WormBase Tree Display for Gene: WBGene00000526

WBGene00000526 Evidence: Person_evidence: WBPerson765
  SMap: S_parent: Sequence: C01C10
  Identity: Version: 1
    Name: CGC_name: clc-5
      Sequence_name: C01C10.4
      Molecular_name: C01C10.4
        C01C10.4.1
        CE28882
      Other_name: CELE_C01C10.4 Accession_evidence: NDB BX284606
      Public_name: clc-5
    DB_info: Database: AceView gene XI53
        WormQTL gene WBGene00000526
        WormFlux gene WBGene00000526
        NDB locus_tag CELE_C01C10.4
        Panther gene CAEEL|WormBase=WBGene00000526|UniProtKB=Q9NGJ7
          family PTHR10671
        NCBI gene 181000
        RefSeq protein NM_076857.7
        SwissProt UniProtAcc Q9NGJ7
        TREEFAM TREEFAM_ID TF316179
        UniProt_GCRP UniProtAcc Q9NGJ7
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:21 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: clc
    Allele (47)
    Strain: WBStrain00051462
    RNASeq_FPKM (74)
    GO_annotation: 00096673
      00096674
      00096675
      00096676
      00096677
      00096678
      00107535
    Contained_in_operon: CEOPX088
    Ortholog (27)
    Paralog: WBGene00000522 Caenorhabditis elegans From_analysis: Panther
      WBGene00000523 Caenorhabditis elegans From_analysis: TreeFam
            Panther
      WBGene00013458
      WBGene00011014 Caenorhabditis elegans From_analysis: TreeFam
      WBGene00016067 Caenorhabditis elegans From_analysis: TreeFam
      WBGene00010742 Caenorhabditis elegans From_analysis: TreeFam
            Panther
      WBGene00016706 Caenorhabditis elegans From_analysis: Panther
      WBGene00021415 Caenorhabditis elegans From_analysis: Panther
    Structured_description: Concise_description: clc-5 encodes a claudin homolog that may be required for normal cohesion of apical junctions in epithelia; CLC-5 is worm-specific, with obvious homologs only in C. elegans; CLC-5 has no obvious function in mass RNAi assays; claudins are integral membrane proteins with four transmembrane sequences that are found in mammalian tight junctions (TJs), induce TJs when transgenically expressed in cells normally lacking them, and can mediate the specific conductance of of specific ions (e.g., magnesium or calcium) through TJs while blocking the flow of water. Paper_evidence (6)
          Curator_confirmed: WBPerson567
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Predicted to be located in plasma membrane. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: C01C10.4
    Corresponding_transcript: C01C10.4.1
    Other_sequence (17)
    Associated_feature: WBsf662967
      WBsf235934
  Experimental_info: RNAi_result: WBRNAi00009908 Inferred_automatically: RNAi_primary
      WBRNAi00039293 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1022861
      Expr1030313
      Expr1143411
      Expr2010045
      Expr2028286
    Drives_construct: WBCnstr00037473
    Construct_product: WBCnstr00037473
    Microarray_results (20)
    Expression_cluster (123)
    Interaction: WBInteraction000579893
  Map_info: Map: X Position: -1.72843
    Positive: Positive_clone: C01C10 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00039831
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene