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WormBase Tree Display for Gene: WBGene00016201

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Name Class

WBGene00016201SMapS_parentSequenceC28H8
IdentityVersion2
NameCGC_nametdo-2Person_evidence (2)
Sequence_nameC28H8.11
Molecular_nameC28H8.11a
C28H8.11a.1
CE01822
C28H8.11c
CE39680
C28H8.11b
C28H8.11c.1
Other_nameCELE_C28H8.11Accession_evidenceNDBBX284603
Public_nametdo-2
DB_infoDatabase (14)
SpeciesCaenorhabditis elegans
HistoryVersion_change128 May 2004 13:30:57WBPerson1971EventImportedInitial conversion from CDS class of stlace from WS125
231 Aug 2012 11:56:39WBPerson2970Name_changeCGC_nametdo-2
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classtdo
Allele (35)
StrainWBStrain00002350
WBStrain00001238
WBStrain00001507
WBStrain00001635
WBStrain00030539
WBStrain00030538
WBStrain00030540
WBStrain00047458
RNASeq_FPKM (74)
GO_annotation (20)
Ortholog (33)
Structured_descriptionAutomated_descriptionPredicted to enable heme binding activity and tryptophan 2,3-dioxygenase activity. Predicted to be involved in tryptophan catabolic process to acetyl-CoA. Human ortholog(s) of this gene implicated in Gilles de la Tourette syndrome and familial hypertryptophanemia. Is an ortholog of human TDO2 (tryptophan 2,3-dioxygenase).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:11119Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:11708)
DOID:0111703Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:11708)
Molecular_infoCorresponding_CDSC28H8.11a
C28H8.11c
Corresponding_CDS_historyC28H8.11b:wp252
Corresponding_transcriptC28H8.11b
C28H8.11a.1
C28H8.11c.1
Other_sequence (37)
Associated_featureWBsf651085
WBsf651086
WBsf992575
WBsf992576
WBsf1014982
WBsf226737
Experimental_infoRNAi_resultWBRNAi00064449Inferred_automaticallyRNAi_primary
WBRNAi00005315Inferred_automaticallyRNAi_primary
WBRNAi00011310Inferred_automaticallyRNAi_primary
WBRNAi00027193Inferred_automaticallyRNAi_primary
WBRNAi00041426Inferred_automaticallyRNAi_primary
WBRNAi00024663Inferred_automaticallyRNAi_primary
Expr_pattern (12)
Drives_constructWBCnstr00002130
WBCnstr00002131
WBCnstr00002474
WBCnstr00004227
WBCnstr00004228
WBCnstr00028249
Construct_productWBCnstr00016476
WBCnstr00028249
AntibodyWBAntibody00002710
Microarray_results (36)
Expression_clusterWBPaper00029359_1181
WBPaper00029359_1197
WBPaper00029359_1225
WBPaper00029359_1291
WBPaper00029359_1367
WBPaper00029359_1483
WBPaper00029359_1494
WBPaper00029359_1546
WBPaper00029359_1561
WBPaper00029359_1582
WBPaper00029359_1655
WBPaper00031040:TGF-beta_adult_upregulated
WBPaper00032425:up_in_zfp-1
WBPaper00032528:L3_enriched
WBPaper00033065:clk-1(qm30)_upregulated
WBPaper00033065:cyc-1(RNAi)_upregulated
WBPaper00034761:hlh-30_downregulated
WBPaper00037946:MAB-5_interacting
WBPaper00038168:lin-15B(n744)_downregulated
WBPaper00038438:S.marcescens_24hr_upregulated_RNAseq
WBPaper00038438:S.marcescens_24hr_upregulated_TilingArray
WBPaper00042215:wdr-23(tm1817)_upregulated
WBPaper00042561:smgl-1(RNAi)_upregulated
WBPaper00044578:reduced-humidity_downregulated_microarray
WBPaper00044656:tatn-1(qd182)_upregulated
WBPaper00044736:flat_dev_expression
WBPaper00044743:wdr-23_neuron_upregulated
WBPaper00044786:emr-1(gk119)_upregulated
WBPaper00045257:bar-1(ga80)_downregulated
WBPaper00045390:tunicamycin_upregulated
WBPaper00045390:ubc-9(RNAi)_upregulated
WBPaper00045420:fertilization_upregulated_transcript
WBPaper00045521:Gender_Neutral
WBPaper00045571:germline-ablation_upregulated
WBPaper00046121:ecdoderm_unique
WBPaper00046497:B.thuringiensis_0.1mix_downregulated_6h
WBPaper00046497:B.thuringiensis_0.1mix_downregulated_12h
WBPaper00046497:B.thuringiensis_0.5mix_downregulated_6h
WBPaper00046497:B.thuringiensis_0.5mix_downregulated_12h
WBPaper00046497:B.thuringiensis_downregulated_protein
WBPaper00046691:P1_enriched
WBPaper00047131:daf-2(e1370)_upregulated_N2-background
WBPaper00047132:glp-1(ts)-25C_upregulated
WBPaper00048910:mRNA-interacting_protein
WBPaper00048923:Aging_regulated
WBPaper00048988:neuron_expressed
WBPaper00049217:TCER-1_downregulated
WBPaper00049325:CB4856_vs_N2_DEG
WBPaper00049495:starvation-refeeding_regulated
WBPaper00049545:cco-1(RNAi)_downregulated
WBPaper00049942:HeatShock_downregulated_hsf-1(RNAi)
WBPaper00049942:HeatShock_upregulated_hsf-1(+)
WBPaper00050344:AFD-neuron_enriched
WBPaper00050344:PLM-neuron_enriched
WBPaper00050488:20C_vs_25C_regulated_mir-34(gk437)_adult
WBPaper00050488:20C_vs_25C_regulated_mir-34(OverExpression)_adult
WBPaper00050488:20C_vs_25C_regulated_N2_adult
WBPaper00050488:daf-2(e1370)_vs_daf-2(e1370);mir-34(gk437)_regulated_dauer_25C
WBPaper00050726:OsmoticStress_regulated_NoFood
WBPaper00050726:starvation_regulated_LowSalt
WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day1-adult
WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
WBPaper00050859:upregulated_pgl-1(ct131)_vs_control_day1-adult
WBPaper00050990:body-muscle_expressed
WBPaper00050990:hypodermis_expressed
WBPaper00050990:intestine_expressed
WBPaper00050990:NMDA-neuron_expressed
WBPaper00050990:pharynx_expressed
WBPaper00051558:aging_regulated
WBPaper00052884:emb-4(hc60)_upregulated
WBPaper00053302:zidovudine_24h_regulated
WBPaper00053388:dauer_regulated_Cluster5
WBPaper00053599:female_vs_male_downregulated
WBPaper00053599:oocyte_vs_mitosis_upregulated
WBPaper00053615:SMO-1_target
WBPaper00053713:Starvation-induced_postdauer_vs_control_upregulated
WBPaper00054872:egl-9(sa307)_downregulated
WBPaper00055049:S.gordonii_upregulated
WBPaper00055354:eat-2(ad1116)_downregulated
WBPaper00055354:Psora-Allantoin_downregulated
WBPaper00055354:Psora_downregulated
WBPaper00055354:Rapamycin-Allantoin_downregulated
WBPaper00055354:Rapamycin-Metformin_downregulated
WBPaper00055354:Rapamycin_downregulated
WBPaper00055354:Rifampicin-Allantoin_downregulated
WBPaper00055354:Rifampicin_downregulated
WBPaper00055482:Tunicamycin_downregulated
WBPaper00055626:pry-1(mu38)_upregulated
WBPaper00055969:electromagnetic-field_downregulated
WBPaper00056039:efa-6(tm3124)_upregulated
WBPaper00056139:soil-microbiota_upregulated
WBPaper00056169:rrf-3(pk1426)_downregulated_L4
WBPaper00056169:rrf-3(pk1426)_upregulated_embryo
WBPaper00056284:ints-1(RNAi)_upregulated
WBPaper00056290:mdt-15(mg584)_upregulated
WBPaper00056443:DietaryRestriction_downregulated
WBPaper00056471:aak-1(tm1944);aak-2(ok524)_downregulated
WBPaper00056471:S.aureus-4h_downregulated_N2
WBPaper00056997:nmad-1(ok3133)_upregulated_germline_25C
WBPaper00057154:HeatShock_upregulated_mRNA
WBPaper00057254:MWCNT_downregulated_mRNA
WBPaper00058598:sin-3(tm1276)_downregulated
WBPaper00058691:sin-3(tm1276)_downregulated
WBPaper00058725:sftb-1(cer6)_upregulated
WBPaper00058725:sftb-1(cer39)_upregulated
WBPaper00058969:RIS_depleted
WBPaper00059328:mrps-5(RNAi)_downregulated_mRNA
WBPaper00059664:srbc-48(ac23)_upregulated
WBPaper00059728:5ug_cholesterol_upregulated
WBPaper00059728:20ug_cholesterol_upregulated
WBPaper00059739:hira-1(gk835598)_downregulated_L4
WBPaper00059816:crh-1(n3315)_downrgulated
WBPaper00059987:Wounding_downregulated
WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
WBPaper00060683:hlh-11(ko1)_upregulated
WBPaper00060703:nas-38(ok3407)_upregulated
WBPaper00060811:L1_vs_adult_downregulated_neural
WBPaper00061045:Y56A3A.22(cck200)_upregulated
WBPaper00061203:let-418(n3536)_upregulated
WBPaper00061203:sin-3(tm1276)_upregulated
WBPaper00061203:spr-1(ok2144)_upregulated
WBPaper00061340:hyp7_AB_lineage
WBPaper00061340:hyp7_C_lineage
WBPaper00061341:28C_24h_upregulated
WBPaper00061377:MYRF-1_interacting
WBPaper00061405:S.aureus_downregulated_starvation
WBPaper00061527:C18B2.5-haf-4_181
WBPaper00061818:ELKS-1_interacting
WBPaper00062159:hda-2(ok1479)_upregulated
WBPaper00062193:hsf-1(RNAi)_downregulated
WBPaper00062193:skn-1(RNAi)_downregulated
WBPaper00062325:muscle_depleted_coding-RNA
WBPaper00062345:bortezomib_4h_downregulated_N2
WBPaper00062345:bortezomib_4h_downregulated_zip-1(jy13)
WBPaper00062456:doxycycline_upregulated_CB4856_protein
WBPaper00062554:MAGU-2_interacting
WBPaper00062669:extracellular-vesicle_protein
WBPaper00064088:Day-1-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
WBPaper00064130:Beta-Amyloid_24h_upregulated_mRNA
WBPaper00064229:B.thuringiensis-Cry5Ba_upregulated
WBPaper00064532:pals-25(icb98)_downregulated
WBPaper00064716:paraquat_downregulated
WBPaper00064727:daf-2(e1370)_upregulated
WBPaper00065096:25C_vs_20C_downregulated
WBPaper00065096:Day10_vs_Day1_downregulated
WBPaper00065120:body-muscle-transcriptome
WBPaper00065373:Cisplatin_downregulated_WT
WBPaper00065373:sek-1(km4)_downregulated_cisplatin
WBPaper00065373:sek-1(km4)_downregulated_Ref
WBPaper00065835:Day11_vs_Day1_downregulated
WBPaper00065835:mtH2S-AP39-D0-treatment_upregulated_Day11
WBPaper00065841:2_0
WBPaper00065945:epidermis-rpoa-2(-)_downregulated_protein
WBPaper00065975:P-body_vs_WholeAnimal_depleted
WBPaper00065993:glp-1(e2141)_upregulated
WBPaper00066146:germline-inx-14(RNAi)_upregulated_PA14
cgc4386_cluster_2_5
cgc4489_group_3
WBPaper00025141:N2_Expressed_Genes
WBPaper00026929:Resveratrol_regulated_daf-16
WBPaper00026929:sir-2.1_overexpression_regulated
WBPaper00027111:eri-1(mg366)_downregulated
WBPaper00027342:alpha-Synuclein(WT)_upregulated
WBPaper00029437:dcr-1_upregulated
WBPaper00031003:24hr_muscle_depleted
WBPaper00031003:total_muscle_depleted
WBPaper00031532:Larva_Pan_Neuronal_Depleted
WBPaper00032062:age_regulated_genes
WBPaper00034757:up_by_oxidative_stress
WBPaper00035588:alg-1(-)_upregulated
WBPaper00035873:dpy-9_regulated
WBPaper00035873:dpy-10_regulated
WBPaper00035873:osm-8_regulated
WBPaper00036123:Cadmium_regulated
WBPaper00036130:mir-243_up_regulated
WBPaper00038172:crh-1null_down_regulated
WBPaper00039866:ClassComp_daf-19_downregulated
WBPaper00040184:hcf-1nc_sir-2.1nc_daf-2up
WBPaper00040210:Chlorpyrifos_Diazinon_24C_regulated
WBPaper00040603:tdp-1(lf)_down_vs_N2_FC_1.2
WBPaper00040876:mir-35_downregulated
WBPaper00041002:HF_3d_0.2mM_Up
WBPaper00041002:HF_3d_2.0mM_Up
WBPaper00041606:CE_X.nematophila_regulated
WBPaper00041906:I-3690_vs_OP50_3d
WBPaper00041939:control_vs_EtBr-exposed_48h
WBPaper00041939:control_vs_EtBr-exposed_51h
WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
WBPaper00041939:EtBr-exposed_vs_UVC-exposed_48h
WBPaper00041939:EtBr-exposed_vs_UVC-exposed_51h
WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_48h
WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_51h
WBPaper00042258:DA1877_upregulated_GravidAdult
WBPaper00042274:tbx-2(bx59)_upregulated
WBPaper00045263:isp-1(qm150)_upregulated
WBPaper00045263:nuo-6(qm200)_upregulated
WBPaper00045673:colistin_upregulated
WBPaper00053550:daf-19(m86)_downregulated_3-fold-embryo
WBPaper00055899:nitroguanidine_regulated
WBPaper00057098:SiO2-nanoparticles_downregulated
[cgc6390]:Cluster_C
Interaction (40)
Map_infoMapIIIPosition-1.43491
PositivePositive_cloneC28H8Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00038491
WBPaper00049828
WBPaper00050548
WBPaper00055090
WBPaper00064186
WBPaper00064989
WBPaper00066248
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene