WormBase Tree Display for Gene: WBGene00000420
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| WBGene00000420 | SMap | S_parent | Sequence | CHROMOSOME_III | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | ced-6 | Person_evidence | WBPerson261 | |||||
| Sequence_name | F56D2.7 | ||||||||
| Molecular_name | F56D2.7 | ||||||||
| F56D2.7.1 | |||||||||
| CE33657 | |||||||||
| Other_name | CELE_F56D2.7 | Accession_evidence | NDB | BX284603 | |||||
| Public_name | ced-6 | ||||||||
| DB_info | Database | AceView | gene | 3G687 | |||||
| WormQTL | gene | WBGene00000420 | |||||||
| WormFlux | gene | WBGene00000420 | |||||||
| NDB | locus_tag | CELE_F56D2.7 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00000420|UniProtKB=O76337 | |||||||
| family | PTHR11232 | ||||||||
| NCBI | gene | 175773 | |||||||
| RefSeq | protein | NM_065802.10 | |||||||
| SwissProt | UniProtAcc | O76337 | |||||||
| TREEFAM | TREEFAM_ID | TF314159 | |||||||
| UniProt_GCRP | UniProtAcc | O76337 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:20 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | ced | ||||||||
| Allele (45) | |||||||||
| Legacy_information | [C.elegansII] n2095 : programmed cell deaths abnormal, dying cells arrest at highly refractile stage; killer cells fail to engulf target cells; engulfment group A (ced-1,6,7);extensive maternal rescue; no gross phenotype. OA1: n1813.[Ellis et al. 1991; MT] | ||||||||
| [C.elegansII] n2095 : programmed cell deaths abnormal, dying cells arrest at highly refractile stage; killer cells fail to engulf target cells; engulfment group A (ced-1,6,7);extensive maternal rescue; no gross phenotype. OA1: n1813. [Ellis et al. 1991; MT] | |||||||||
| Strain | WBStrain00027133 | ||||||||
| WBStrain00027168 | |||||||||
| WBStrain00027175 | |||||||||
| WBStrain00027176 | |||||||||
| WBStrain00027177 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (20) | |||||||||
| Contained_in_operon | CEOP3310 | ||||||||
| Ortholog (33) | |||||||||
| Paralog | WBGene00003830 | Caenorhabditis elegans | From_analysis | TreeFam | |||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00000894 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00001116 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00009930 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00002176 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | ced-6 encodes an Src homology (SH) 3 and phosphotyrosine-binding (PTB) domain-containing adaptor protein, orthologous to human CED-6/GULP, that is required for cell corpse engulfment during apoptosis; CED-6 is bound by the phosphotyrosine binding motif in the cytoplasmic tail of the transmembrane protein CED-1, and and within phagocytic cells this interaction may be part of a signal transduction pathway that promotes apoptotic cell engulfment. | Paper_evidence | WBPaper00003090 | |||||
| WBPaper00003948 | |||||||||
| WBPaper00005196 | |||||||||
| WBPaper00005200 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
| Automated_description | Enables clathrin adaptor activity and scavenger receptor binding activity. Involved in several processes, including engulfment of apoptotic cell; left/right axis specification; and positive regulation of distal tip cell migration. Located in cytoplasmic side of plasma membrane and phagocytic vesicle. Is an ortholog of human GULP1 (GULP PTB domain containing engulfment adaptor 1). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | F56D2.7 | |||||||
| Corresponding_CDS_history | F56D2.7:wp88 | ||||||||
| F56D2.7:wp234 | |||||||||
| Corresponding_transcript | F56D2.7.1 | ||||||||
| Other_sequence (20) | |||||||||
| Associated_feature | WBsf645185 | ||||||||
| WBsf645186 | |||||||||
| WBsf224966 | |||||||||
| WBsf224967 | |||||||||
| Experimental_info | RNAi_result (14) | ||||||||
| Expr_pattern | Expr4415 | ||||||||
| Expr1021782 | |||||||||
| Expr1030236 | |||||||||
| Expr1152456 | |||||||||
| Expr2009850 | |||||||||
| Expr2028090 | |||||||||
| Drives_construct | WBCnstr00011977 | ||||||||
| WBCnstr00037556 | |||||||||
| Construct_product | WBCnstr00001403 | ||||||||
| WBCnstr00001404 | |||||||||
| WBCnstr00011977 | |||||||||
| WBCnstr00017668 | |||||||||
| WBCnstr00037556 | |||||||||
| Antibody | WBAntibody00002440 | ||||||||
| WBAntibody00003053 | |||||||||
| WBAntibody00003054 | |||||||||
| Microarray_results (21) | |||||||||
| Expression_cluster (124) | |||||||||
| Interaction (99) | |||||||||
| Anatomy_function | WBbtf0059 | ||||||||
| WBProcess | WBbiopr:00000013 | ||||||||
| WBbiopr:00000014 | |||||||||
| WBbiopr:00000015 | |||||||||
| Map_info (4) | |||||||||
| Reference (141) | |||||||||
| Remark | Sequence connection from [Liu QA, Hengartner MO], krb | ||||||||
| Method | Gene |
