WormBase Tree Display for Gene: WBGene00003864
expand all nodes | collapse all nodes | view schema
| WBGene00003864 | SMap | S_parent | Sequence | CHROMOSOME_IV | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | oma-1 | Person_evidence | WBPerson374 | |||||
| Sequence_name | C09G9.6 | ||||||||
| Molecular_name | C09G9.6 | ||||||||
| C09G9.6.1 | |||||||||
| CE03005 | |||||||||
| Other_name | moe-1 | ||||||||
| CELE_C09G9.6 | Accession_evidence | NDB | BX284604 | ||||||
| Public_name | oma-1 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:33 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | oma | ||||||||
| Allele (56) | |||||||||
| Strain | WBStrain00035069 | ||||||||
| WBStrain00035066 | |||||||||
| WBStrain00035067 | |||||||||
| WBStrain00035068 | |||||||||
| WBStrain00040433 | |||||||||
| WBStrain00040434 | |||||||||
| WBStrain00048324 | |||||||||
| WBStrain00052677 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (55) | |||||||||
| Contained_in_operon | CEOP4312 | ||||||||
| Ortholog (51) | |||||||||
| Paralog (20) | |||||||||
| Structured_description | Concise_description | oma-1 encodes a zinc finger protein of the TIS11 finger type that is paralogous to OMA-2; while either oma-1 or oma-2 individually have no obvious mutant phenotype, oma-1 and oma-2 doubly mutant animals show defects in oocyte maturation, indicating that the two genes function redundantly in this process; whereas normal oocytes are released from meiotic prophase I arrest during oocyte maturation, oma-1;oma-2 mutant oocytes initiate, but fail to complete, maturation, arresting at a defined point in meiotic prophase I; the meiotic arrest of oma-1;oma-2 mutant oocytes is suppressed by wee-1.3(RNAi), implying that progression through meiotic prophase I is critically dependent on inhibition of WEE-1.3 by either OMA-1 or OMA-2; OMA-1 is expressed primarily in maturing oocytes, is cytoplasmic and visible prior to cellularization. | Paper_evidence | WBPaper00005198 | |||||
| Curator_confirmed | WBPerson1843 | ||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 19 Mar 2012 00:00:00 | ||||||||
| Automated_description | Enables mRNA 3'-UTR AU-rich region binding activity and mRNA regulatory element binding translation repressor activity. Involved in several processes, including negative regulation of cell differentiation; oocyte development; and regulation of reproductive process. Located in P granule and centrosome. Part of messenger ribonucleoprotein complex. Expressed in several structures, including head muscle; neurons; oocyte; somatic nervous system; and vulva. Is an ortholog of human ZFP36L1 (ZFP36 ring finger protein like 1) and ZFP36L2 (ZFP36 ring finger protein like 2). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | EFO:MONDO:0014769 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:1108) | ||||
| Molecular_info | Corresponding_CDS | C09G9.6 | |||||||
| Corresponding_transcript | C09G9.6.1 | ||||||||
| Other_sequence | XIC01512_1 | ||||||||
| HG11531 | |||||||||
| XI03775 | |||||||||
| SRC08713_1 | |||||||||
| FC813056.1 | |||||||||
| Associated_feature (15) | |||||||||
| Gene_product_binds | WBsf034245 | ||||||||
| Transcription_factor | WBTranscriptionFactor000116 | ||||||||
| Experimental_info | RNAi_result (29) | ||||||||
| Expr_pattern (16) | |||||||||
| Drives_construct (13) | |||||||||
| Construct_product (14) | |||||||||
| Antibody | WBAntibody00000486 | ||||||||
| WBAntibody00000547 | |||||||||
| WBAntibody00001073 | |||||||||
| WBAntibody00001074 | |||||||||
| WBAntibody00001087 | |||||||||
| WBAntibody00001664 | |||||||||
| WBAntibody00002447 | |||||||||
| Microarray_results (20) | |||||||||
| Expression_cluster (207) | |||||||||
| Interaction (354) | |||||||||
| WBProcess | WBbiopr:00000068 | ||||||||
| WBbiopr:00000073 | |||||||||
| Map_info | Map | IV | Position | 3.99916 | Error | 0.001096 | |||
| Positive | Positive_clone | C09G9 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | 2_point | 7138 | |||||||
| Multi_point | 4054 | ||||||||
| 4056 | |||||||||
| 4064 | |||||||||
| 4065 | |||||||||
| Reference (94) | |||||||||
| Picture | WBPicture0000013094 | ||||||||
| Remark | Weak rescue of the zu405 embryonic lethality [Lin, R][021017 ck1] | ||||||||
| Sequence connection based on Lin, R [021017 ck1] | |||||||||
| Sequence connection from [Shimada M], [krb 020711] | |||||||||
| Postitive method is weak rescue of the zu405 embryonic lethality | |||||||||
| Method | Gene |
