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WormBase Tree Display for Gene: WBGene00003877

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Name Class

WBGene00003877SMapS_parentSequenceK04E7
IdentityVersion2
NameCGC_namepept-1Person_evidenceWBPerson2603
WBPerson861
Sequence_nameK04E7.2
Molecular_nameK04E7.2
K04E7.2.1
CE25039
Other_namepep-2
opt-2
CELE_K04E7.2Accession_evidenceNDBBX284606
Public_namepept-1
DB_infoDatabaseAceViewgeneXH79
WormQTLgeneWBGene00003877
WormFluxgeneWBGene00003877
NDBlocus_tagCELE_K04E7.2
PanthergeneCAEEL|WormBase=WBGene00003877|UniProtKB=Q21219
familyPTHR11654
NCBIgene180919
RefSeqproteinNM_076686.7
SwissProtUniProtAccQ21219
UniProt_GCRPUniProtAccQ21219
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:33WBPerson1971EventImportedInitial conversion from geneace
229 Apr 2009 13:55:02WBPerson9133Name_changeCGC_namepept-1
Other_nameopt-2
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classpept
Allele (85)
Possibly_affected_byWBVar02157263
StrainWBStrain00036075
WBStrain00003894
RNASeq_FPKM (74)
GO_annotation00070724
00070725
00070726
00070727
00070728
00070729
00070730
00070731
00070732
00070733
00070734
00070735
00070736
00070737
00070738
00070739
00070740
00070741
00070742
00070743
00070744
00070745
00070746
00070747
00070748
00070749
00070750
00070751
00070752
00070753
00070754
00070755
00070756
00070757
00070758
00070759
00070760
00070761
00070762
00070763
00070764
00111943
00111944
00111945
00111946
00111947
Ortholog (46)
ParalogWBGene00003876Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00003878Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
Structured_descriptionConcise_descriptionpept-1 encodes a low affinity/high capacity oligopeptide transporter; pept-1 is required for uptake of intact peptides from the intestine and thus for normal development, growth, and reproduction; genetic studies indicate that pept-1 interacts with both the daf-2/insulin- and let-363/TOR-signaling pathways to regulate lifespan and with the daf-2 pathway to influence stress response; PEPT-1 is expressed in the intestine where it localizes to the apical membrane.Paper_evidenceWBPaper00006186
WBPaper00024423
Curator_confirmedWBPerson1843
Date_last_updated05 Nov 2009 00:00:00
Automated_descriptionEnables dipeptide transmembrane transporter activity. Involved in several processes, including chemical homeostasis; nitrogen compound transport; and regulation of signal transduction. Located in apical plasma membrane. Expressed in intestine. Used to study obesity. Is an ortholog of human SLC15A1 (solute carrier family 15 member 1).Paper_evidenceWBPaper00065943
Curator_confirmed (2)
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoExperimental_modelDOID:9970Homo sapiensPaper_evidenceWBPaper00034742
Curator_confirmedWBPerson324
Date_last_updated15 Sep 2021 00:00:00
Models_disease_assertedWBDOannot00000178
Molecular_infoCorresponding_CDSK04E7.2
Corresponding_transcriptK04E7.2.1
Other_sequence (23)
Associated_featureWBsf662881
WBsf978975
WBsf1005576
WBsf1023101
WBsf235837
Experimental_infoRNAi_resultWBRNAi00090731Inferred_automaticallyRNAi_primary
WBRNAi00096440Inferred_automaticallyRNAi_primary
WBRNAi00060039Inferred_automaticallyRNAi_primary
WBRNAi00024061Inferred_automaticallyRNAi_primary
WBRNAi00108790Inferred_automaticallyRNAi_primary
WBRNAi00091099Inferred_automaticallyRNAi_primary
WBRNAi00096033Inferred_automaticallyRNAi_primary
WBRNAi00000643Inferred_automaticallyRNAi_primary
WBRNAi00063220Inferred_automaticallyRNAi_primary
WBRNAi00095881Inferred_automaticallyRNAi_primary
WBRNAi00115706Inferred_automaticallyRNAi_primary
WBRNAi00025862Inferred_automaticallyRNAi_primary
WBRNAi00023520Inferred_automaticallyRNAi_primary
WBRNAi00060036Inferred_automaticallyRNAi_primary
WBRNAi00081475Inferred_automaticallyRNAi_primary
WBRNAi00060037Inferred_automaticallyRNAi_primary
WBRNAi00105952Inferred_automaticallyRNAi_primary
WBRNAi00106043Inferred_automaticallyRNAi_primary
WBRNAi00090543Inferred_automaticallyRNAi_primary
WBRNAi00108789Inferred_automaticallyRNAi_primary
WBRNAi00090712Inferred_automaticallyRNAi_primary
WBRNAi00023263Inferred_automaticallyRNAi_primary
WBRNAi00108788Inferred_automaticallyRNAi_primary
WBRNAi00060043Inferred_automaticallyRNAi_primary
WBRNAi00095958Inferred_automaticallyRNAi_primary
WBRNAi00060038Inferred_automaticallyRNAi_primary
WBRNAi00008954Inferred_automaticallyRNAi_primary
WBRNAi00096314Inferred_automaticallyRNAi_primary
WBRNAi00096110Inferred_automaticallyRNAi_primary
WBRNAi00115709Inferred_automaticallyRNAi_primary
WBRNAi00060044Inferred_automaticallyRNAi_primary
WBRNAi00090707Inferred_automaticallyRNAi_primary
WBRNAi00096621Inferred_automaticallyRNAi_primary
WBRNAi00060040Inferred_automaticallyRNAi_primary
WBRNAi00023774Inferred_automaticallyRNAi_primary
WBRNAi00049900Inferred_automaticallyRNAi_primary
WBRNAi00115604Inferred_automaticallyRNAi_primary
WBRNAi00096187Inferred_automaticallyRNAi_primary
WBRNAi00096312Inferred_automaticallyRNAi_primary
WBRNAi00060041Inferred_automaticallyRNAi_primary
WBRNAi00096357Inferred_automaticallyRNAi_primary
WBRNAi00063354Inferred_automaticallyRNAi_primary
WBRNAi00060042Inferred_automaticallyRNAi_primary
WBRNAi00063351Inferred_automaticallyRNAi_primary
WBRNAi00096264Inferred_automaticallyRNAi_primary
WBRNAi00095672Inferred_automaticallyRNAi_primary
WBRNAi00115605Inferred_automaticallyRNAi_primary
WBRNAi00103682Inferred_automaticallyRNAi_primary
WBRNAi00096523Inferred_automaticallyRNAi_primary
Expr_patternExpr1421
Expr8048
Expr8049
Expr10732
Expr1026620
Expr1031825
Expr1153607
Expr2014823
Expr2033057
Marker28
Drives_construct (23)
Construct_productWBCnstr00004990
WBCnstr00009194
WBCnstr00013078
WBCnstr00014892
WBCnstr00016252
WBCnstr00018325
WBCnstr00037949
Regulate_expr_clusterWBPaper00045460:Co-expression_Cluster_1
WBPaper00045460:Co-expression_Cluster_2
WBPaper00045460:Co-expression_Cluster_3
WBPaper00045460:pept-1(lg601)_downregulated
WBPaper00045460:pept-1(lg601)_upregulated
AntibodyWBAntibody00002276
Microarray_results (20)
Expression_cluster (236)
Interaction (114)
Map_infoMapXPosition-2.89742Error0.002559
PositivePositive_cloneK04E7Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
Reference (57)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene