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WormBase Tree Display for Gene: WBGene00022642

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Name Class

WBGene00022642SMapS_parentSequenceZK6
IdentityVersion2
NameCGC_namelipl-5Person_evidenceWBPerson3759
WBPerson7490
WBPerson545
Sequence_nameZK6.7
Molecular_nameZK6.7a
ZK6.7a.1
CE18444
ZK6.7c
CE50798
ZK6.7d
CE50743
ZK6.7b
ZK6.7c.1
ZK6.7d.1
Other_nameCELE_ZK6.7Accession_evidenceNDBBX284605
Public_namelipl-5
DB_infoDatabase (13)
SpeciesCaenorhabditis elegans
HistoryVersion_change128 May 2004 13:31:06WBPerson1971EventImportedInitial conversion from CDS class of stlace from WS125
219 Jul 2010 13:43:13WBPerson2970Name_changeCGC_namelipl-5
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classlipl
Allele (47)
Strain (2)
RNASeq_FPKM (74)
GO_annotation (14)
Ortholog (66)
ParalogWBGene00008510Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00009773Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00010062Caenorhabditis elegansFrom_analysisTreeFam
Inparanoid_8
Panther
WormBase-Compara
WBGene00013050Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00019376Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00020016Caenorhabditis elegansFrom_analysisTreeFam
Inparanoid_8
Panther
WormBase-Compara
WBGene00021963Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
Structured_descriptionConcise_descriptionlipl-5 encodes a lipase; lipl-5 is expressed in the intestine and its expression is negatively regulated in well-fed animals by MXL-3; lipl-5 expression is induced upon bacterial infection.Paper_evidenceWBPaper00005382
WBPaper00042295
Curator_confirmedWBPerson1843
Date_last_updated19 Jun 2013 00:00:00
Automated_descriptionPredicted to enable hydrolase activity, acting on ester bonds. Involved in defense response to Gram-negative bacterium; lipid homeostasis; and triglyceride catabolic process. Located in lysosome. Expressed in coelomocyte and intestine. Human ortholog(s) of this gene implicated in Wolman disease; autosomal recessive congenital ichthyosis 8; and cholesterol ester storage disease. Is an ortholog of several human genes including LIPA (lipase A, lysosomal acid type); LIPF (lipase F, gastric type); and LIPJ (lipase family member J).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0080217Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:6617)
DOID:14502Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:6617)
DOID:14497Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:6617)
DOID:0060717Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:23452)
Molecular_infoCorresponding_CDSZK6.7a
ZK6.7c
ZK6.7d
Corresponding_CDS_historyZK6.7b:wp248
Corresponding_transcriptZK6.7b
ZK6.7a.1
ZK6.7c.1
ZK6.7d.1
Other_sequence (34)
Associated_featureWBsf999148
WBsf1019064
WBsf231319
WBsf231320
WBsf231321
Experimental_infoRNAi_result (12)
Expr_patternExpr1967
Expr14545
Expr14546
Expr1010508
Expr1162960
Expr2013207
Expr2031439
Drives_constructWBCnstr00041084
Construct_productWBCnstr00041084
Microarray_resultsSMD_ZK6.7
SMD_ZK6.7:2
187925_at
A_12_P107172
GPL13394_WBGene00022642
GPL13914_ZK6.7
GPL14144_ZK6.7a_1165-1224_0.815_52_A
GPL14144_ZK6.7a_901-960_0.871_21_B
GPL19516_CGZ0057108
GPL19516_CGZ0057109
GPL21109_ZK6.7a
GPL3518_CE18444
GPL3518_CE29647
GPL8304_CE_WBGene00022642_A
GPL8673_ZK6_7aP01129
GPL8673_ZK6_7aP01140
GPL8673_ZK6_7aP01152
GPL8673_ZK6_7bP00229
GPL8673_ZK6_7bP00442
GPL8673_ZK6_7bP00818
GPL9450_ZK6.7a
cea2.d.49436
cea2.d.49447
Expression_cluster (289)
InteractionWBInteraction000041956
WBInteraction000041961
WBInteraction000104136
WBInteraction000104137
WBInteraction000134978
WBInteraction000246333
WBInteraction000250640
WBInteraction000262063
WBInteraction000279830
WBInteraction000287861
WBInteraction000290676
WBInteraction000294937
WBInteraction000301430
WBInteraction000309864
WBInteraction000340078
WBInteraction000360912
WBInteraction000373847
WBInteraction000373848
WBInteraction000386191
WBInteraction000392219
WBInteraction000414845
WBInteraction000415927
WBInteraction000419536
WBInteraction000427495
WBInteraction000428378
WBInteraction000433923
WBInteraction000434179
WBInteraction000434707
WBInteraction000442915
WBInteraction000452443
WBInteraction000465038
WBInteraction000472184
WBInteraction000472839
WBInteraction000504590
WBInteraction000520070
WBInteraction000520074
WBInteraction000542657
WBInteraction000584967
WBProcessWBbiopr:00000039
Map_infoMapVPosition-20
PositivePositive_cloneZK6Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
Reference (12)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene