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WormBase Tree Display for Gene: RGD:2954

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Name Class

RGD:2954IdentityNameCGC_nameKcnb1Inferred_automaticallyAGR_import
Public_nameKcnb1
DB_infoDatabaseRGDid2954
AGRcURIRGD:2954
EnsEMBLENSEMBL_geneIDENSRNOG00000046949
UniProtUniProt_ACP15387
SpeciesRattus norvegicus
StatusLive
Gene_infoBiotypeSO:0001217
OrthologWBGene00021948Caenorhabditis elegansFrom_analysisInparanoid
OrthoFinder
OrthoInspector
Panther
SonicParanoid
WBGene00001374Caenorhabditis elegansFrom_analysisInparanoid
OrthoFinder
OrthoInspector
Panther
SonicParanoid
WBGene00007862Caenorhabditis elegansFrom_analysisEnsEMBL-Compara
Inparanoid
OrthoFinder
OrthoInspector
Panther
WBGene00002242Caenorhabditis elegansFrom_analysisInparanoid
OrthoFinder
OrthoInspector
Panther
SonicParanoid
WBGene00012967Caenorhabditis elegansFrom_analysisInparanoid
OrthoFinder
OrthoInspector
Panther
SonicParanoid
Structured_descriptionAutomated_descriptionEnables several functions, including protein heterodimerization activity; transmembrane transporter binding activity; and voltage-gated potassium channel activity. Involved in several processes, including clustering of voltage-gated potassium channels; positive regulation of secretion by cell; and potassium ion export across plasma membrane. Acts upstream of or within potassium ion transport. Located in several cellular components, including dendrite; lateral plasma membrane; and neuronal cell body membrane. Part of voltage-gated potassium channel complex. Is active in cholinergic synapse and postsynaptic specialization membrane. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 26 and epilepsy. Orthologous to human KCNB1 (potassium voltage-gated channel subfamily B member 1); PARTICIPATES IN insulin secretion pathway; INTERACTS WITH (5Z,8Z,11Z,13E)-15-HETE; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.Inferred_automaticallyAGR_import