WBStrain00004613 | |||||||
WBStrain00004619 | |||||||
WBStrain00004623 | |||||||
WBStrain00034748 | |||||||
WBStrain00054695 | |||||||
RNASeq_FPKM (74) | |||||||
GO_annotation (15) | |||||||
Contained_in_operon | CEOP4516 | ||||||
Ortholog (18) | |||||||
Structured_description | Concise_description | dpy-26 encodes a novel, acidic protein that is highly conserved in other Caenorhabditis species; during development, dpy-26 activity is required for both dosage compensation and meiotic chromosome segregation; DPY-26 localizes to all meiotic chromosomes in the germline and to the hermaphrodite X chromosomes in somatic cells; SDC-1, SDC-2, and SDC-3 proteins form a complex and these three proteins, in turn, colocalize with DPY-26, DPY-27, and MIX-1 proteins both on the X chromosome and on a transgenic her-1(+) array. | Paper_evidence | WBPaper00002605 | |||
WBPaper00002606 | |||||||
WBPaper00005215 | |||||||
Curator_confirmed | WBPerson1843 | ||||||
WBPerson567 | |||||||
Date_last_updated | 21 May 2007 00:00:00 | ||||||
Automated_description | Involved in dosage compensation by hypoactivation of X chromosome; meiotic sister chromatid segregation; and mitotic sister chromatid segregation. Located in condensed nuclear chromosome. Part of dosage compensation complex. Expressed widely. | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Molecular_info | Corresponding_CDS | C25G4.5 | |||||
Corresponding_transcript | C25G4.5.1 | ||||||
Other_sequence | U43562 | ||||||
CBC04037_1 | |||||||
CR05839 | |||||||
CRC11903_1 | |||||||
PPC12755_1 | |||||||
CBC13777_1 | |||||||
CBC01161_1 | |||||||
CRC07128_1 | |||||||
Associated_feature | WBsf652298 | ||||||
WBsf668431 | |||||||
WBsf231021 | |||||||
WBsf231022 | |||||||
WBsf231023 | |||||||
Experimental_info | RNAi_result | WBRNAi00041214 | Inferred_automatically | RNAi_primary | |||
WBRNAi00011181 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00080293 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00080269 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00080286 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00080273 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00080282 | Inferred_automatically | RNAi_primary | |||||
Expr_pattern | Expr1570 | ||||||
Expr9851 | |||||||
Expr1022687 | |||||||
Expr1030690 | |||||||
Expr1145250 | |||||||
Expr1200198 | |||||||
Expr2011067 | |||||||
Expr2029304 | |||||||
Drives_construct | WBCnstr00037090 | ||||||
Construct_product | WBCnstr00037090 | ||||||
Antibody | WBAntibody00000131 | ||||||
WBAntibody00000807 | |||||||
WBAntibody00000808 | |||||||
WBAntibody00001591 | |||||||
WBAntibody00001964 | |||||||
WBAntibody00002034 | |||||||
WBAntibody00002040 | |||||||
WBAntibody00002734 | |||||||
Microarray_results (23) | |||||||
Expression_cluster (104) | |||||||
Interaction (86) | |||||||
WBProcess | WBbiopr:00000056 | ||||||
WBbiopr:00000099 | |||||||
Map_info | Map | IV | Position | 5.94177 | Error | 0.00601 | |
Well_ordered | |||||||
Positive | Positive_clone | C25G4 | Inferred_automatically | From sequence, transcript, pseudogene data | |||
Mapping_data | 2_point | 648 | |||||
819 | |||||||
823 | |||||||
824 | |||||||
Multi_point | 568 | ||||||
569 | |||||||
570 | |||||||
764 | |||||||
765 | |||||||
766 | |||||||
767 | |||||||
1916 | |||||||
5281 | |||||||
Landmark_gene | |||||||
Reference (112) | |||||||
Method | Gene |