Enriched in several structures, including Z1.p; body wall muscle cell; germ line; germline precursor cell; and male distal tip cell based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including skn-1; daf-12; and hsf-1 based on tiling array; RNA-seq; and microarray studies. Is affected by thirteen chemicals including aldicarb; rotenone; and D-glucose based on microarray and RNA-seq studies. Human ortholog(s) of this gene implicated in spondyloepimetaphyseal dysplasia, Sponastrime type. Human TONSL enables histone binding activity and histone reader activity. Is predicted to encode a protein with the following domains: Ankyrin repeats (3 copies); Ankyrin repeat; Ankyrin repeats (many copies); Leucine-rich repeat domain superfamily; Ankyrin repeat-containing domain superfamily; Tetratricopeptide-like helical domain superfamily; Putative ankyrin repeat domain-containing protein 31; and Phosphorylation site. Is an ortholog of human TONSL (tonsoku like, DNA repair protein).
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.