WormBase Tree Display for Gene: WBGene00003992
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| WBGene00003992 | SMap | S_parent | Sequence | ZK381 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | pgl-1 | Person_evidence | WBPerson632 | |||||
| Sequence_name | ZK381.4 | ||||||||
| Molecular_name | ZK381.4a | ||||||||
| ZK381.4a.1 | |||||||||
| CE25689 | |||||||||
| ZK381.4b | |||||||||
| CE07628 | |||||||||
| ZK381.4a.2 | |||||||||
| ZK381.4b.1 | |||||||||
| Other_name | CELE_ZK381.4 | Accession_evidence | NDB | BX284604 | |||||
| Public_name | pgl-1 | ||||||||
| DB_info | Database (12) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:33 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | pgl | ||||||||
| Allele (59) | |||||||||
| Legacy_information | [C.elegansII] ct131 : germline P granules unstained by some(not all) monoclonal antibodies. 5% sterile, Mes if grown at 26C. Cloned: cosmid rescue (B0318). [SS] | ||||||||
| P granules are not stained by K76 or OIC1D4, two anti-P-granule monoclonal antibodies. Mutants display sterility that is temperature-sensitive and has both a maternal and a nonmaternal component. | |||||||||
| Strain (22) | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (33) | |||||||||
| Ortholog (22) | |||||||||
| Paralog (38) | |||||||||
| Structured_description | Concise_description | pgl-1 encodes a predicted RNA-binding protein that contains a number of C-terminal RGG box motifs; PGL-1 activity is required at high temperatures during midlarval to adult stages for postembryonic germline development and hence fertility, and also for proper formation of the germline-specific P granules; PGL-1 protein, supplied maternally and embryonically, is a constitutive P granule component and thus, its localization is cytoplasmic in oocytes and early embryos, while perinuclear in the germline blastomere P4 and proliferating germ cells of larvae and adults; pgl-1 mRNA is expressed exclusively in hermaphrodite and male germlines and is detectable at all stages of development, with highest levels seen in adults; PGL-1 localization to P granules requires wild-type activity of the predicted germline helicase GLH-1. | Paper_evidence | WBPaper00003186 | |||||
| WBPaper00004672 | |||||||||
| WBPaper00004940 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 26 Aug 2004 00:00:00 | ||||||||
| Automated_description | Enables RNA endonuclease activity; identical protein binding activity; and protein self-association. Involved in P granule organization and germ-line stem cell division. Located in P granule. Expressed in germ line. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | ZK381.4a | |||||||
| ZK381.4b | |||||||||
| Corresponding_CDS_history | ZK381.4:wp150 | ||||||||
| Corresponding_transcript | ZK381.4a.1 | ||||||||
| ZK381.4a.2 | |||||||||
| ZK381.4b.1 | |||||||||
| Other_sequence | CR03959 | ||||||||
| CBC03903_1 | |||||||||
| CRC01255_1 | |||||||||
| CR03489 | |||||||||
| JI171371.1 | |||||||||
| Associated_feature | WBsf977133 | ||||||||
| WBsf977134 | |||||||||
| WBsf230205 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00113912 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00021989 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00059393 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00069464 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00007860 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00027792 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00084326 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00084334 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00084341 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern (11) | |||||||||
| Drives_construct | WBCnstr00035758 | ||||||||
| Construct_product (25) | |||||||||
| Regulate_expr_cluster (19) | |||||||||
| Antibody (25) | |||||||||
| Microarray_results (24) | |||||||||
| Expression_cluster (198) | |||||||||
| Interaction (310) | |||||||||
| Map_info | Map | IV | Position | 3.25355 | Error | 0.002367 | |||
| Well_ordered | |||||||||
| Positive | Inside_rearr | nDf41 | |||||||
| Positive_clone | B0318 | ||||||||
| ZK381 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||||
| Negative | Negative_clone | C02F1 | |||||||
| C25A8 | |||||||||
| T22D1 | |||||||||
| Mapping_data | Multi_point | 3797 | |||||||
| 3798 | |||||||||
| 3799 | |||||||||
| 3800 | |||||||||
| 3801 | |||||||||
| 4450 | |||||||||
| Pos_neg_data | 10690 | ||||||||
| Reference (159) | |||||||||
| Method | Gene |
