WormBase Tree Display for Gene: WBGene00000929
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| WBGene00000929 | SMap | S_parent | Sequence | K07E3 | |||
|---|---|---|---|---|---|---|---|
| Identity (6) | |||||||
| Gene_info | Biotype | SO:0001217 | |||||
| Gene_class | dao | ||||||
| Allele (46) | |||||||
| Strain | WBStrain00001880 | ||||||
| WBStrain00036407 | |||||||
| RNASeq_FPKM (74) | |||||||
| GO_annotation (11) | |||||||
| Ortholog (53) | |||||||
| Paralog | WBGene00019492 | Caenorhabditis elegans | From_analysis | WormBase-Compara | |||
| Structured_description | Concise_description | dao-3 encodes a protein containing tetrahydrofolate dehydrogenase/cyclohydrolase catalytic and NAD(P)-binding domains; by similarity to mammalian enzymes, DAO-3 is predicted to function in one-carbon unit metabolism and thus, in amino acid and nucleotide biosynthesis; dao-3 expression appears to be regulated by daf-2-mediated insulin signaling: microarray experiments suggest that it is upregulated in daf-2 mutant adults, while differential display and Northern analyses suggest that it is down-regulated; a dao-3 promoter gfp fusion is expressed in larvae in the hypodermis and in the nervous system, including tail neurons and phasmids. | Paper_evidence | WBPaper00005073 | |||
| WBPaper00005976 | |||||||
| WBPaper00006525 | |||||||
| WBPaper00024278 | |||||||
| Curator_confirmed | WBPerson48 | ||||||
| WBPerson1843 | |||||||
| Date_last_updated | 24 May 2006 00:00:00 | ||||||
| Automated_description | Predicted to enable methenyltetrahydrofolate cyclohydrolase activity and methylenetetrahydrofolate dehydrogenase (NADP+) activity. Predicted to be involved in tetrahydrofolate interconversion. Predicted to be located in cytosol. Is an ortholog of human MTHFD2 (methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase). | Paper_evidence | WBPaper00065943 | ||||
| Curator_confirmed | WBPerson324 | ||||||
| WBPerson37462 | |||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
| Molecular_info | Corresponding_CDS | K07E3.3 | |||||
| Corresponding_transcript | K07E3.3.1 | ||||||
| Other_sequence (50) | |||||||
| Associated_feature | WBsf655682 | ||||||
| WBsf670806 | |||||||
| WBsf670807 | |||||||
| WBsf1006047 | |||||||
| WBsf1006048 | |||||||
| WBsf1023360 | |||||||
| WBsf237644 | |||||||
| WBsf237645 | |||||||
| Experimental_info | RNAi_result | WBRNAi00063194 | Inferred_automatically | RNAi_primary | |||
| WBRNAi00034076 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00067389 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00063195 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00050168 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00016731 | Inferred_automatically | RNAi_primary | |||||
| Expr_pattern | Expr6350 | ||||||
| Expr1022129 | |||||||
| Expr1030579 | |||||||
| Expr1153863 | |||||||
| Expr2010787 | |||||||
| Expr2029024 | |||||||
| Drives_construct | WBCnstr00002673 | ||||||
| WBCnstr00037195 | |||||||
| Construct_product | WBCnstr00037195 | ||||||
| Microarray_results (18) | |||||||
| Expression_cluster (213) | |||||||
| Interaction (47) | |||||||
| Map_info | Map | X | Position | -0.59367 | Error | 0.006467 | |
| Positive | Positive_clone | K07E3 | Inferred_automatically | From CDS info | |||
| From sequence, transcript, pseudogene data | |||||||
| Pseudo_map_position | |||||||
| Reference (11) | |||||||
| Remark | Sequence connection from [Yu H, Larsen PL], [krb 020711] | ||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||
| Method | Gene |
