WormBase Tree Display for Gene: WBGene00000765
expand all nodes | collapse all nodes | view schema
| WBGene00000765 | Evidence | Paper_evidence | WBPaper00013270 | ||||||
|---|---|---|---|---|---|---|---|---|---|
| SMap | S_parent | Sequence | ZK652 | ||||||
| Identity | Version | 1 | |||||||
| Name | CGC_name | coq-5 | Person_evidence | WBPerson247 | |||||
| Sequence_name | ZK652.9 | ||||||||
| Molecular_name | ZK652.9 | ||||||||
| ZK652.9.1 | |||||||||
| CE29014 | |||||||||
| Other_name | CELE_ZK652.9 | Accession_evidence | NDB | BX284603 | |||||
| Public_name | coq-5 | ||||||||
| DB_info | Database (13) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:21 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | coq | ||||||||
| Allele (15) | |||||||||
| Strain | WBStrain00036176 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (18) | |||||||||
| Contained_in_operon | CEOP3456 | ||||||||
| Ortholog (35) | |||||||||
| Paralog | WBGene00008743 | Caenorhabditis elegans | From_analysis | WormBase-Compara | |||||
| WBGene00015450 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00018811 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00019198 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00019675 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00019961 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00019963 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00019968 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00022781 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| Structured_description | Concise_description | coq-5 encodes a putative 2-hexaprenyl-6-methoxy-1,4-benzoquinonemethyltransferase, homologous to COQ5 in S. cerevisiae and to a family ofmethyltransferases involved in ubiquinone, menaquinone, biotin and sterolbiosynthesis and in phosphatidylethanolamine methylation; COQ-5 isrequired for ubiquinone (coenzyme Q9) biosynthesis and for normally shortlifespan; coq-5 can transgenically rescue a coq-5 deletion in S.cerevisiae; coq-5(RNAi) animals have reduced levels of coenzyme Q9 andsuperoxide, and have abnormally long lifespans. | Paper_evidence | WBPaper00005863 | |||||
| WBPaper00006360 | |||||||||
| WBPaper00013580 | |||||||||
| WBPaper00028295 | |||||||||
| WBPaper00028318 | |||||||||
| WBPaper00028322 | |||||||||
| WBPaper00028323 | |||||||||
| Curator_confirmed | WBPerson567 | ||||||||
| Date_last_updated | 11 Aug 2006 00:00:00 | ||||||||
| Automated_description | Predicted to enable methyltransferase activity. Involved in ubiquinone biosynthetic process. Predicted to be located in mitochondrial inner membrane. Predicted to be extrinsic component of mitochondrial inner membrane. Human ortholog(s) of this gene implicated in primary coenzyme Q10 deficiency 9. Is an ortholog of human COQ5 (coenzyme Q5, methyltransferase). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0112138 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:28722) | ||||
| Molecular_info | Corresponding_CDS | ZK652.9 | |||||||
| Corresponding_transcript | ZK652.9.1 | ||||||||
| Other_sequence (68) | |||||||||
| Associated_feature | WBsf651225 | ||||||||
| WBsf227038 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00005431 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00059622 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00022974 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00059609 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr1015393 | ||||||||
| Expr1030470 | |||||||||
| Expr1163027 | |||||||||
| Expr2010465 | |||||||||
| Expr2028705 | |||||||||
| Drives_construct | WBCnstr00037294 | ||||||||
| Construct_product | WBCnstr00037294 | ||||||||
| Microarray_results (15) | |||||||||
| Expression_cluster (80) | |||||||||
| Interaction (87) | |||||||||
| Map_info | Map | III | Position | -0.544031 | Error | 0.000977 | |||
| Positive | Positive_clone | ZK652 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00005863 | ||||||||
| WBPaper00006360 | |||||||||
| WBPaper00011299 | |||||||||
| WBPaper00019114 | |||||||||
| WBPaper00027431 | |||||||||
| WBPaper00038491 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00061547 | |||||||||
| WBPaper00062388 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
