WormBase Tree Display for Gene: WBGene00006735

WBGene00006735 SMap: S_parent: Sequence: C26E6
  Identity: Version: 1
    Name: CGC_name: ula-1 Person_evidence: WBPerson89
      Sequence_name: C26E6.8
      Molecular_name: C26E6.8a
        C26E6.8a.1
        CE29678
        C26E6.8b
        CE52486
        C26E6.8b.1
      Other_name: CELE_C26E6.8 Accession_evidence: NDB BX284603
      Public_name: ula-1
    DB_info: Database: AceView gene 3G8
        WormQTL gene WBGene00006735
        WormFlux gene WBGene00006735
        NDB locus_tag CELE_C26E6.8
        Panther gene CAEEL|WormBase=WBGene00006735|UniProtKB=Q18217
          family PTHR10953
        NCBI gene 266650
        RefSeq protein NM_065636.5
            NM_001361710.4
        SwissProt UniProtAcc Q18217
        TrEMBL UniProtAcc A0A2K5ATU0
        UniProt_GCRP UniProtAcc Q18217
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:41 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: ula
    Allele (24)
    Strain: WBStrain00036447
    RNASeq_FPKM (74)
    GO_annotation: 00003109
      00003110
      00003111
      00060518
      00060519
      00060520
      00060521
      00114705
      00114706
      00114707
    Contained_in_operon: CEOP3240
    Ortholog: WBGene00061661 Caenorhabditis remanei From_analysis (4)
      WBGene00037655 Caenorhabditis briggsae From_analysis (5)
      WBGene00153982 Caenorhabditis brenneri From_analysis (4)
      WBGene00133281 Caenorhabditis japonica From_analysis (2)
      WBGene00094785 Pristionchus pacificus From_analysis (2)
      WBGene00222667 Brugia malayi From_analysis: WormBase-Compara
      CBOVI.g5121 Caenorhabditis bovis From_analysis: WormBase-Compara
      CSP21.g12492 Caenorhabditis parvicauda From_analysis: WormBase-Compara
      CSP26.g1544 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP28.g19886 Caenorhabditis panamensis From_analysis: WormBase-Compara
      CSP29.g11579 Caenorhabditis becei From_analysis: WormBase-Compara
      CSP31.g5597 Caenorhabditis uteleia From_analysis: WormBase-Compara
      CSP32.g2715 Caenorhabditis sulstoni From_analysis: WormBase-Compara
      CSP38.g6625 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      CSP39.g4080 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP40.g1191 Caenorhabditis tribulationis From_analysis: WormBase-Compara
      Cni-ula-1 Caenorhabditis nigoni From_analysis: WormBase-Compara
      Csp11.Scaffold629.g14364 Caenorhabditis tropicalis From_analysis: WormBase-Compara
      Csp5_scaffold_00253.g8013 Caenorhabditis sinica From_analysis: WormBase-Compara
      FL83_23680 Caenorhabditis latens From_analysis: WormBase-Compara
      GCK72_009982 Caenorhabditis remanei From_analysis: WormBase-Compara
      Pan_g23275 Panagrellus redivivus From_analysis: WormBase-Compara
      Sp34_30056000 Caenorhabditis inopinata From_analysis: WormBase-Compara
      chrIII_pilon.g7592 Caenorhabditis elegans From_analysis: WormBase-Compara
      nigoni.pc_2016.07.11_023.g28466 Caenorhabditis nigoni From_analysis: WormBase-Compara
      WBGene00246027 Onchocerca volvulus From_analysis: WormBase-Compara
      WBGene00296748 Trichuris muris From_analysis: WormBase-Compara
      WBGene00301677 Trichuris muris From_analysis: WormBase-Compara
      SGD:S000005924 Saccharomyces cerevisiae From_analysis (7)
      FB:FBgn0261112 Drosophila melanogaster From_analysis (9)
      ZFIN:ZDB-GENE-040426-1552 Danio rerio From_analysis (9)
      HGNC:621 Homo sapiens From_analysis (9)
      MGI:2384561 Mus musculus From_analysis (8)
      RGD:619945 Rattus norvegicus From_analysis (9)
    Paralog: WBGene00000142 Caenorhabditis elegans From_analysis (2)
      WBGene00004341 Caenorhabditis elegans From_analysis (2)
      WBGene00006699 Caenorhabditis elegans From_analysis (2)
      WBGene00006700 Caenorhabditis elegans From_analysis (2)
      WBGene00010882 Caenorhabditis elegans From_analysis (2)
      WBGene00020184 Caenorhabditis elegans From_analysis (2)
      WBGene00018357 Caenorhabditis elegans From_analysis (2)
    Structured_description: Concise_description: The ula-1 gene encodes a component of the enzyme that activates NED-8, which in turn is a ubiquitin-like protein whose conjugating enzyme is UBC-12. Paper_evidence: WBPaper00004363
          Curator_confirmed: WBPerson567
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Predicted to enable NEDD8 activating enzyme activity. Involved in negative regulation of DNA damage response, signal transduction by p53 class mediator. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in Alzheimer's disease. Is an ortholog of human NAE1 (NEDD8 activating enzyme E1 subunit 1). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:10652 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:621)
  Molecular_info: Corresponding_CDS: C26E6.8a
      C26E6.8b
    Corresponding_transcript: C26E6.8a.1
      C26E6.8b.1
    Other_sequence (22)
    Associated_feature: WBsf226607
      WBsf226608
  Experimental_info: RNAi_result (35)
    Expr_pattern: Expr1018502
      Expr1032810
      Expr1145317
      Expr2017820
      Expr2035957
    Drives_construct: WBCnstr00034185
    Construct_product: WBCnstr00034185
    Microarray_results (20)
    Expression_cluster (82)
    Interaction (96)
  Map_info: Map: III Position: -2.36589 Error: 0.002572
    Positive: Positive_clone: C26E6 Inferred_automatically: From CDS info
            From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00004363
    WBPaper00005337
    WBPaper00017727
    WBPaper00031605
    WBPaper00033469
    WBPaper00038491
    WBPaper00055090
  Remark: Sequence connection from [Jones D, Crowe E, Stevens TA, Candido EPM], 02/06/10 krb.
    Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene