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WormBase Tree Display for Gene: WBGene00019492

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Name Class

WBGene00019492SMapS_parentSequenceK07E3
IdentityVersion1
NameSequence_nameK07E3.4
Molecular_nameK07E3.4a
K07E3.4a.1
CE18020
K07E3.4b
K07E3.4b.1
Other_nameCELE_K07E3.4Accession_evidenceNDBBX284606
Public_nameK07E3.4
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change128 May 2004 13:31:01WBPerson1971EventImportedInitial conversion from CDS class of stlace from WS125
StatusLive
Gene_infoBiotypeSO:0001217
Allele (59)
StrainWBStrain00002274
RNASeq_FPKM (74)
GO_annotation00071098
00071099
00071100
00071101
00124330
00124331
Ortholog (55)
ParalogWBGene00000929Caenorhabditis elegansFrom_analysisWormBase-Compara
Structured_descriptionAutomated_descriptionPredicted to enable ATP binding activity and formate-tetrahydrofolate ligase activity. Predicted to be involved in tetrahydrofolate interconversion. Human ortholog(s) of this gene implicated in several diseases, including Down syndrome; cleft lip; and developmental cardiac valvular defect. Is an ortholog of human MTHFD1 (methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0080633Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:7432)
DOID:7693Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:7432)
DOID:14250Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:7432)
DOID:0080074Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:21055,HGNC:7432)
DOID:9296Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:7432)
DOID:6419Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:7432)
DOID:0080016Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:7432)
DOID:674Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:7432)
Molecular_infoCorresponding_CDSK07E3.4a
K07E3.4b
Corresponding_CDS_historyK07E3.4:wp19
Corresponding_transcriptK07E3.4a.1
K07E3.4b.1
Other_sequence (110)
Associated_featureWBsf654186
WBsf654187
WBsf670803
WBsf670804
WBsf670805
WBsf237641
WBsf237642
WBsf237643
Experimental_infoRNAi_resultWBRNAi00016732Inferred_automaticallyRNAi_primary
WBRNAi00050169Inferred_automaticallyRNAi_primary
Expr_patternChronogram454
Expr6351
Expr1025644
Expr1038424
Expr1153864
Expr2004863
Expr2023084
Drives_constructWBCnstr00002974
WBCnstr00025799
Construct_productWBCnstr00025799
Microarray_results (20)
Expression_cluster (195)
Interaction (127)
Map_infoPositivePositive_cloneK07E3Inferred_automaticallyFrom sequence, transcript, pseudogene data
Interpolated_map_positionX-0.598083
ReferenceWBPaper00032322
WBPaper00038491
WBPaper00055090
WBPaper00065331
MethodGene