WormBase Tree Display for Interaction: WBInteraction000541100
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| WBInteraction000541100 | Interaction_type | Regulatory | Change_of_expression_level | ||
|---|---|---|---|---|---|
| Interactor | Interactor_overlapping_gene | WBGene00004758 | Interactor_type | Trans_regulator | |
| WBGene00002201 | Interactor_type | Trans_regulated | |||
| WBGene00013197 | Interactor_type | Trans_regulated | |||
| WBGene00018350 | Interactor_type | Trans_regulated | |||
| WBGene00002187 | Interactor_type | Trans_regulated | |||
| Other_interactor | CryB Treatment | Interactor_type | Trans_regulator | ||
| Variation_interactor | WBVar00088241 | Interactor_type | Trans_regulator | ||
| Interaction_summary | "For this information, we turned back to our genome-wide RNAi list of hpo genes, examined all eight of the genes that are induced by PFT (2X cut-off), and asked, based on our microarray data, if their induction is dependent upon either the p38 or JNK MAPK pathways. We found four of eight (50%) induced hpo genes (namely kin-18, Y54E5A.1, F42C5.10 and kgb-1 itself) require JNK (namely kin-18, Y54E5A.1, F42C5.10 and kgb-1 itself) require JNK MAPK for their induction whereas none of the eight genes require the p38 MAPK pathway for their induction. The dependence of these four genes upon the KGB-1 and not the p38 MAPK these four genes upon the KGB-1 and not the p38 MAPK pathway for their induction was confirmed via qRT-PCR (Figure 3E)." | ||||
| Detection_method | RT_PCR | ||||
| Regulation_level | Transcriptional | ||||
| Paper | WBPaper00038231 | ||||
| Remark | Fig. 3e |
