WormBase Tree Display for Gene: WBGene00006735

WBGene00006735 SMap: S_parent: Sequence: C26E6
  Identity: Version: 1
    Name: CGC_name: ula-1 Person_evidence: WBPerson89
      Sequence_name: C26E6.8
      Molecular_name: C26E6.8a
        C26E6.8a.1
        CE29678
        C26E6.8b
        CE52486
        C26E6.8b.1
      Other_name: CELE_C26E6.8 Accession_evidence: NDB BX284603
      Public_name: ula-1
    DB_info: Database: AceView gene 3G8
        WormQTL gene WBGene00006735
        WormFlux gene WBGene00006735
        NDB locus_tag CELE_C26E6.8
        Panther gene CAEEL|WormBase=WBGene00006735|UniProtKB=Q18217
          family PTHR10953
        NCBI gene 266650
        RefSeq protein NM_065636.5
            NM_001361710.4
        SwissProt UniProtAcc Q18217
        TrEMBL UniProtAcc A0A2K5ATU0
        UniProt_GCRP UniProtAcc Q18217
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:41 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: ula
    Allele (24)
    Strain: WBStrain00036447
    RNASeq_FPKM (74)
    GO_annotation: 00003109
      00003110
      00003111
      00060518
      00060519
      00060520
      00060521
      00114705
      00114706
      00114707
    Contained_in_operon: CEOP3240
    Ortholog: WBGene00061661 Caenorhabditis remanei From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00037655 Caenorhabditis briggsae From_analysis: Hillier-set
            OrthoMCL
            OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00153982 Caenorhabditis brenneri From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00133281 Caenorhabditis japonica From_analysis: Inparanoid_8
            WormBase-Compara
      WBGene00094785 Pristionchus pacificus From_analysis: Inparanoid_8
            WormBase-Compara
      WBGene00222667 Brugia malayi From_analysis: WormBase-Compara
      CBOVI.g5121 Caenorhabditis bovis From_analysis: WormBase-Compara
      CSP21.g12492 Caenorhabditis parvicauda From_analysis: WormBase-Compara
      CSP26.g1544 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP28.g19886 Caenorhabditis panamensis From_analysis: WormBase-Compara
      CSP29.g11579 Caenorhabditis becei From_analysis: WormBase-Compara
      CSP31.g5597 Caenorhabditis uteleia From_analysis: WormBase-Compara
      CSP32.g2715 Caenorhabditis sulstoni From_analysis: WormBase-Compara
      CSP38.g6625 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      CSP39.g4080 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP40.g1191 Caenorhabditis tribulationis From_analysis: WormBase-Compara
      Cni-ula-1 Caenorhabditis nigoni From_analysis: WormBase-Compara
      Csp11.Scaffold629.g14364 Caenorhabditis tropicalis From_analysis: WormBase-Compara
      Csp5_scaffold_00253.g8013 Caenorhabditis sinica From_analysis: WormBase-Compara
      FL83_23680 Caenorhabditis latens From_analysis: WormBase-Compara
      GCK72_009982 Caenorhabditis remanei From_analysis: WormBase-Compara
      Pan_g23275 Panagrellus redivivus From_analysis: WormBase-Compara
      Sp34_30056000 Caenorhabditis inopinata From_analysis: WormBase-Compara
      chrIII_pilon.g7592 Caenorhabditis elegans From_analysis: WormBase-Compara
      nigoni.pc_2016.07.11_023.g28466 Caenorhabditis nigoni From_analysis: WormBase-Compara
      WBGene00246027 Onchocerca volvulus From_analysis: WormBase-Compara
      WBGene00296748 Trichuris muris From_analysis: WormBase-Compara
      WBGene00301677 Trichuris muris From_analysis: WormBase-Compara
      SGD:S000005924 Saccharomyces cerevisiae From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
      FB:FBgn0261112 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      ZFIN:ZDB-GENE-040426-1552 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      HGNC:621 Homo sapiens From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      MGI:2384561 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      RGD:619945 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
    Paralog: WBGene00000142 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00004341 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00006699 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00006700 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00010882 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00020184 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00018357 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
    Structured_description: Concise_description: The ula-1 gene encodes a component of the enzyme that activates NED-8, which in turn is a ubiquitin-like protein whose conjugating enzyme is UBC-12. Paper_evidence: WBPaper00004363
          Curator_confirmed: WBPerson567
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Predicted to enable NEDD8 activating enzyme activity. Involved in negative regulation of DNA damage response, signal transduction by p53 class mediator. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in Alzheimer's disease. Is an ortholog of human NAE1 (NEDD8 activating enzyme E1 subunit 1). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:10652 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:621)
  Molecular_info: Corresponding_CDS: C26E6.8a
      C26E6.8b
    Corresponding_transcript: C26E6.8a.1
      C26E6.8b.1
    Other_sequence (22)
    Associated_feature: WBsf226607
      WBsf226608
  Experimental_info: RNAi_result (35)
    Expr_pattern: Expr1018502
      Expr1032810
      Expr1145317
      Expr2017820
      Expr2035957
    Drives_construct: WBCnstr00034185
    Construct_product: WBCnstr00034185
    Microarray_results (20)
    Expression_cluster (82)
    Interaction: WBInteraction000008283
      WBInteraction000008284
      WBInteraction000008285
      WBInteraction000008286
      WBInteraction000033150
      WBInteraction000037082
      WBInteraction000043220
      WBInteraction000114479
      WBInteraction000135621
      WBInteraction000135622
      WBInteraction000141757
      WBInteraction000142071
      WBInteraction000146251
      WBInteraction000151835
      WBInteraction000152265
      WBInteraction000160002
      WBInteraction000160284
      WBInteraction000171754
      WBInteraction000179256
      WBInteraction000182162
      WBInteraction000182286
      WBInteraction000185440
      WBInteraction000200303
      WBInteraction000211960
      WBInteraction000212800
      WBInteraction000213486
      WBInteraction000215195
      WBInteraction000229151
      WBInteraction000231082
      WBInteraction000231834
      WBInteraction000235519
      WBInteraction000240544
      WBInteraction000240821
      WBInteraction000246073
      WBInteraction000247134
      WBInteraction000249147
      WBInteraction000257238
      WBInteraction000258226
      WBInteraction000259976
      WBInteraction000269193
      WBInteraction000275879
      WBInteraction000276844
      WBInteraction000278776
      WBInteraction000282603
      WBInteraction000286820
      WBInteraction000293573
      WBInteraction000304575
      WBInteraction000305921
      WBInteraction000308665
      WBInteraction000330843
      WBInteraction000332361
      WBInteraction000337090
      WBInteraction000343164
      WBInteraction000352693
      WBInteraction000362253
      WBInteraction000367056
      WBInteraction000369189
      WBInteraction000371898
      WBInteraction000378556
      WBInteraction000390368
      WBInteraction000394898
      WBInteraction000404907
      WBInteraction000405805
      WBInteraction000410841
      WBInteraction000416762
      WBInteraction000424591
      WBInteraction000427541
      WBInteraction000428446
      WBInteraction000432220
      WBInteraction000435470
      WBInteraction000437645
      WBInteraction000440725
      WBInteraction000442211
      WBInteraction000445502
      WBInteraction000449386
      WBInteraction000453510
      WBInteraction000454695
      WBInteraction000457903
      WBInteraction000461390
      WBInteraction000462405
      WBInteraction000465858
      WBInteraction000467374
      WBInteraction000469129
      WBInteraction000470202
      WBInteraction000470858
      WBInteraction000471095
      WBInteraction000472169
      WBInteraction000474401
      WBInteraction000475072
      WBInteraction000503999
      WBInteraction000557508
      WBInteraction000573608
      WBInteraction000577802
      WBInteraction000579605
      WBInteraction000580477
      WBInteraction000585000
  Map_info: Map: III Position: -2.36589 Error: 0.002572
    Positive: Positive_clone: C26E6 Inferred_automatically: From CDS info
            From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00004363
    WBPaper00005337
    WBPaper00017727
    WBPaper00031605
    WBPaper00033469
    WBPaper00038491
    WBPaper00055090
  Remark: Sequence connection from [Jones D, Crowe E, Stevens TA, Candido EPM], 02/06/10 krb.
    Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene