WormBase Tree Display for Gene: WBGene00000173

WBGene00000173 Evidence: Person_evidence: WBPerson548
  SMap: S_parent: Sequence: C35A5
  Identity: Version: 1
    Name: CGC_name: aqp-5 Person_evidence: WBPerson300
      Sequence_name: C35A5.1
      Molecular_name: C35A5.1
        C35A5.1.1
        CE42929
      Other_name: CELE_C35A5.1 Accession_evidence: NDB BX284605
      Public_name: aqp-5
    DB_info: Database: AceView gene 5K969
        WormQTL gene WBGene00000173
        WormFlux gene WBGene00000173
        NDB locus_tag CELE_C35A5.1
        Panther gene CAEEL|WormBase=WBGene00000173|UniProtKB=Q18469
          family PTHR45665
        NCBI gene 183221
        RefSeq protein NM_073290.5
        TrEMBL UniProtAcc Q18469
        UniProt_GCRP UniProtAcc Q18469
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:20 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: aqp
    Allele (24)
    RNASeq_FPKM (74)
    GO_annotation: 00061317
      00061318
      00061319
      00061320
      00061321
      00061322
      00106939
      00106940
      00106941
    Ortholog (29)
    Paralog: WBGene00000172 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00000174 Caenorhabditis elegans From_analysis: TreeFam
            WormBase-Compara
      WBGene00000169 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00000170 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00000171 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00000175 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00000176 Caenorhabditis elegans From_analysis: WormBase-Compara
    Structured_description: Concise_description: aqp-5 encodes a putative aquaporin with no known substrate, since AQP-5 expressed in Xenopus oocytes has no effect on water, glycerol, or urea permeability; AQP-5 also has no function in mass RNAi assays, perhaps reflecting genetic redundancy with its paralogs AQP-4 and AQP-6; AQP-5 is expressed in I1 and I2 pharyngeal interneurons, and is orthologous to human AQP8 (OMIM:603750). Paper_evidence: WBPaper00029039
            WBPaper00030907
          Curator_confirmed: WBPerson567
          Date_last_updated: 12 Aug 2007 00:00:00
      Automated_description: Predicted to enable water channel activity. Predicted to be involved in water transport. Located in cell surface. Expressed in I1L; I1R; I2L; and I2R. Is an ortholog of human AQP8 (aquaporin 8). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: C35A5.1
    Corresponding_CDS_history: C35A5.1:wp193
    Corresponding_transcript: C35A5.1.1
    Other_sequence: FG647856.1
    Associated_feature: WBsf647162
      WBsf232386
  Experimental_info: RNAi_result: WBRNAi00041945 Inferred_automatically: RNAi_primary
      WBRNAi00029560 Inferred_automatically: RNAi_primary
      WBRNAi00011639 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr4775
      Expr15317
      Expr1013541
      Expr1030098
      Expr1145952
      Expr2009382
      Expr2027618
    Drives_construct: WBCnstr00012235
      WBCnstr00037687
    Construct_product: WBCnstr00037687
    Microarray_results (18)
    Expression_cluster (59)
    Interaction: WBInteraction000120830
      WBInteraction000124074
      WBInteraction000144196
      WBInteraction000144950
      WBInteraction000146381
      WBInteraction000146525
      WBInteraction000148749
      WBInteraction000169023
      WBInteraction000171211
      WBInteraction000174606
      WBInteraction000178733
      WBInteraction000184532
      WBInteraction000184705
      WBInteraction000186684
      WBInteraction000189168
      WBInteraction000203822
      WBInteraction000235250
      WBInteraction000236885
      WBInteraction000243138
      WBInteraction000260594
      WBInteraction000262662
      WBInteraction000274156
      WBInteraction000275642
      WBInteraction000279043
      WBInteraction000280477
      WBInteraction000290260
      WBInteraction000290547
      WBInteraction000294916
      WBInteraction000299543
      WBInteraction000300336
      WBInteraction000307773
      WBInteraction000329246
      WBInteraction000332717
      WBInteraction000340703
      WBInteraction000340704
      WBInteraction000354160
      WBInteraction000363924
      WBInteraction000367274
      WBInteraction000367624
      WBInteraction000372992
      WBInteraction000380189
      WBInteraction000395611
      WBInteraction000397004
      WBInteraction000405716
      WBInteraction000409155
      WBInteraction000409421
      WBInteraction000410431
      WBInteraction000416254
      WBInteraction000429141
      WBInteraction000429771
      WBInteraction000429986
      WBInteraction000430196
      WBInteraction000438672
      WBInteraction000441151
      WBInteraction000446148
      WBInteraction000448742
      WBInteraction000449276
      WBInteraction000451538
      WBInteraction000461177
      WBInteraction000468460
  Map_info: Map: V Position: 2.57003 Error: 0.000173
    Positive: Positive_clone: C35A5 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00027012
    WBPaper00029039
    WBPaper00033469
    WBPaper00038491
    WBPaper00055090
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene