WormBase Tree Display for Gene: WBGene00000445
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WBGene00000445 | SMap | S_parent | Sequence | F29F11 | |||
---|---|---|---|---|---|---|---|
Identity (6) | |||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | ceh | ||||||
Reference_allele | WBVar00239183 | ||||||
Allele (54) | |||||||
Legacy_information | cc8266te : pharyngeal defects, poor feeding, some larval arrest. OA1: pk40tci Encodes protein related (83%) to NK-2 of Drosophila. Candidate binding protein for myo-2 enhancer. ceh-22:lacZ expressed in pharyngeal muscle. [Okkema and Fire 1994] | ||||||
[C.elegansII] cc8266te : pharyngeal defects, poor feeding, some larval arrest. OA1: pk40tci Encodes protein related (83%) to NK-2 of Drosophila.Candidate binding protein for myo-2 enhancer. ceh-22:lacZ expressed in pharyngeal muscle. [Okkema and Fire 1994] | |||||||
Strain | WBStrain00029938 | ||||||
WBStrain00029950 | |||||||
WBStrain00030611 | |||||||
WBStrain00002782 | |||||||
WBStrain00022585 | |||||||
WBStrain00022629 | |||||||
WBStrain00030612 | |||||||
WBStrain00029939 | |||||||
WBStrain00049270 | |||||||
RNASeq_FPKM (74) | |||||||
GO_annotation (22) | |||||||
Ortholog (35) | |||||||
Paralog | WBGene00000428 | Caenorhabditis elegans | From_analysis | Panther | |||
WormBase-Compara | |||||||
WBGene00000434 | Caenorhabditis elegans | From_analysis | Panther | ||||
WormBase-Compara | |||||||
WBGene00000447 | Caenorhabditis elegans | From_analysis | TreeFam | ||||
Panther | |||||||
WormBase-Compara | |||||||
WBGene00000584 | Caenorhabditis elegans | From_analysis | Panther | ||||
WormBase-Compara | |||||||
WBGene00000449 | Caenorhabditis elegans | From_analysis | Panther | ||||
WormBase-Compara | |||||||
WBGene00000450 | Caenorhabditis elegans | From_analysis | Panther | ||||
WormBase-Compara | |||||||
Structured_description | Concise_description | ceh-22 encodes an NK-2 family homeodomain factor homologous to Drosophila TINMAN and vertebrate Nkx2-5 proteins; CEH-22 activates pharyngeal muscle gene expression in combination with PHA-1 and is required for normal pharyngeal development; ceh-22 is the first gene known to be expressed in pharyngeal muscles, being exclusively active in that tissue. | Paper_evidence | WBPaper00005167 | |||
WBPaper00002925 | |||||||
Curator_confirmed | WBPerson1843 | ||||||
WBPerson567 | |||||||
Date_last_updated | 15 Feb 2014 00:00:00 | ||||||
Automated_description | Enables sequence-specific DNA binding activity. Involved in several processes, including gonad morphogenesis; pharyngeal muscle development; and positive regulation of transcription by RNA polymerase II. Located in nucleus. Expressed in several structures, including G1; gonad; neurons; pharyngeal cell; and ventral nerve cord. Used to study cancer. Is an ortholog of human NKX2-2 (NK2 homeobox 2). | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Disease_info | Experimental_model | DOID:162 | Homo sapiens | Paper_evidence | WBPaper00060633 | ||
Curator_confirmed | WBPerson324 | ||||||
Date_last_updated | 24 Jun 2021 00:00:00 | ||||||
Models_disease_asserted | WBDOannot00000949 | ||||||
WBDOannot00000954 | |||||||
WBDOannot00000961 | |||||||
WBDOannot00000962 | |||||||
Molecular_info | Corresponding_CDS | F29F11.5a | |||||
F29F11.5b | |||||||
F29F11.5c | |||||||
F29F11.5d | |||||||
F29F11.5e | |||||||
Corresponding_transcript | F29F11.5a.1 | ||||||
F29F11.5b.1 | |||||||
F29F11.5c.1 | |||||||
F29F11.5d.1 | |||||||
F29F11.5e.1 | |||||||
Other_sequence | Acan_isotig04736 | ||||||
Oden_isotig21208 | |||||||
CBC02288_1 | |||||||
MI05158 | |||||||
MIC04433_1 | |||||||
JI177847.1 | |||||||
Associated_feature (24) | |||||||
Gene_product_binds (135) | |||||||
Transcription_factor | WBTranscriptionFactor000061 | ||||||
Experimental_info | RNAi_result | WBRNAi00071562 | Inferred_automatically | RNAi_primary | |||
WBRNAi00014111 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00031582 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00115657 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00027310 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00069884 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00025316 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00045934 | Inferred_automatically | RNAi_primary | |||||
Expr_pattern (23) | |||||||
Drives_construct (18) | |||||||
Construct_product (13) | |||||||
Antibody | WBAntibody00000082 | ||||||
WBAntibody00000083 | |||||||
Microarray_results (30) | |||||||
Expression_cluster (133) | |||||||
Interaction (111) | |||||||
WBProcess | WBbiopr:00000073 | ||||||
WBbiopr:00000114 | |||||||
Map_info | Map | V | Position | 2.70908 | Error | 0.00321 | |
Well_ordered | |||||||
Positive | Positive_clone | F29F11 | Inferred_automatically | From sequence, transcript, pseudogene data | |||
Y24E3 | |||||||
Y33F10 | |||||||
Y59H10 | |||||||
Y61D5 | |||||||
Mapping_data | Multi_point | 3789 | |||||
Pos_neg_data | 8351 | ||||||
8352 | |||||||
8353 | |||||||
8354 | |||||||
8355 | |||||||
Reference (88) | |||||||
Method | Gene |