WormBase Tree Display for Gene: WBGene00001427
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WBGene00001427 | SMap | S_parent | Sequence | Y18D10A | |||
---|---|---|---|---|---|---|---|
Identity (6) | |||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | fkb | ||||||
Allele (15) | |||||||
Strain | WBStrain00032903 | ||||||
RNASeq_FPKM (74) | |||||||
GO_annotation | 00099491 | ||||||
00099492 | |||||||
00099493 | |||||||
00099494 | |||||||
00099495 | |||||||
00099496 | |||||||
00099497 | |||||||
00108693 | |||||||
Contained_in_operon | CEOP1903 | ||||||
Ortholog (34) | |||||||
Paralog | WBGene00001426 | Caenorhabditis elegans | From_analysis | Panther | |||
WormBase-Compara | |||||||
WBGene00001431 | Caenorhabditis elegans | From_analysis | Panther | ||||
WormBase-Compara | |||||||
WBGene00001433 | Caenorhabditis elegans | From_analysis | Panther | ||||
WormBase-Compara | |||||||
WBGene00001428 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||
WBGene00001429 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||
WBGene00001430 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||
WBGene00001432 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||
Structured_description | Concise_description | fkb-2 encodes a peptidylprolyl cis/trans isomerase homologous to the mammalian FK506 immunosuppressant-binding protein 1A (FKBP1A, OMIM:186945, mutations associated with myocardial noncompaction); by homology, FKB-2 could function in a number of processes including protein folding, signal transduction, and regulation of muscle contraction; however, the precise role of FKB-2 in C. elegans development and/or behavior is not yet known,. | Paper_evidence | WBPaper00004285 | |||
Curator_confirmed | WBPerson1843 | ||||||
Date_last_updated | 17 Jun 2004 00:00:00 | ||||||
Automated_description | Predicted to enable peptidyl-prolyl cis-trans isomerase activity. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in Graves' disease. Is an ortholog of human FKBP1A (FKBP prolyl isomerase 1A); FKBP1B (FKBP prolyl isomerase 1B); and FKBP1C (FKBP prolyl isomerase family member 1C). | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Disease_info | Potential_model | DOID:12361 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3712) | ||
Molecular_info | Corresponding_CDS | Y18D10A.19 | |||||
Corresponding_CDS_history | Y18D10A.19a:wp118 | ||||||
Y18D10A.19b:wp118 | |||||||
Y18D10A.19c:wp118 | |||||||
Corresponding_transcript | Y18D10A.19.1 | ||||||
Other_sequence (146) | |||||||
Associated_feature | WBsf976592 | ||||||
WBsf976593 | |||||||
WBsf976594 | |||||||
WBsf981120 | |||||||
WBsf985723 | |||||||
WBsf985724 | |||||||
WBsf985725 | |||||||
WBsf218655 | |||||||
Experimental_info | RNAi_result | WBRNAi00036695 | Inferred_automatically | RNAi_primary | |||
Expr_pattern | Expr16136 | ||||||
Expr1025484 | |||||||
Expr1030852 | |||||||
Expr1159118 | |||||||
Expr2011796 | |||||||
Expr2030034 | |||||||
Microarray_results (18) | |||||||
Expression_cluster (150) | |||||||
Interaction (114) | |||||||
Map_info | Map | I | Position | 14.2167 | Error | 0.004655 | |
Positive | Positive_clone | Y18D10A | Inferred_automatically | From sequence, transcript, pseudogene data | |||
Pseudo_map_position | |||||||
Reference | WBPaper00004285 | ||||||
WBPaper00026884 | |||||||
WBPaper00038491 | |||||||
WBPaper00055090 | |||||||
WBPaper00063935 | |||||||
WBPaper00064046 | |||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||
Method | Gene |