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WormBase Tree Display for RNAi: WBRNAi00108789

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Name Class

WBRNAi00108789HomolHomol_homolK04E7:RNAi
Sequence_infoPCR_productsjj_K04E7.2
ExperimentStrainWBStrain00034066
GenotypezcIs9 [hsp-60::GFP]
Delivered_byBacterial_feeding
InhibitsPredicted_geneK04E7.2Inferred_automaticallyRNAi_primary
GeneWBGene00003877Inferred_automaticallyRNAi_primary
TranscriptK04E7.2.1Inferred_automaticallyRNAi_primary
SpeciesCaenorhabditis elegans
InteractionWBInteraction000536831
ReferenceWBPaper00045460
PhenotypeWBPhenotype:0001278Remark"A marker protein for the UPR response in mitochondria is heat shock protein HSP-60. Proteome analysis revealed a decrease of HSP-60 abundance in pept-1 C. elegans. Applying pept-1(RNAi) to a C. elegans strain expressing a HSP-60::GFP fusion protein confirmed results of the proteome analysis (Figure 3B). Downregulation of pept-1 decreased the HSP-60::GFP expression by 50%."
EQ_annotationsGO_termGO:0034514PATO:0000460
Remark(Figure 3B) pept-1 RNAi
MethodRNAi