WormBase Tree Display for Gene: WBGene00000171
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| WBGene00000171 | Evidence | Person_evidence | WBPerson548 | ||||||
|---|---|---|---|---|---|---|---|---|---|
| SMap | S_parent | Sequence | Y69E1A | ||||||
| Identity | Version | 1 | |||||||
| Name | CGC_name | aqp-3 | Person_evidence | WBPerson300 | |||||
| Sequence_name | Y69E1A.7 | ||||||||
| Molecular_name | Y69E1A.7a | ||||||||
| Y69E1A.7a.1 | |||||||||
| CE22814 | |||||||||
| Y69E1A.7b | |||||||||
| CE49844 | |||||||||
| Y69E1A.7c | |||||||||
| CE51447 | |||||||||
| Y69E1A.7b.1 | |||||||||
| Y69E1A.7c.1 | |||||||||
| Other_name | CELE_Y69E1A.7 | Accession_evidence | NDB | BX284604 | |||||
| Public_name | aqp-3 | ||||||||
| DB_info | Database | AceView | gene | 4L724 | |||||
| WormQTL | gene | WBGene00000171 | |||||||
| WormFlux | gene | WBGene00000171 | |||||||
| NDB | locus_tag | CELE_Y69E1A.7 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00000171|UniProtKB=Q9XW36 | |||||||
| family | PTHR43829 | ||||||||
| NCBI | gene | 190553 | |||||||
| RefSeq | protein | NM_001306967.3 | |||||||
| NM_069643.2 | |||||||||
| NM_001322776.4 | |||||||||
| TrEMBL | UniProtAcc | A0A131MBS2 | |||||||
| A0A061ADS9 | |||||||||
| Q9XW36 | |||||||||
| UniProt_GCRP | UniProtAcc | Q9XW36 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:20 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | aqp | ||||||||
| Allele (74) | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (16) | |||||||||
| Ortholog (51) | |||||||||
| Paralog | WBGene00000169 | Caenorhabditis elegans | From_analysis | TreeFam | |||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00000170 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00000176 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00000175 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00013272 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WBGene00000172 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00000173 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00000174 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| Structured_description | Concise_description | aqp-3 encodes an aquaglyceroporin whose expression in Xenopus oocytes increases water or glycerol permeability five- to seven-fold; loss of AQP-3 activity via mutation or RNAi results in no obvious defects; however, AQP-3, in conjunction with AQP-2, AQP-4, and AQP-8, is weakly required for recovery from hypotonic stress; AQP-3 is expressed in the intestine, excretory cell, seminal vesicle, and vas deferens. | Paper_evidence | WBPaper00029039 | |||||
| WBPaper00030907 | |||||||||
| Curator_confirmed | WBPerson567 | ||||||||
| Date_last_updated | 12 Aug 2007 00:00:00 | ||||||||
| Automated_description | Enables water channel activity. Involved in glycerol transmembrane transport and water transport. Predicted to be located in basolateral plasma membrane. Expressed in excretory cell; intestine; and vas deferens. Human ortholog(s) of this gene implicated in several diseases, including brain edema; inflammatory bowel disease (multiple); and morbid obesity. Is an ortholog of several human genes including AQP3 (aquaporin 3 (Gill blood group)); AQP7 (aquaporin 7); and AQP9 (aquaporin 9). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:4724 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:636) | ||||
| DOID:8577 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:640) | ||||||
| DOID:8778 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:640) | ||||||
| DOID:9352 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:640) | ||||||
| DOID:0060180 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:640) | ||||||
| DOID:11981 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:640) | ||||||
| Molecular_info | Corresponding_CDS | Y69E1A.7a | |||||||
| Y69E1A.7b | |||||||||
| Y69E1A.7c | |||||||||
| Corresponding_transcript | Y69E1A.7a.1 | ||||||||
| Y69E1A.7b.1 | |||||||||
| Y69E1A.7c.1 | |||||||||
| Other_sequence (63) | |||||||||
| Associated_feature | WBsf997736 | ||||||||
| Experimental_info | RNAi_result | WBRNAi00101341 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00101338 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00058066 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00021326 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr4773 | ||||||||
| Expr1015507 | |||||||||
| Expr1161482 | |||||||||
| Drives_construct | WBCnstr00012233 | ||||||||
| WBCnstr00037689 | |||||||||
| Construct_product | WBCnstr00037689 | ||||||||
| Microarray_results (18) | |||||||||
| Expression_cluster (78) | |||||||||
| Interaction | WBInteraction000105397 | ||||||||
| WBInteraction000114965 | |||||||||
| WBInteraction000115206 | |||||||||
| WBInteraction000122527 | |||||||||
| WBInteraction000122529 | |||||||||
| WBInteraction000140732 | |||||||||
| WBInteraction000166768 | |||||||||
| WBInteraction000188503 | |||||||||
| WBInteraction000199769 | |||||||||
| WBInteraction000207045 | |||||||||
| WBInteraction000221334 | |||||||||
| WBInteraction000241622 | |||||||||
| WBInteraction000247265 | |||||||||
| WBInteraction000251236 | |||||||||
| WBInteraction000251517 | |||||||||
| WBInteraction000252211 | |||||||||
| WBInteraction000259574 | |||||||||
| WBInteraction000270636 | |||||||||
| WBInteraction000273277 | |||||||||
| WBInteraction000274815 | |||||||||
| WBInteraction000289624 | |||||||||
| WBInteraction000293441 | |||||||||
| WBInteraction000295612 | |||||||||
| WBInteraction000297587 | |||||||||
| WBInteraction000299726 | |||||||||
| WBInteraction000311930 | |||||||||
| WBInteraction000315337 | |||||||||
| WBInteraction000319262 | |||||||||
| WBInteraction000330283 | |||||||||
| WBInteraction000337138 | |||||||||
| WBInteraction000338615 | |||||||||
| WBInteraction000340154 | |||||||||
| WBInteraction000344775 | |||||||||
| WBInteraction000351403 | |||||||||
| WBInteraction000352834 | |||||||||
| WBInteraction000353008 | |||||||||
| WBInteraction000372912 | |||||||||
| WBInteraction000375112 | |||||||||
| WBInteraction000379798 | |||||||||
| WBInteraction000385964 | |||||||||
| WBInteraction000402954 | |||||||||
| WBInteraction000405139 | |||||||||
| WBInteraction000407352 | |||||||||
| WBInteraction000408973 | |||||||||
| WBInteraction000413781 | |||||||||
| WBInteraction000414119 | |||||||||
| WBInteraction000414159 | |||||||||
| WBInteraction000414586 | |||||||||
| WBInteraction000416195 | |||||||||
| WBInteraction000419870 | |||||||||
| WBInteraction000421749 | |||||||||
| WBInteraction000423849 | |||||||||
| WBInteraction000427963 | |||||||||
| WBInteraction000428916 | |||||||||
| WBInteraction000434123 | |||||||||
| WBInteraction000435690 | |||||||||
| WBInteraction000437268 | |||||||||
| WBInteraction000437708 | |||||||||
| WBInteraction000442418 | |||||||||
| WBInteraction000444915 | |||||||||
| WBInteraction000446836 | |||||||||
| WBInteraction000446931 | |||||||||
| WBInteraction000453359 | |||||||||
| WBInteraction000455127 | |||||||||
| WBInteraction000457650 | |||||||||
| WBInteraction000459760 | |||||||||
| WBInteraction000468459 | |||||||||
| Map_info | Map | IV | Position | 4.76429 | Error | 0.003171 | |||
| Positive | Positive_clone | Y69E1A | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 5507 | |||||||
| 5510 | |||||||||
| 4263 | |||||||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00029039 | ||||||||
| WBPaper00038491 | |||||||||
| WBPaper00055090 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
