WormBase Tree Display for Gene: RGD:2954
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RGD:2954 | Identity | Name | CGC_name | Kcnb1 | Inferred_automatically | AGR_import |
---|---|---|---|---|---|---|
Public_name | Kcnb1 | |||||
DB_info | Database | RGD | id | 2954 | ||
AGR | cURI | RGD:2954 | ||||
EnsEMBL | ENSEMBL_geneID | ENSRNOG00000046949 | ||||
UniProt | UniProt_AC | P15387 | ||||
Species | Rattus norvegicus | |||||
Status | Live | |||||
Gene_info | Biotype | SO:0001217 | ||||
Ortholog | WBGene00021948 | Caenorhabditis elegans | From_analysis | Inparanoid | ||
OrthoFinder | ||||||
OrthoInspector | ||||||
Panther | ||||||
SonicParanoid | ||||||
WBGene00001374 | Caenorhabditis elegans | From_analysis | Inparanoid | |||
OrthoFinder | ||||||
OrthoInspector | ||||||
Panther | ||||||
SonicParanoid | ||||||
WBGene00007862 | Caenorhabditis elegans | From_analysis | EnsEMBL-Compara | |||
Inparanoid | ||||||
OrthoFinder | ||||||
OrthoInspector | ||||||
Panther | ||||||
WBGene00002242 | Caenorhabditis elegans | From_analysis | Inparanoid | |||
OrthoFinder | ||||||
OrthoInspector | ||||||
Panther | ||||||
SonicParanoid | ||||||
WBGene00012967 | Caenorhabditis elegans | From_analysis | Inparanoid | |||
OrthoFinder | ||||||
OrthoInspector | ||||||
Panther | ||||||
SonicParanoid | ||||||
Structured_description | Automated_description | Enables several functions, including protein heterodimerization activity; transmembrane transporter binding activity; and voltage-gated potassium channel activity. Involved in several processes, including clustering of voltage-gated potassium channels; positive regulation of secretion by cell; and potassium ion export across plasma membrane. Acts upstream of or within potassium ion transport. Located in several cellular components, including dendrite; lateral plasma membrane; and neuronal cell body membrane. Part of voltage-gated potassium channel complex. Is active in cholinergic synapse and postsynaptic specialization membrane. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 26 and epilepsy. Orthologous to human KCNB1 (potassium voltage-gated channel subfamily B member 1); PARTICIPATES IN insulin secretion pathway; INTERACTS WITH (5Z,8Z,11Z,13E)-15-HETE; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil. | Inferred_automatically | AGR_import |