cct-4 encodes a putative delta subunit of the eukaryotic cytosolic ('T complex') chaperonin, orthologous to human CCT4 (OMIM:605142); CCT-4 represses SKN-1-dependent transcription of gst-4; CCT-4 is expressed in pharynx, pharyngeal gland cells, intestine, renal gland cells, and neurons; CCT-4 is expressed in touch receptor neurons in a MEC-3-dependent fashion.
Predicted to enable unfolded protein binding activity. Involved in post-embryonic body morphogenesis. Predicted to be located in cytoplasm. Predicted to be part of chaperonin-containing T-complex. Expressed in body wall musculature; head; hypodermis; tail; and touch receptor neurons. Is an ortholog of human CCT4 (chaperonin containing TCP1 subunit 4).
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.