gar-1 encodes a G protein-linked muscarinic acetylcholine receptor; though gar-1 is most closely related to muscarinic acetylcholine receptors (mAChR), it is pharmacologically distinct from them in its response to certain ligands; gar-1 gene transcripts are expressed at all developmental stages; the GAR-1-GFP fusion protein is expressed in some head neurons and in the PVM neuron; electrophysiological studies indicate that gar-1 couples to the inhibitory subunit of G proteins and not to Gs or to Go/Gq.
Enables G protein-coupled acetylcholine receptor activity. Involved in cholinergic synaptic transmission. Located in postsynaptic membrane. Expressed in PVM and head neurons.
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.