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WormBase Tree Display for Gene: WBGene00017012

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Name Class

WBGene00017012SMapS_parentSequenceD1009
IdentityVersion2
NameCGC_nameacs-22Person_evidenceWBPerson237
WBPerson9275
Sequence_nameD1009.1
Molecular_nameD1009.1a
D1009.1a.1
CE04285
D1009.1c
CE51329
D1009.1d
CE51246
D1009.1c.1
D1009.1d.1
Other_nameCELE_D1009.1Accession_evidenceNDBBX284606
Public_nameacs-22
DB_infoDatabaseAceViewgeneXJ557
WormQTLgeneWBGene00017012
WormFluxgeneWBGene00017012
NDBlocus_tagCELE_D1009.1
PanthergeneCAEEL|WormBase=WBGene00017012|UniProtKB=Q18916
familyPTHR43107
NCBIgene181138
RefSeqproteinNM_001392815.1
NM_001322629.4
NM_077108.6
TrEMBLUniProtAccQ18916
A0A131MBB2
A0A131MB92
UniProt_GCRPUniProtAccQ18916
SpeciesCaenorhabditis elegans
HistoryVersion_change128 May 2004 13:30:58WBPerson1971EventImportedInitial conversion from CDS class of stlace from WS125
213 Mar 2009 14:10:25WBPerson9133Name_changeCGC_nameacs-22
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classacs
Allele (144)
StrainWBStrain00004763
RNASeq_FPKM (74)
GO_annotation00001951
00001952
00001953
00001954
00001955
00001956
00001957
00062816
Ortholog (44)
ParalogWBGene00009218Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00003179Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00007082Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00007228Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00008669Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00009106Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00011173Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00013575Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00016108Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00016324Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00016716Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00018152Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00019920Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00020343Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00020634Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00022037Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00022849Caenorhabditis elegansFrom_analysisWormBase-Compara
Structured_descriptionConcise_descriptionacs-22 encodes a protein homologous to the mammalian FATP1 and FATP4 fatty acid transport proteins (FATP)/very long chain fatty acid acyl-CoA synthetases; acs-22 functions redundantly with acs-20 to regulate formation of the cuticle surface barrier that prevents penetration of small molecules; acs-22 may affect cuticle development via its role in incorporation of very long chain fatty acids, but not other fatty acids, into sphingomyelin; an acs-22::gfp promoter fusion is expressed strongly in the intestine, with weaker expression seen in the pharynx, head neurons, and hypodermis.Paper_evidenceWBPaper00035868
Curator_confirmedWBPerson1843
Date_last_updated03 Feb 2010 00:00:00
Automated_descriptionPredicted to enable long-chain fatty acid transporter activity and long-chain fatty acid-CoA ligase activity. Predicted to be involved in triglyceride homeostasis. Located in endoplasmic reticulum. Expressed in head neurons; hypodermis; and pharynx. Human ortholog(s) of this gene implicated in obesity. Is an ortholog of human SLC27A1 (solute carrier family 27 member 1) and SLC27A4 (solute carrier family 27 member 4).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:9970Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:10998)
Molecular_infoCorresponding_CDSD1009.1a
D1009.1c
D1009.1d
Corresponding_CDS_historyD1009.1b:wp271
Corresponding_transcriptD1009.1a.1
D1009.1c.1
D1009.1d.1
Other_sequence (52)
Associated_feature (16)
Experimental_infoRNAi_resultWBRNAi00043335Inferred_automaticallyRNAi_primary
WBRNAi00012490Inferred_automaticallyRNAi_primary
WBRNAi00030314Inferred_automaticallyRNAi_primary
WBRNAi00092595Inferred_automaticallyRNAi_primary
Expr_patternExpr8894
Expr1020922
Expr1037310
Expr1147315
Expr2009212
Expr2027449
Drives_constructWBCnstr00013588
WBCnstr00022751
WBCnstr00027639
Construct_productWBCnstr00014925
WBCnstr00022756
WBCnstr00027639
Microarray_results (28)
Expression_cluster (202)
Interaction (87)
Map_infoMapXPosition0.449566Error0.000197
PositivePositive_cloneD1009Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00033537
WBPaper00035868
WBPaper00036607
WBPaper00038491
WBPaper00041485
WBPaper00042257
WBPaper00048892
WBPaper00049625
WBPaper00054769
WBPaper00055090
WBPaper00056988
WBPaper00057257
WBPaper00059010
WBPaper00061653
WBPaper00065026
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene