WormBase Tree Display for Interaction: WBInteraction000502364
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| WBInteraction000502364 | Interaction_type | Regulatory | Change_of_localization | ||
|---|---|---|---|---|---|
| Interactor | Interactor_overlapping_gene | WBGene00003992 | Interactor_type | Trans_regulated | |
| Antibody | WBAntibody00000190 | ||||
| WBGene00003864 | Interactor_type | Trans_regulator | |||
| WBGene00003865 | Interactor_type | Trans_regulator | |||
| Interaction_summary | In wild-type 2-cell and 4-cell embryos, PGL-1 is present at high levels in the posterior blastomere. PGL-1 was localized inappropriately in blastomeres in oma-1; oma-2-suppressed embryos. In all of the oma-1; oma-2-suppressed embryos, PGL-1 successfully migrated to the posterior region in one-cell embryos and was specifically inherited by the P1 blastomere as was the case in wild-type embryos. However, PGL-1 frequently failed to be partitioned in the P1 blastomere, and this resulted in incorrect distribution in descendants of P2 and EMS blastomeres. Eventually, PGL-1 became distributed abnormally in dividing embryos. | ||||
| Detection_method | Antibody | ||||
| Regulation_result | Positive_regulate | Life_stage | WBls:0000008 | ||
| Anatomy_term | WBbt:0006770 | ||||
| Paper | WBPaper00027320 |
