WormBase Tree Display for Gene: WBGene00019492

WBGene00019492 SMap: S_parent: Sequence: K07E3
  Identity: Version: 1
    Name: Sequence_name: K07E3.4
      Molecular_name: K07E3.4a
        K07E3.4a.1
        CE18020
        K07E3.4b
        K07E3.4b.1
      Other_name: CELE_K07E3.4 Accession_evidence: NDB BX284606
      Public_name: K07E3.4
    DB_info: Database (11)
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:31:01 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
    Status: Live
  Gene_info: Biotype: SO:0001217
    Allele (59)
    Strain: WBStrain00002274
    RNASeq_FPKM (74)
    GO_annotation: 00071098
      00071099
      00071100
      00071101
      00124330
      00124331
    Ortholog (55)
    Paralog: WBGene00000929 Caenorhabditis elegans From_analysis: WormBase-Compara
    Structured_description: Automated_description: Predicted to enable ATP binding activity and formate-tetrahydrofolate ligase activity. Predicted to be involved in tetrahydrofolate interconversion. Human ortholog(s) of this gene implicated in several diseases, including Down syndrome; cleft lip; and developmental cardiac valvular defect. Is an ortholog of human MTHFD1 (methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:0080633 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:7432)
      DOID:7693 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:7432)
      DOID:14250 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:7432)
      DOID:0080074 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:21055,HGNC:7432)
      DOID:9296 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:7432)
      DOID:6419 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:7432)
      DOID:0080016 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:7432)
      DOID:674 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:7432)
  Molecular_info: Corresponding_CDS: K07E3.4a
      K07E3.4b
    Corresponding_CDS_history: K07E3.4:wp19
    Corresponding_transcript: K07E3.4a.1
      K07E3.4b.1
    Other_sequence: AAC00164_1
      MJ04749
      Oden_isotig14072
      XI04706
      MCC02807_1
      EY461640.1
      Oden_isotig03474
      MI03729
      ACC00855_1
      HGC09517_1
      FG979875.1
      FC549860.1
      FC555021.1
      ACC11729_1
      Tcol_isotig10078
      ACC18459_1
      GP02331
      MI03518
      ACC07615_1
      EX538723.1
      Name_isotig03029
      FK809780.1
      CR04827
      EY459916.1
      SSC02906_1
      CRC04780_1
      XIC05309_1
      ACC09894_1
      EY462228.1
      SSC05771_1
      FF679300.1
      NAC01568_1
      EX557860.1
      CJC13139_1
      EY458356.1
      Oden_isotig03473
      BU087047.1
      EX559441.1
      Acan_isotig14429
      FC539115.1
      EX560726.1
      Oden_isotig03477
      MJC03893_1
      Oden_isotig14073
      EX541970.1
      CRC01877_1
      GRC00538_1
      Dviv_isotig24236
      FF678339.1
      MI01062
      MIC00045_1
      FK801737.1
      EY471785.1
      EX562320.1
      FF680386.1
      GO250331.1
      Oden_isotig27870
      ACC15448_1
      BXC06535_1
      GR14328
      HG01617
      EY468395.1
      Tcir_isotig13760
      HBC21820_1
      Hbac_isotig01317
      EY464553.1
      FK804467.1
      Tcir_isotig17434
      FG977328.1
      MI04159
      EY467094.1
      MC03027
      HCC12357_1
      Oden_isotig03478
      FF679367.1
      FK808861.1
      FC543198.1
      Oden_isotig03475
      EX554218.1
      MCC00719_1
      FC553365.1
      Acan_isotig17017
      CJC03118_1
      MC01794
      HC09660
      Oden_isotig03476
      BXC06190_1
      Oden_isotig03480
      Oden_isotig29413
      HBC03706_1
      GPC02781_1
      ACC03665_1
      EY472421.1
      FF679658.1
      BXC05318_1
      EX566316.1
      Dviv_isotig25820
      CBC11658_1
      Tcol_isotig10079
      ES411489.1
      Acan_isotig18681
      ACC29272_1
      DN190930.1
      SS00751
      Oden_isotig03479
      Acan_isotig02847
      Acan_isotig02848
      Acan_isotig07640
      BUC00289_1
      ACC00855_2
    Associated_feature: WBsf654186
      WBsf654187
      WBsf670803
      WBsf670804
      WBsf670805
      WBsf237641
      WBsf237642
      WBsf237643
  Experimental_info: RNAi_result: WBRNAi00016732 Inferred_automatically: RNAi_primary
      WBRNAi00050169 Inferred_automatically: RNAi_primary
    Expr_pattern: Chronogram454
      Expr6351
      Expr1025644
      Expr1038424
      Expr1153864
      Expr2004863
      Expr2023084
    Drives_construct: WBCnstr00002974
      WBCnstr00025799
    Construct_product: WBCnstr00025799
    Microarray_results (20)
    Expression_cluster (195)
    Interaction (127)
  Map_info: Positive: Positive_clone: K07E3 Inferred_automatically: From sequence, transcript, pseudogene data
    Interpolated_map_position: X -0.598083
  Reference: WBPaper00032322
    WBPaper00038491
    WBPaper00055090
    WBPaper00065331
  Method: Gene