WormBase Tree Display for Gene: WBGene00003865
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| WBGene00003865 | SMap | S_parent | Sequence | ZC513 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | oma-2 | Person_evidence | WBPerson374 | |||||
| Sequence_name | ZC513.6 | ||||||||
| Molecular_name | ZC513.6 | ||||||||
| ZC513.6.1 | |||||||||
| CE07613 | |||||||||
| Other_name | dao-7 | ||||||||
| moe-2 | |||||||||
| CELE_ZC513.6 | Accession_evidence | NDB | BX284605 | ||||||
| Public_name | oma-2 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:33 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | oma | ||||||||
| Allele (32) | |||||||||
| Strain | WBStrain00035068 | ||||||||
| WBStrain00035072 | |||||||||
| WBStrain00024300 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (32) | |||||||||
| Contained_in_operon | CEOP5176 | ||||||||
| CEOP5546 | |||||||||
| Ortholog (51) | |||||||||
| Paralog (20) | |||||||||
| Structured_description | Concise_description | oma-2 encodes a zinc finger protein of the TIS11 finger type that is paralogous to OMA-1; while either oma-1 or oma-2 individually have no obvious mutant phenotype, oma-1 and oma-2 doubly mutant animals show defects in oocyte maturation, indicating that the two genes function redundantly in this process; whereas normal oocytes are released from meiotic prophase I arrest during oocyte maturation, oma-1;oma-2 mutant oocytes initiate, but fail to complete, maturation, arresting at a defined point in meiotic prophase I; the meiotic arrest of oma-1;oma-2 mutant oocytes is suppressed by wee-1.3(RNAi), implying that progression through meiotic prophase I is critically dependent on inhibition of WEE-1.3 by either OMA-1 or OMA-2; OMA-2 is expressed primarily in maturing oocytes, is cytoplasmic and visible in oocytes after cellularization. | Paper_evidence | WBPaper00005198 | |||||
| Curator_confirmed | WBPerson1843 | ||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 19 Mar 2012 00:00:00 | ||||||||
| Automated_description | Enables mRNA regulatory element binding translation repressor activity. Involved in several processes, including meiotic nuclear membrane disassembly; oocyte development; and regulation of reproductive process. Located in P granule and centrosome. Expressed in several structures, including germ line; head muscle; intestine; oocyte; and somatic nervous system. Is an ortholog of human ZFP36L1 (ZFP36 ring finger protein like 1) and ZFP36L2 (ZFP36 ring finger protein like 2). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | EFO:MONDO:0014769 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:1108) | ||||
| Molecular_info | Corresponding_CDS | ZC513.6 | |||||||
| Corresponding_transcript | ZC513.6.1 | ||||||||
| Other_sequence (12) | |||||||||
| Associated_feature (12) | |||||||||
| Gene_product_binds | WBsf034245 | ||||||||
| Transcription_factor | WBTranscriptionFactor000117 | ||||||||
| Experimental_info | RNAi_result (28) | ||||||||
| Expr_pattern (13) | |||||||||
| Drives_construct | WBCnstr00012898 | ||||||||
| WBCnstr00035820 | |||||||||
| Construct_product | WBCnstr00021255 | ||||||||
| WBCnstr00021811 | |||||||||
| WBCnstr00035820 | |||||||||
| WBCnstr00040188 | |||||||||
| WBCnstr00040189 | |||||||||
| Antibody | WBAntibody00000487 | ||||||||
| WBAntibody00000548 | |||||||||
| WBAntibody00001075 | |||||||||
| WBAntibody00001665 | |||||||||
| WBAntibody00002447 | |||||||||
| Microarray_results (19) | |||||||||
| Expression_cluster (246) | |||||||||
| Interaction (316) | |||||||||
| WBProcess | WBbiopr:00000068 | ||||||||
| Map_info | Map | V | Position | 1.00434 | Error | 0.000337 | |||
| Positive | Positive_clone | C09G9 | |||||||
| ZC513 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||||
| Mapping_data | Multi_point | 4560 | |||||||
| 5433 | |||||||||
| Pseudo_map_position | |||||||||
| Reference (58) | |||||||||
| Picture | WBPicture0000013094 | ||||||||
| Remark | Sequence connection based on Lin, R [021017 ck1] | ||||||||
| Sequence connection from [Shimada M], [krb 020711] | |||||||||
| dao-7 was other_name of moe-2, which is now merged into oma-2 [021111 ck1] | |||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
