WormBase Tree Display for Gene: WBGene00000532

WBGene00000532 SMap: S_parent: Sequence: CHROMOSOME_II
  Identity: Version: 1
    Name: CGC_name: clh-5
      Sequence_name: C07H4.2
      Molecular_name: C07H4.2
        C07H4.2.1
        CE27360
      Other_name: CELE_C07H4.2 Accession_evidence: NDB BX284602
      Public_name: clh-5
    DB_info: Database (11)
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:21 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: clh
    Allele (64)
    Strain: WBStrain00001511
    RNASeq_FPKM (74)
    GO_annotation (16)
    Ortholog: WBGene00053231 Caenorhabditis remanei From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00026154 Caenorhabditis briggsae From_analysis: Hillier-set
            OrthoMCL
            OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00150216 Caenorhabditis brenneri From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00124111 Caenorhabditis japonica From_analysis: TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00193612 Caenorhabditis brenneri From_analysis: TreeFam
            WormBase-Compara
      WBGene00222315 Brugia malayi From_analysis: WormBase-Compara
      CBOVI.g7523 Caenorhabditis bovis From_analysis: WormBase-Compara
      CSP21.g3107 Caenorhabditis parvicauda From_analysis: WormBase-Compara
      CSP26.g16024 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP28.g17144 Caenorhabditis panamensis From_analysis: WormBase-Compara
      CSP29.g20159 Caenorhabditis becei From_analysis: WormBase-Compara
      CSP31.g17310 Caenorhabditis uteleia From_analysis: WormBase-Compara
      CSP32.g7681 Caenorhabditis sulstoni From_analysis: WormBase-Compara
      CSP38.g8525 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      CSP39.g5166 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP40.g982 Caenorhabditis tribulationis From_analysis: WormBase-Compara
      Cang_2012_03_13_00047.g2494 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cni-clh-5 Caenorhabditis nigoni From_analysis: WormBase-Compara
      Csp11.Scaffold629.g7517 Caenorhabditis tropicalis From_analysis: WormBase-Compara
      Csp5_scaffold_00023.g1359 Caenorhabditis sinica From_analysis: WormBase-Compara
      FL83_20683 Caenorhabditis latens From_analysis: WormBase-Compara
      GCK72_005663 Caenorhabditis remanei From_analysis: WormBase-Compara
      OTIPU.nOt.2.0.1.g11947 Oscheius tipulae From_analysis: WormBase-Compara
      Pan_g3759 Panagrellus redivivus From_analysis: WormBase-Compara
      Sp34_20303100 Caenorhabditis inopinata From_analysis: WormBase-Compara
      chrII_pilon.g5406 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00246914 Onchocerca volvulus From_analysis: WormBase-Compara
      WBGene00274922 Pristionchus pacificus From_analysis: WormBase-Compara
      WBGene00268083 Strongyloides ratti From_analysis: WormBase-Compara
      WBGene00289725 Trichuris muris From_analysis: WormBase-Compara
      SGD:S000003801 Saccharomyces cerevisiae From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      FB:FBgn0036566 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      ZFIN:ZDB-GENE-110407-11 Danio rerio From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      ZFIN:ZDB-GENE-030131-1699 Danio rerio From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      ZFIN:ZDB-GENE-091113-15 Danio rerio From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      ZFIN:ZDB-GENE-061013-353 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      HGNC:2021 Homo sapiens From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      HGNC:2022 Homo sapiens From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      HGNC:2023 Homo sapiens From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      MGI:103555 Mus musculus From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      MGI:104571 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      MGI:99486 Mus musculus From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      RGD:2362 Rattus norvegicus From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      RGD:708381 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      RGD:621219 Rattus norvegicus From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
    Paralog: WBGene00000533 Caenorhabditis elegans From_analysis: TreeFam
            WormBase-Compara
      WBGene00000528 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00000529 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00000530 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00000531 Caenorhabditis elegans From_analysis: WormBase-Compara
    Structured_description: Concise_description: The clh-5 gene encodes a chloride channel, whose human homologs include CLC1 and CLCN5; the latter homolog is imvolved in receptor-mediated endocytosis. Paper_evidence: WBPaper00004103
            WBPaper00004883
            WBPaper00012835
          Curator_confirmed: WBPerson567
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Predicted to enable voltage-gated chloride channel activity. Predicted to be involved in chloride transmembrane transport. Predicted to be located in Golgi apparatus; early endosome; and synaptic vesicle. Expressed in several structures, including head and tail. Human ortholog(s) of this gene implicated in Raynaud-Claes syndrome and X-linked recessive disease (multiple). Is an ortholog of human CLCN4 (chloride voltage-gated channel 4). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:0111815 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2023)
      DOID:0050699 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2023)
      DOID:0112060 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2022)
      DOID:0111798 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2023)
      DOID:0080353 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2023)
  Molecular_info: Corresponding_CDS: C07H4.2
    Corresponding_CDS_history: C07H4.2:wp48
    Corresponding_transcript: C07H4.2.1
    Other_sequence (49)
    Associated_feature: WBsf223603
  Experimental_info: RNAi_result: WBRNAi00062113 Inferred_automatically: RNAi_primary
      WBRNAi00086835 Inferred_automatically: RNAi_primary
      WBRNAi00065615 Inferred_automatically: RNAi_primary
      WBRNAi00040037 Inferred_automatically: RNAi_primary
      WBRNAi00028650 Inferred_automatically: RNAi_primary
      WBRNAi00077549 Inferred_automatically: RNAi_primary
      WBRNAi00010411 Inferred_automatically: RNAi_primary
    Expr_pattern: Chronogram1083
      Expr1126
      Expr5200
      Expr1027246
      Expr1030318
      Expr1144107
      Expr2010232
      Expr2028474
    Drives_construct: WBCnstr00002368
      WBCnstr00010094
      WBCnstr00037468
    Construct_product: WBCnstr00037468
    Microarray_results (21)
    Expression_cluster (103)
    Interaction (31)
  Map_info: Map: II Position: 1.01436 Error: 0.007131
    Positive: Positive_clone: C07H4 Inferred_automatically: From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 4337
        5255
        5491
    Pseudo_map_position
  Reference (17)
  Remark: sequence connection from [George AL]
    Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene