dpy-19 encodes a C-mannosyltransferase; DPY-19 is required for mannosylation of the surface receptors MIG-21 and UNC-5, and for correct polarization and migration of the neuroblasts QL and QR.
Enables mannosyltransferase activity. Predicted to be involved in carbohydrate metabolic process; cell differentiation; and nervous system development. Located in perinuclear region of cytoplasm. Expressed in several structures, including P1; P2; QL; QR; and seam cell. Human ortholog(s) of this gene implicated in spermatogenic failure 9. Is an ortholog of human DPY19L2 (dpy-19 like 2).