WormBase Tree Display for Gene: WBGene00020307
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WBGene00020307 | SMap | S_parent | Sequence | T07D3 | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 1 | |||||||
Name | Sequence_name | T07D3.4 | |||||||
Molecular_name | T07D3.4a | ||||||||
T07D3.4a.1 | |||||||||
CE13361 | |||||||||
T07D3.4b | |||||||||
CE51164 | |||||||||
T07D3.4b.1 | |||||||||
Other_name | CELE_T07D3.4 | Accession_evidence | NDB | BX284602 | |||||
Public_name | T07D3.4 | ||||||||
DB_info | Database (10) | ||||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 28 May 2004 13:31:02 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Allele (167) | |||||||||
Strain | WBStrain00031550 | ||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation | 00001837 | ||||||||
Ortholog (57) | |||||||||
Paralog | WBGene00011554 | Caenorhabditis elegans | From_analysis | TreeFam | |||||
Inparanoid_8 | |||||||||
Panther | |||||||||
WormBase-Compara | |||||||||
WBGene00017877 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
Inparanoid_8 | |||||||||
WBGene00020924 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
Inparanoid_8 | |||||||||
Panther | |||||||||
WormBase-Compara | |||||||||
WBGene00021249 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
Inparanoid_8 | |||||||||
Panther | |||||||||
WormBase-Compara | |||||||||
WBGene00020309 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
Inparanoid_8 | |||||||||
WBGene00020308 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
WBGene00020927 | Caenorhabditis elegans | From_analysis | Panther | ||||||
WormBase-Compara | |||||||||
WBGene00045475 | Caenorhabditis elegans | From_analysis | Panther | ||||||
Structured_description | Concise_description | T07D3.4 is orthologous to the human gene, Fukutin (FKTN, also called FCMD). | Paper_evidence | WBPaper00038491 | |||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson1823 | |||||||||
WBPerson567 | |||||||||
Date_last_updated | 07 Jun 2012 00:00:00 | ||||||||
Automated_description | Predicted to be involved in protein glycosylation. Human ortholog(s) of this gene implicated in Fukuyama congenital muscular dystrophy; Walker-Warburg syndrome; autosomal recessive limb-girdle muscular dystrophy type 2L; autosomal recessive limb-girdle muscular dystrophy type 2M; dilated cardiomyopathy (multiple); and muscular dystrophy-dystroglycanopathy type B4. Is an ortholog of human FKTN (fukutin). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Disease_info | Potential_model | DOID:0050560 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3622) | ||||
DOID:0050559 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3622) | ||||||
DOID:0110443 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3622) | ||||||
DOID:9884 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3622) | ||||||
DOID:0112379 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3622) | ||||||
DOID:0110296 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3622) | ||||||
DOID:0110444 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3622) | ||||||
DOID:0110284 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3622) | ||||||
Disease_relevance | The human ortholog of elegans TO7D3.4, Fukutin, is required for normal glycosylation of the cell surface laminin receptor, alpha-dystroglycan; mutations in Fukutin cause cardiomyopathy and Fukuyama-type congenital muscular dystrophy (FCMD), an inherited condition that predominantly affects the muscles, brain, and eyes, due to weakness and wasting of skeletal muscles. | Homo sapiens | Accession_evidence | OMIM | 611615 | ||||
253800 | |||||||||
613152 | |||||||||
611588 | |||||||||
607440 | |||||||||
Curator_confirmed | WBPerson324 | ||||||||
Date_last_updated | 11 Jun 2012 00:00:00 | ||||||||
Molecular_info | Corresponding_CDS | T07D3.4a | |||||||
T07D3.4b | |||||||||
Corresponding_transcript | T07D3.4a.1 | ||||||||
T07D3.4b.1 | |||||||||
Other_sequence | Oden_isotig15156 | ||||||||
Oden_isotig21890 | |||||||||
Dviv_isotig31365 | |||||||||
Associated_feature | WBsf643929 | ||||||||
WBsf643930 | |||||||||
WBsf986513 | |||||||||
WBsf986514 | |||||||||
WBsf986515 | |||||||||
WBsf1011453 | |||||||||
WBsf1011454 | |||||||||
WBsf220796 | |||||||||
Experimental_info | RNAi_result | WBRNAi00035302 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00052752 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00018361 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00115898 | Inferred_automatically | RNAi_primary | |||||||
Expr_pattern | Expr1013786 | ||||||||
Expr1038847 | |||||||||
Expr1156361 | |||||||||
Expr2005965 | |||||||||
Expr2024181 | |||||||||
Drives_construct | WBCnstr00025231 | ||||||||
Construct_product | WBCnstr00025231 | ||||||||
Microarray_results (15) | |||||||||
Expression_cluster (148) | |||||||||
Interaction | WBInteraction000389723 | ||||||||
WBInteraction000446865 | |||||||||
Map_info (2) | |||||||||
Reference (3) | |||||||||
Method | Gene |