WormBase Tree Display for Gene: WBGene00012980

WBGene00012980 SMap: S_parent: Sequence: Y48B6A
  Identity: Version: 2
    Name: CGC_name: efhd-1 Paper_evidence: WBPaper00041587
      Sequence_name: Y48B6A.6
      Molecular_name: Y48B6A.6a
        Y48B6A.6a.1
        CE32970
        Y48B6A.6b
        CE41852
        Y48B6A.6c
        CE41853
        Y48B6A.6a.2
        Y48B6A.6b.1
        Y48B6A.6c.1
      Other_name: EFhd2 orthologue Paper_evidence: WBPaper00038072
        CELE_Y48B6A.6 Accession_evidence: NDB BX284602
      Public_name: efhd-1
    DB_info: Database: AceView gene 2O479
        WormQTL gene WBGene00012980
        WormFlux gene WBGene00012980
        NDB locus_tag CELE_Y48B6A.6
        Panther gene CAEEL|WormBase=WBGene00012980|UniProtKB=Q9U2A6
          family PTHR13025
        NCBI gene 175073
        RefSeq protein NM_064560.7
            NM_182166.7
            NM_001129185.5
        TREEFAM TREEFAM_ID TF320736
        TrEMBL UniProtAcc Q8I0Z7
            A8XMZ5
            Q9U2A6
        UniProt_GCRP UniProtAcc Q9U2A6
    Species: Caenorhabditis elegans
    History: Version_change (2)
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: efhd
    Allele (338)
    Strain: WBStrain00001460
    RNASeq_FPKM (74)
    GO_annotation: 00005433
      00119935
    Ortholog (37)
    Structured_description: Concise_description: efhd-1 encodes the C. elegans ortholog of the mammalian EF hand domain-containing proteins EFHD1 and EFHD2; large-scale expression studies report that efhd-1 is expressed in the pharynx, the body wall muscle, and the nervous system. Paper_evidence: WBPaper00031006
            WBPaper00038072
            WBPaper00041587
          Curator_confirmed: WBPerson1843
          Date_last_updated: 24 Nov 2014 00:00:00
      Automated_description: Predicted to enable calcium ion binding activity. Is an ortholog of human EFHD1 (EF-hand domain family member D1). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: Y48B6A.6a
      Y48B6A.6b
      Y48B6A.6c
    Corresponding_CDS_history: Y48B6A.6:wp92
      Y48B6A.6b:wp184
    Corresponding_transcript: Y48B6A.6a.1
      Y48B6A.6a.2
      Y48B6A.6b.1
      Y48B6A.6c.1
    Other_sequence (40)
    Associated_feature (8)
  Experimental_info: RNAi_result: WBRNAi00056884 Inferred_automatically: RNAi_primary
      WBRNAi00037235 Inferred_automatically: RNAi_primary
      WBRNAi00020738 Inferred_automatically: RNAi_primary
    Expr_pattern: Chronogram1627
      Expr7002
      Expr1017855
      Expr1035758
      Expr1160336
      Expr2011187
      Expr2029423
    Drives_construct: WBCnstr00002338
    Microarray_results (30)
    Expression_cluster: WBPaper00029359_1183
      WBPaper00029359_1280
      WBPaper00029359_1310
      WBPaper00029359_1362
      WBPaper00029359_1364
      WBPaper00029359_1444
      WBPaper00029359_1504
      WBPaper00029359_1578
      WBPaper00029359_1604
      WBPaper00029359_1636
      WBPaper00032425:down_in_zfp-1
      WBPaper00033065:cyc-1(RNAi)_upregulated
      WBPaper00035269:cde-1_regulated
      WBPaper00036375:enriched_in_PVD_OLL
      WBPaper00037946:EGL-5_interacting
      WBPaper00037950:A-class-motor-neurons_L2-larva_expressed
      WBPaper00037950:bodywall-muscle_L2-larva_expressed
      WBPaper00037950:bodywall-muscle_larva_enriched
      WBPaper00037950:bodywall-muscle_larva_SelectivelyEnriched
      WBPaper00037950:coelomocytes_L2-larva_expressed
      WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
      WBPaper00037950:excretory-cell_L2-larva_expressed
      WBPaper00037950:GABAergic-motor-neurons_L2-larva_expressed
      WBPaper00037950:glr-1(+)-neurons_L2-larva_expressed
      WBPaper00037950:hypodermis_L1-larva_expressed
      WBPaper00037950:hypodermis_L3-L4-larva_expressed
      WBPaper00038168:lin-15B(n744)_upregulated
      WBPaper00038438:S.marcescens_24hr_downregulated_TilingArray
      WBPaper00042215:wdr-23(tm1817)_upregulated
      WBPaper00044260:nicotic-acid_downregulated
      WBPaper00044316:CH3HgCl_7.5uM_upregulated
      WBPaper00044736:oscillating_dev_expression
      WBPaper00044786:emr-1(gk119)_upregulated
      WBPaper00044786:emr-1(RNAi);lem-2(tm1582)_upregulated
      WBPaper00045314:S.aureus-induced_hlh-30(tm1978)
      WBPaper00045314:S.aureus-induced_N2
      WBPaper00045316:prg-1_upregulated_L2
      WBPaper00045521:Gender_Neutral
      WBPaper00046497:B.thuringiensis_0.1mix_upregulated_6h
      WBPaper00046497:B.thuringiensis_0.1mix_upregulated_12h
      WBPaper00046497:B.thuringiensis_0.5mix_upregulated_6h
      WBPaper00046497:B.thuringiensis_0.5mix_upregulated_12h
      WBPaper00046805:csr-1(RNAi)_upregulated_Set1
      WBPaper00047131:daf-2(e1370)_upregulated_N2-background
      WBPaper00048690:hermaphrodite-Z1-Z4-daughter_enriched
      WBPaper00048690:male-Z1-Z4-daughter_enriched
      WBPaper00048690:male-Z1-Z4_enriched
      WBPaper00048923:Aging_regulated
      WBPaper00048988:neuron_enriched
      WBPaper00048988:neuron_expressed
      WBPaper00049545:jmjd-3.1(+)_downregulated
      WBPaper00049732:blmp-1(tm548)_vs_N2_upregulated
      WBPaper00049905:Age_variant_expression
      WBPaper00050053:muscle_enriched_Day4
      WBPaper00050053:muscle_enriched_Day12
      WBPaper00050094:mes-2(bn11)_upregulated
      WBPaper00050094:mes-6(bn66)_upregulated
      WBPaper00050448:KGB-1-induced
      WBPaper00050488:20C_vs_25C_regulated_N2_adult
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C
      WBPaper00050514:CEBP-1_interacting
      WBPaper00050801:DAF-16_dauer_regulome
      WBPaper00050859:upregulated_glh-1(gk100)_vs_control_day1-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day1-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00050859:upregulated_pgl-1(ct131)_vs_control_day1-adult
      WBPaper00050990:GABAergic-neuron_expressed
      WBPaper00050990:hypodermis_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00050990:NMDA-neuron_expressed
      WBPaper00050990:pharynx_expressed
      WBPaper00050990:seam_expressed
      WBPaper00051021:4-bromodiphenyl-ether_upregulated
      WBPaper00051039:germline_enriched
      WBPaper00051245:body-wall-muscle_cytoplasm_expressed
      WBPaper00051245:body-wall-muscle_nucleus_expressed
      WBPaper00051352:Long-Term-Association-Memory_upregulated
      WBPaper00051558:aging_regulated
      WBPaper00052884:emb-4(hc60)_upregulated
      WBPaper00053184:sma-2(rax5)_upregulated
      WBPaper00053184:sma-4(rax3)_upregulated
      WBPaper00053295:lin-22(ot269)_upregulated
      WBPaper00053308:SMG-2_associated_NMD(-)_unaltered_ClassII
      WBPaper00053321:PGCs_depleted_NuGen
      WBPaper00053388:dauer_regulated_Cluster5
      WBPaper00053599:mitosis_vs_meiosis_downregulated
      WBPaper00053599:oocyte_vs_mitosis_downregulated
      WBPaper00053606:elt-2(ca15)_vs_elt-2(ca15);elt-7(tm840)_upregulated
      WBPaper00053606:N2_vs_elt-2(ca15);elt-7(tm840)_upregulated
      WBPaper00053814:15C_downregulated_OP50
      WBPaper00054758:alg-1(gk204)_upregulated
      WBPaper00055049:S.gordonii_upregulated
      WBPaper00055354:eat-2(ad1116)_downregulated
      WBPaper00055354:Psora-Allantoin_upregulated
      WBPaper00055354:Rapamycin-Metformin_upregulated
      WBPaper00055354:Rapamycin-Rifampicin_upregulated
      WBPaper00055354:Rapamycin_downregulated
      WBPaper00055354:Rifampicin-Allantoin_upregulated
      WBPaper00055354:Rifampicin_upregulated
      WBPaper00055482:pmt-2(RNAi)_upregulated
      WBPaper00055971:nhl-2(ok818)_20C_upregulated
      WBPaper00056090:E.faecalis_upregulated_hpx-2(dg047)
      WBPaper00056139:soil-microbiota_upregulated
      WBPaper00056218:daf-16(mu86)_upregulated_Day7
      WBPaper00056275:P.aeruginosa_downregulated
      WBPaper00056275:P.aeruginosa_downregulated_atf-7(qd22qd130)_dependent
      WBPaper00056275:P.aeruginosa_downregulated_pmk-1(km25)_dependent
      WBPaper00056284:ints-4(RNAi)_upregulated
      WBPaper00056326:zip-3(gk3164)_upregulated_P.aeruginosa-infected
      WBPaper00056443:DietaryRestriction_upregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_downregulated
      WBPaper00056471:S.aureus-4h_downregulated_N2
      WBPaper00056826:SGP_biased
      WBPaper00056855:his-72(uge40)_upregulated
      WBPaper00056997:nmad-1(ok3133)_upregulated_germline_25C
      WBPaper00057154:HeatShock_downregulated_miRNA-target
      WBPaper00057154:HeatShock_upregulated_mRNA
      WBPaper00057158:mdt-15(tm2182)_dependent_15C_downregulated
      WBPaper00057288:Cold_upregulated_transcript
      WBPaper00057288:iff-1(RNAi)_upregulated_transcript
      WBPaper00058598:sin-3(tm1276)_downregulated
      WBPaper00058691:cfp-1(tm6369)_downregulated
      WBPaper00058725:sftb-1(cer6)_upregulated
      WBPaper00059224:tph-1(mg280)_upregulated
      WBPaper00059328:mrps-5(RNAi)_downregulated_mRNA
      WBPaper00059471:EGL-43_interacting
      WBPaper00059895:wounding_upregulated
      WBPaper00059987:Wounding_upregulated
      WBPaper00060100:SiNP_upregulated_mRNA
      WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
      WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
      WBPaper00060661:sensory-neuron_enriched
      WBPaper00060683:hlh-11(ko1)_upregulated
      WBPaper00060703:nas-38(ok3407)_upregulated
      WBPaper00060811:L1_vs_adult_downregulated_neural
      WBPaper00061203:let-418(n3536)_upregulated
      WBPaper00061203:sin-3(tm1276)_upregulated
      WBPaper00061203:spr-1(ok2144)_upregulated
      WBPaper00061340:ABarpaaa_lineage
      WBPaper00061340:AMso_parent
      WBPaper00061340:Body_wall_muscle
      WBPaper00061340:I1_parent
      WBPaper00061340:Neuroblast_ASH_RIB
      WBPaper00061340:Neuroblast_AWC_SAAVx
      WBPaper00061340:Neuroblast_BAG_SMDVx
      WBPaper00061340:Neuroblast_I6_M5
      WBPaper00061340:Parent_of_AMsh_URB
      WBPaper00061340:Parent_of_hyp3_ILsoDx
      WBPaper00061341:28C_24h_upregulated
      WBPaper00061341:28C_48h_upregulated
      WBPaper00061479:ubc-9(ne4833)_upregulated
      WBPaper00061527:ldb-1_2877-scd-1_3086
      WBPaper00061527:T12G3.1_17-T12G3.1_18846
      WBPaper00061651:Gonadal_sheath_cell_enriched
      WBPaper00061818:ELKS-1_interacting
      WBPaper00061902:camt-1(ok515)_regulated_URX-AQR-PQR
      WBPaper00062056:lin-35(n745)_upregulated
      WBPaper00062156:jmjd-5(zr1234)_downregulated_germline
      WBPaper00062159:hda-2(ok1479)_upregulated
      WBPaper00062325:muscle_enriched_coding-RNA
      WBPaper00062345:bortezomib_4h_upregulated_N2
      WBPaper00064130:Beta-Amyloid_24h_downregulated_mRNA
      WBPaper00064306:Agaro-oligosaccharides_upregulated
      WBPaper00064315:mes-4(bn73)_upregulated_EGCs
      WBPaper00064315:mrg-1(qa6200)_upregulated_PGCs
      WBPaper00064735:bet-1(RNAi)_vs_N2_upregulated
      WBPaper00064762:freezing-thaw_regulated
      WBPaper00064871:hypoxia_downregulated_F1
      WBPaper00064992:heat-shock_upregulated
      WBPaper00065086:JU1400_N.ausubeli_regulated
      WBPaper00065086:JU1400_N.ferruginous_regulated
      WBPaper00065086:N2_N.ausubeli_regulated
      WBPaper00065086:N2_N.ferruginous_regulated
      WBPaper00065096:Day10_vs_Day1_upregulated
      WBPaper00065373:sek-1(km4)_upregulated_cisplatin
      WBPaper00065835:Day11_vs_Day1_upregulated
      WBPaper00065835:mtH2S-AP39-D0-treatment_downregulated_Day11
      WBPaper00065841:13_0
      WBPaper00065841:18_0
      WBPaper00065841:21_0
      WBPaper00066085:sin-3(syb2172)_upregulated
      WBPaper00066110:tetraploid_vs_diploid_upregulated
      cgc4386_cluster_6_1
      cgc4489_group_16
      WBPaper00025032:cluster_2
      WBPaper00025032:cluster_10
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00025141:unc-4::GFP_Expressed_Genes
      WBPaper00026929:Resveratrol_regulated_daf-16
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00029437:dcr-1_upregulated
      WBPaper00031252:AIN-1_IP_enriched
      WBPaper00035227:heat_shock_regulated
      WBPaper00036123:Cadmium_regulated
      WBPaper00036130:mir-243_up_regulated
      WBPaper00037695:WC_5-day
      WBPaper00040210:Chlorpyrifos_Diazinon_24C_regulated
      WBPaper00040858:eQTL_regulated_developing
      WBPaper00040858:eQTL_regulated_juvenile
      WBPaper00040985:AIN-2_asynchronous_muscle
      WBPaper00041002:HF_11d_2.0mM_Down
      WBPaper00041609:hpl-1_hpl-2_upregulated
      WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
      WBPaper00041939:UVC-EtBr-exposed_vs_EtBr-exposed_51h
      WBPaper00041960:N2_fasting_upregulated_9hto12h
      WBPaper00041960:N2_fasting_upregulated_anytime
      WBPaper00042128:gei-8(ok1671)_upregulated
      WBPaper00042234:xpa-1_upregulated
      WBPaper00048989:eat-2(ad465)_rapamycin_downregulated
      [cgc5767]:cluster_2
      [cgc5767]:expression_class_E
      [cgc5767]:expression_class_E_pi(53_min)
      [cgc5767]:expression_class_E_pi(66_min)
      [cgc5767]:expression_class_M
      [cgc5767]:expression_class_ME
    Interaction (11)
  Map_info: Map: II Position: 22.5653
    Positive: Positive_clone: Y48B6A Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00038072
    WBPaper00038491
    WBPaper00041587
    WBPaper00055090
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene