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WormBase Tree Display for Gene: WBGene00009221

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Name Class

WBGene00009221SMapS_parentSequenceF28F8
IdentityVersion2
NameCGC_nameacs-2Person_evidenceWBPerson7030
WBPerson2239
WBPerson237
Sequence_nameF28F8.2
Molecular_nameF28F8.2
F28F8.2.1
CE09756
Other_nameCELE_F28F8.2Accession_evidenceNDBBX284605
Public_nameacs-2
DB_infoDatabaseAceViewgene5Q49
WormQTLgeneWBGene00009221
WormFluxgeneWBGene00009221
NDBlocus_tagCELE_F28F8.2
PanthergeneCAEEL|WormBase=WBGene00009221|UniProtKB=O18693
familyPTHR43201
NCBIgene3565680
RefSeqproteinNM_074468.6
TREEFAMTREEFAM_IDTF313466
TrEMBLUniProtAccO18693
UniProt_GCRPUniProtAccO18693
SpeciesCaenorhabditis elegans
HistoryVersion_change126 May 2004 16:54:50WBPerson1971EventImportedInitial conversion from CDS class of WS125
223 Mar 2005 15:36:05WBPerson2970Name_changeCGC_nameacs-2
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classacs
Allele (76)
StrainWBStrain00032584
Component_of_genotypeWBGenotype00000151
WBGenotype00000152
WBGenotype00000153
WBGenotype00000154
RNASeq_FPKM (74)
GO_annotation00031987
00031988
00031989
00031990
Ortholog (38)
ParalogWBGene00016849Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00018269Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00018579Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00018488Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00006351Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00007969Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00012356Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00013440Caenorhabditis elegansFrom_analysisWormBase-Compara
Structured_descriptionConcise_descriptionacs-2 encodes an acyl-CoA synthetase; by homology, ACS-2 is predicted to catalyze conversion of a fatty acid to Acyl-CoA for subsequent beta oxidation; accordingly, loss of acs-2 activity via RNAi results in defects in fat metabolism; an ACS-2::GFP reporter fusion protein is widely expressed and appears to localize to mitochondria; acs-2 expression is positively regulated by the NHR-49 nuclear hormone receptor.Paper_evidenceWBPaper00005655
WBPaper00025114
Curator_confirmedWBPerson1843
Date_last_updated17 Mar 2009 00:00:00
Automated_descriptionPredicted to enable medium-chain fatty acid-CoA ligase activity. Involved in fatty acid metabolic process. Located in mitochondrion. Expressed in body wall musculature; hypodermis; intestine; neurons; and pharynx. Is an ortholog of human ACSF2 (acyl-CoA synthetase family member 2).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoExperimental_modelDOID:3146Homo sapiensPaper_evidenceWBPaper00039810
Curator_confirmedWBPerson324
Date_last_updated31 Jul 2023 00:00:00
Molecular_infoCorresponding_CDSF28F8.2
Corresponding_transcriptF28F8.2.1
Other_sequence (21)
Associated_featureWBsf662130
WBsf1002313
WBsf1021034
WBsf233036
Experimental_infoRNAi_result (11)
Expr_patternExpr3469
Expr3780
Expr1014898
Expr1034024
Expr1149753
Expr2009213
Expr2027450
Drives_constructWBCnstr00011406
WBCnstr00011655
WBCnstr00021644
Construct_productWBCnstr00011406
WBCnstr00011655
Microarray_results (25)
Expression_cluster (473)
InteractionWBInteraction000005474
WBInteraction000005475
WBInteraction000005592
WBInteraction000005659
WBInteraction000005660
WBInteraction000005778
WBInteraction000005779
WBInteraction000005780
WBInteraction000008982
WBInteraction000160483
WBInteraction000180233
WBInteraction000180988
WBInteraction000210534
WBInteraction000217201
WBInteraction000222685
WBInteraction000227482
WBInteraction000228823
WBInteraction000230698
WBInteraction000233452
WBInteraction000247642
WBInteraction000251131
WBInteraction000266387
WBInteraction000304101
WBInteraction000324742
WBInteraction000334507
WBInteraction000336993
WBInteraction000342390
WBInteraction000346699
WBInteraction000346913
WBInteraction000355067
WBInteraction000355896
WBInteraction000357329
WBInteraction000359922
WBInteraction000375907
WBInteraction000389679
WBInteraction000416086
WBInteraction000426551
WBInteraction000441602
WBInteraction000446243
WBInteraction000448922
WBInteraction000450446
WBInteraction000456371
WBInteraction000501312
WBInteraction000501313
WBInteraction000501314
WBInteraction000502078
WBInteraction000503596
WBInteraction000504203
WBInteraction000504335
WBInteraction000504914
WBInteraction000505200
WBInteraction000517796
WBInteraction000517801
WBInteraction000517804
WBInteraction000517808
WBInteraction000517886
WBInteraction000519258
WBInteraction000519946
WBInteraction000520096
WBInteraction000524507
WBInteraction000524930
WBInteraction000535443
WBInteraction000541065
WBInteraction000541067
WBInteraction000542657
WBInteraction000549571
WBInteraction000560031
WBInteraction000563294
WBInteraction000563616
WBInteraction000571134
WBInteraction000571950
WBInteraction000575311
WBInteraction000576203
Map_infoMapVPosition8.35712Error0.005311
PositivePositive_cloneF28F8Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
Reference (52)
PictureWBPicture0000013098
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene