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WormBase Tree Display for Gene: WBGene00000830

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Name Class

WBGene00000830SMapS_parentSequenceY54G11A
IdentityVersion1
NameCGC_namectl-1Person_evidenceWBPerson95
Sequence_nameY54G11A.6
Molecular_nameY54G11A.6
Y54G11A.6.1
CE30713
Other_namecat2Accession_evidenceEMBLY14065
Y14066
CELE_Y54G11A.6Accession_evidenceNDBBX284602
Public_namectl-1
DB_infoDatabase (13)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:21WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classctl
AlleleWBVar00092490Inferred_automaticallyFrom strain object: RB1197
WBVar00266706
WBVar02120966
WBVar01499702
WBVar02123374
WBVar02157773
WBVar00788090
WBVar01498435
WBVar02123755
WBVar02120821
WBVar02122113
WBVar02120470
WBVar02120661
WBVar02121399
WBVar02151124
WBVar01498690
WBVar00299667
WBVar02124400
WBVar02123670
WBVar00265496
WBVar02122226
WBVar01499490
WBVar01498941
WBVar01498758
WBVar02123895
WBVar02122796
StrainWBStrain00031898
RNASeq_FPKM (74)
GO_annotation (20)
Ortholog (42)
ParalogWBGene00000831Caenorhabditis elegansFrom_analysisInparanoid_8
Panther
WormBase-Compara
WBGene00013220Caenorhabditis elegansFrom_analysisTreeFam
Inparanoid_8
Panther
WormBase-Compara
Structured_descriptionConcise_descriptionctl-1 encodes one of three C. elegans catalases; CTL-1 exhibits catalase activity in vitro, and thus likely functions in vivo as an antioxidant enzyme that protects cells from reactive oxygen species; ctl-1 activity contributes to the extended lifespan seen in daf-2 mutant animals; in addition, ctl-1 expression is negatively regulated by DAF-2-mediated insulin signaling; as CTL-1 does not possess a C-terminal peroxisomal targeting signal (PTS), it is predicted to be a cytosolic catalase.Paper_evidenceWBPaper00003973
WBPaper00005976
WBPaper00006515
Curator_confirmedWBPerson48
WBPerson1843
Date_last_updated23 May 2006 00:00:00
Automated_descriptionEnables catalase activity. Predicted to be involved in hydrogen peroxide catabolic process and response to hydrogen peroxide. Predicted to be located in mitochondrion and peroxisome. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); eye disease (multiple); and lung disease (multiple). Is an ortholog of human CAT (catalase).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_model (48)
Molecular_infoCorresponding_CDSY54G11A.6
Corresponding_CDS_historyY54G11A.6:wp78
Corresponding_transcriptY54G11A.6.1
Other_sequenceU55384
Y14066
FK804873.1
Oden_isotig01936
CR11442
Oden_isotig01948
Oden_isotig01942
Oden_isotig01946
Dviv_isotig04966
FK801397.1
Oden_isotig01939
BXC01536_1
TDC00477_1
BUC00074_1
Oden_isotig01938
Oden_isotig01951
FK804152.1
Name_isotig01007
Oden_isotig01950
EX013089.1
Oden_isotig01949
ES413011.1
FF679828.1
Oden_isotig01955
FK804330.1
Oden_isotig01945
Dviv_isotig04965
BI772923.1
Oden_isotig01952
Oden_isotig01954
Oden_isotig01944
CB036691.1
Tcol_isotig14810
HC05811
MC02652
FK807640.1
Oden_isotig01937
Oden_isotig01940
CR11443
Acan_isotig03518
Oden_isotig01953
AS05134
CRC05123_1
Tcir_isotig08945
Oden_isotig01943
EE724180.1
Tcir_isotig13370
HBC01570_2
JI170349.1
Oden_isotig01947
Dviv_isotig04967
MCC01327_1
Oden_isotig01941
SSC06189_1
FG975661.1
FF680075.1
Dviv_contig33823
CB039144.1
Hbac_isotig01139
Acan_isotig19494
Associated_featureWBsf019139
WBsf019140
WBsf019141
WBsf224261
Experimental_infoRNAi_resultWBRNAi00063177Inferred_automaticallyRNAi_primary
WBRNAi00078268Inferred_automaticallyRNAi_primary
WBRNAi00103092Inferred_automaticallyRNAi_primary
WBRNAi00030271Inferred_automaticallyRNAi_primary
WBRNAi00112317Inferred_automaticallyRNAi_primary
WBRNAi00063176Inferred_automaticallyRNAi_primary
WBRNAi00063178Inferred_automaticallyRNAi_primary
WBRNAi00020988Inferred_automaticallyRNAi_primary
WBRNAi00057425Inferred_automaticallyRNAi_primary
Expr_patternExpr1318
Expr1320
Expr1030512
Expr1160867
Expr2010575
Expr2028815
Drives_constructWBCnstr00005460
WBCnstr00037260
Construct_productWBCnstr00005460
WBCnstr00010215
WBCnstr00037260
Microarray_results (25)
Expression_cluster (185)
Interaction (161)
WBProcessWBbiopr:00000039
WBbiopr:00000096
WBbiopr:00000121
Map_infoMapIIPosition22.9037Error0.000659
PositivePositive_cloneY54G11AInferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Mapping_dataMulti_point4241
4938
Pseudo_map_position
Reference (82)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene