WormBase Tree Display for Gene: WBGene00000929
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| WBGene00000929 | SMap | S_parent | Sequence | K07E3 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | dao-3 | Person_evidence | WBPerson359 | |||||
| Sequence_name | K07E3.3 | ||||||||
| Molecular_name | K07E3.3 | ||||||||
| K07E3.3.1 | |||||||||
| CE25047 | |||||||||
| Other_name | CELE_K07E3.3 | Accession_evidence | NDB | BX284606 | |||||
| Public_name | dao-3 | ||||||||
| DB_info | Database | AceView | gene | XI704 | |||||
| WormQTL | gene | WBGene00000929 | |||||||
| WormFlux | gene | WBGene00000929 | |||||||
| NDB | locus_tag | CELE_K07E3.3 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00000929|UniProtKB=Q21285 | |||||||
| family | PTHR48099 | ||||||||
| NCBI | gene | 181065 | |||||||
| RefSeq | protein | NM_076961.7 | |||||||
| TREEFAM | TREEFAM_ID | TF323998 | |||||||
| TrEMBL | UniProtAcc | Q21285 | |||||||
| UniProt_GCRP | UniProtAcc | Q21285 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:22 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | dao | ||||||||
| Allele (46) | |||||||||
| Strain | WBStrain00001880 | ||||||||
| WBStrain00036407 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (11) | |||||||||
| Ortholog (53) | |||||||||
| Paralog | WBGene00019492 | Caenorhabditis elegans | From_analysis | WormBase-Compara | |||||
| Structured_description | Concise_description | dao-3 encodes a protein containing tetrahydrofolate dehydrogenase/cyclohydrolase catalytic and NAD(P)-binding domains; by similarity to mammalian enzymes, DAO-3 is predicted to function in one-carbon unit metabolism and thus, in amino acid and nucleotide biosynthesis; dao-3 expression appears to be regulated by daf-2-mediated insulin signaling: microarray experiments suggest that it is upregulated in daf-2 mutant adults, while differential display and Northern analyses suggest that it is down-regulated; a dao-3 promoter gfp fusion is expressed in larvae in the hypodermis and in the nervous system, including tail neurons and phasmids. | Paper_evidence | WBPaper00005073 | |||||
| WBPaper00005976 | |||||||||
| WBPaper00006525 | |||||||||
| WBPaper00024278 | |||||||||
| Curator_confirmed | WBPerson48 | ||||||||
| WBPerson1843 | |||||||||
| Date_last_updated | 24 May 2006 00:00:00 | ||||||||
| Automated_description | Predicted to enable methenyltetrahydrofolate cyclohydrolase activity and methylenetetrahydrofolate dehydrogenase (NADP+) activity. Predicted to be involved in tetrahydrofolate interconversion. Predicted to be located in cytosol. Is an ortholog of human MTHFD2 (methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | K07E3.3 | |||||||
| Corresponding_transcript | K07E3.3.1 | ||||||||
| Other_sequence (50) | |||||||||
| Associated_feature | WBsf655682 | ||||||||
| WBsf670806 | |||||||||
| WBsf670807 | |||||||||
| WBsf1006047 | |||||||||
| WBsf1006048 | |||||||||
| WBsf1023360 | |||||||||
| WBsf237644 | |||||||||
| WBsf237645 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00063194 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00034076 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00067389 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00063195 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00050168 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00016731 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr6350 | ||||||||
| Expr1022129 | |||||||||
| Expr1030579 | |||||||||
| Expr1153863 | |||||||||
| Expr2010787 | |||||||||
| Expr2029024 | |||||||||
| Drives_construct | WBCnstr00002673 | ||||||||
| WBCnstr00037195 | |||||||||
| Construct_product | WBCnstr00037195 | ||||||||
| Microarray_results (18) | |||||||||
| Expression_cluster (213) | |||||||||
| Interaction (47) | |||||||||
| Map_info | Map | X | Position | -0.59367 | Error | 0.006467 | |||
| Positive | Positive_clone | K07E3 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Pseudo_map_position | |||||||||
| Reference (11) | |||||||||
| Remark | Sequence connection from [Yu H, Larsen PL], [krb 020711] | ||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
