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WormBase Tree Display for Gene: WBGene00004346

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Name Class

WBGene00004346SMapS_parentSequenceCHROMOSOME_II
IdentityVersion1
NameCGC_namergs-3Person_evidenceWBPerson330
Sequence_nameC29H12.3
Molecular_name (13)
Other_nameCELE_C29H12.3Accession_evidenceNDBBX284602
Public_namergs-3
DB_infoDatabaseAceViewgene2G399
WormQTLgeneWBGene00004346
WormFluxgeneWBGene00004346
NDBlocus_tagCELE_C29H12.3
PanthergeneCAEEL|WormBase=WBGene00004346|UniProtKB=Q18312
familyPTHR10845
NCBIgene174020
RefSeqproteinNM_062822.4
NM_001393090.1
NM_182096.6
SwissProtUniProtAccQ18312
TrEMBLUniProtAccQ5DX43
Q8MQB2
UniProt_GCRPUniProtAccQ18312
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:35WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classrgs
Allele (114)
StrainWBStrain00026361
WBStrain00032471
RNASeq_FPKM (74)
GO_annotation00060895
00060896
00060897
00060898
00060899
00060900
00060901
Ortholog (28)
ParalogWBGene00004344Caenorhabditis elegansFrom_analysisPanther
WBGene00004345Caenorhabditis elegansFrom_analysisPanther
WBGene00004350Caenorhabditis elegansFrom_analysisPanther
WBGene00004347Caenorhabditis elegansFrom_analysisPanther
WBGene00004354Caenorhabditis elegansFrom_analysisPanther
WBGene00004353Caenorhabditis elegansFrom_analysisPanther
Structured_descriptionConcise_descriptionrgs-3 encodes three proteins containing two RGS (regulator of G protein signaling) domains, the more C-terminal of which is most similar to those of the mammalian brain-specific RGS, RGS8; rgs-3 activity is required for normal G protein-mediated response to a number of sensory stimuli, including odorants, high osmolarity, and nose touch off food; genetic analyses indicate that RGS-3 functions to decrease G protein signaling in sensory neurons and increase glutamatergic synaptic transmission from sensory to interneurons; RGS-3::GFP fusion proteins are expressed exclusively in nine pairs of sensory neurons from late stages of embryogenesis through adulthood.Paper_evidenceWBPaper00028963
Curator_confirmedWBPerson48
WBPerson1843
Date_last_updated24 Apr 2007 00:00:00
Automated_descriptionInvolved in chemosensory behavior and sensory perception of bitter taste. Expressed in amphid neurons and phasmid neurons.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSC29H12.3a
C29H12.3b
C29H12.3c
Corresponding_transcriptC29H12.3a.1
C29H12.3a.2
C29H12.3b.1
C29H12.3b.2
C29H12.3c.1
C29H12.3c.2
C29H12.3c.3
Other_sequence (24)
Associated_feature (13)
Experimental_info (7)
Map_infoMapIIPosition-0.485213Error0.010992
PositivePositive_cloneC29H12Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_dataMulti_point4907
4305
5045
Pseudo_map_position
ReferenceWBPaper00004281
WBPaper00011274
WBPaper00024994
WBPaper00025672
WBPaper00028963
WBPaper00030173
WBPaper00031936
WBPaper00034194
WBPaper00035993
WBPaper00037236
WBPaper00040144
WBPaper00043501
WBPaper00043948
WBPaper00048845
WBPaper00064628
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene